Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Susan Brenner-Morton"'
Proprioception plays a crucial role in laryngeal function. Further, dysfunctional proprioception likely contributes to disorders such as laryngeal dystonia, dysphagia and vocal fold paresis. Despite this, the physiology of laryngeal proprioception is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f42cbb18a18e86a13a850c3b98bd4675
https://doi.org/10.1101/2023.03.02.530889
https://doi.org/10.1101/2023.03.02.530889
SummaryThe formation of spinal sensory-motor circuits requires the diversification of proprioceptive sensory neurons (pSNs). During embryonic development, pSNs acquire molecular identities aligned with the limb muscle that they supply, but the extent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b8d7987289674f5dd73fffea3ecb0cc
https://doi.org/10.1101/2022.08.18.504408
https://doi.org/10.1101/2022.08.18.504408
Autor:
Thomas M. Jessell, Lora B. Sweeney, Jerry H. Yang, Linjing Fang, Jay B. Bikoff, Alina Salamatina, Chris Kintner, Susan Brenner-Morton
Publikováno v:
Neuroscience. 450
Amyotrophic lateral sclerosis (ALS) leads to a loss of specific motor neuron populations in the spinal cord and cortex. Emerging evidence suggests that interneurons may also be affected, but a detailed characterization of interneuron loss and its pot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79f8fc04f95a125f123dece9342fa648
https://pubmed.ncbi.nlm.nih.gov/32858144
https://pubmed.ncbi.nlm.nih.gov/32858144
Autor:
Thomas M. Jessell, Susan Brenner-Morton, Warren G. Tourtellotte, Andrew J. Murray, William Paganini Mayer, Turgay Akay
Publikováno v:
Journal of neurophysiology. 120(5)
Terrestrial animals increase their walking speed by increasing the activity of the extensor muscles. However, the mechanism underlying how this speed-dependent amplitude modulation is achieved remains obscure. Previous studies have shown that group I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::672c7711cac82e09bfd78f0a94e157ba
https://pubmed.ncbi.nlm.nih.gov/30133381
https://pubmed.ncbi.nlm.nih.gov/30133381
Autor:
Jerry H. Yang, Jeremy S. Dasen, Susan Brenner-Morton, Jay B. Bikoff, Mariano I. Gabitto, Thomas M. Jessell, Myungin Baek, Chris Kintner, Lora B. Sweeney, Esteban G. Tabak
Publikováno v:
Neuron. 97:341-355.e3
Summary Motor output varies along the rostro-caudal axis of the tetrapod spinal cord. At limb levels, ∼60 motor pools control the alternation of flexor and extensor muscles about each joint, whereas at thoracic levels as few as 10 motor pools suppl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1a7be0173f8429773b521c3e1b3535b
https://doi.org/10.1016/j.neuron.2017.12.029
https://doi.org/10.1016/j.neuron.2017.12.029
Autor:
Susan Brenner-Morton, Wayne A. Hendrickson, Risa Siegel, Richard Axel, Filippo Mancia, Zahra Assur, Monica Mendelsohn, Yonghua Sun, Ira Schieren
Publikováno v:
Proceedings of the National Academy of Sciences. 104:4303-4308
mAbs that are sensitive to protein conformation can be helpful in studies of protein structure and function; in particular, mAb fragments are useful reagents in membrane protein crystallization. We immunized mice with the rat 5HT2c serotonin receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01de1983a95e51c72eb319f1e16b1ea8
https://doi.org/10.1073/pnas.0700301104
https://doi.org/10.1073/pnas.0700301104
Autor:
Jay B. Bikoff, Carolyn Diaz, George Z. Mentis, Andrew Miri, Thomas M. Jessell, Susan Brenner-Morton, Andre F. Rivard, Francisco J. Alvarez, Erica Famojure, Estelle Drobac, Timothy A. Machado, Mariano I. Gabitto
Publikováno v:
Cell. 165(1)
Animals generate movement by engaging spinal circuits that direct precise sequences of muscle contraction, but the identity and organizational logic of local interneurons that lie at the core of these circuits remain unresolved. Here, we show that V1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7fa02d5843676535c1a3ae98daae86b
https://pubmed.ncbi.nlm.nih.gov/26949184
https://pubmed.ncbi.nlm.nih.gov/26949184
Publikováno v:
Cell. 123:477-491
Spinal motor neurons acquire specialized "pool" identities that determine their ability to form selective connections with target muscles in the limb, but the molecular basis of this striking example of neuronal specificity has remained unclear. We s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13a19d824104b381d9ab89729b4b671a
https://doi.org/10.1016/j.cell.2005.09.009
https://doi.org/10.1016/j.cell.2005.09.009
Autor:
P. Rashbass, Johan Ericson, Andreas Schedl, Thomas M. Jessell, Atsushi Kawakami, Veronica van Heyningen, James Briscoe, Susan Brenner-Morton
Publikováno v:
Cell. 90(1):169-180
Distinct classes of motor neurons and ventral interneurons are generated by the graded signaling activity of Sonic hedgehog (Shh). Shh controls neuronal fate by establishing different progenitor cell populations in the ventral neural tube that are de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::529b5481defb99df91de1299b058f11d
Autor:
Derya Unutmaz, Zuoming Sun, Mary Jean Sunshine, Susan Brenner-Morton, Dan R. Littman, Yong-Rui Zou, Alessandra Pierani, Reina E. Mebius
Publikováno v:
Science (New York, N.Y.). 288(5475)
Most developing thymocytes undergo apoptosis because they cannot interact productively with molecules encoded by the major histocompatibility complex. Here, we show that mice lacking the orphan nuclear hormone receptor RORγ lose thymic expression of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11106cc01987992235c88f4dfff82860
https://pubmed.ncbi.nlm.nih.gov/10875923
https://pubmed.ncbi.nlm.nih.gov/10875923