Zobrazeno 1 - 10
of 252
pro vyhledávání: '"Susan Band, Horwitz"'
PDF - 489K, Table S1. Antibodies for Western Blot Analyses. Table S2. Identification of proteins differentially expressed in drug-sensitive and -resistant cells. Fig. S1. Expression levels of stathmin, Ser16-P-stathmin (A) and galectin-1 (B) in drug-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acd5845d8a1755eca061640d6986822b
https://doi.org/10.1158/1535-7163.22503946.v1
https://doi.org/10.1158/1535-7163.22503946.v1
Publikováno v:
J Nat Prod
Photoaffinity labeling approaches have historically been used in pharmacology to identify molecular targets. This methodology has played a pivotal role in identifying drug-binding domains and searching for novel compounds that may interact at these d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::194d02c6dd02db6b2018a97e40486ece
https://doi.org/10.1021/acs.jnatprod.2c00106
https://doi.org/10.1021/acs.jnatprod.2c00106
Autor:
Susan Band Horwitz, Harriet O. Smith, Gary L. Goldberg, Eric R. Prossnitz, Clifford R. Qualls, Hugo Arias-Pulido, Juan Lin, Tiffany M. Hebert, Christine H. Kim, Marissa J. Ramirez, Jurriaan Brouwer-Visser, Gloria S. Huang
Purpose: This study was undertaken to examine the role of the insulin-like growth factor (IGF) signaling pathway in the response of ovarian cancer cells to Taxol and to evaluate the significance of this pathway in human epithelial ovarian tumors.Expe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ed4976505daec1f5287aa55d839e8ce
https://doi.org/10.1158/1078-0432.c.6518928.v1
https://doi.org/10.1158/1078-0432.c.6518928.v1
Autor:
Hayley M. McDaid, Susan Band Horwitz, Gary L. Goldberg, Amos B. Smith, B. Scott Freeze, Lluis Lopez-Barcons, Gloria S. Huang
Purpose: To evaluate the drug combination of discodermolide and Taxol in human ovarian cancer cells and in an in vivo model of ovarian carcinoma.Experimental Design: The combination index method was used to evaluate the interaction of Taxol and disco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3efcd5e6b60c555407d0c28993a16f4
https://doi.org/10.1158/1078-0432.c.6518529.v1
https://doi.org/10.1158/1078-0432.c.6518529.v1
Autor:
Hayley M. McDaid, Susan Band Horwitz, Gary L. Goldberg, Amos B. Smith, B. Scott Freeze, Lluis Lopez-Barcons, Gloria S. Huang
Supplementary Figure S1 from Potentiation of Taxol Efficacy by Discodermolide in Ovarian Carcinoma Xenograft-Bearing Mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a941d62e8eb71c65b5689aab20f12301
https://doi.org/10.1158/1078-0432.22441470.v1
https://doi.org/10.1158/1078-0432.22441470.v1
Autor:
Susan Band Horwitz, Harriet O. Smith, Gary L. Goldberg, Eric R. Prossnitz, Clifford R. Qualls, Hugo Arias-Pulido, Juan Lin, Tiffany M. Hebert, Christine H. Kim, Marissa J. Ramirez, Jurriaan Brouwer-Visser, Gloria S. Huang
Supplementary Data from Insulin-like Growth Factor 2 Expression Modulates Taxol Resistance and Is a Candidate Biomarker for Reduced Disease-Free Survival in Ovarian Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4af34962147213cdc6c0757ea3de5344
https://doi.org/10.1158/1078-0432.22442106
https://doi.org/10.1158/1078-0432.22442106
Autor:
Mary Ann Jordan, Claudette Briand, Leslie Wilson, Susan Band Horwitz, Diane Braguer, Kathy Kamath, Stéphane Honore
Discodermolide is a new microtubule-targeted antimitotic drug in Phase I clinical trials that, like paclitaxel, stabilizes microtubule dynamics and enhances microtubule polymer mass in vitro and in cells. Despite their apparently similar binding site
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5569750f8752827272f2a95929fab62f
https://doi.org/10.1158/0008-5472.c.6493860.v1
https://doi.org/10.1158/0008-5472.c.6493860.v1
Autor:
Susan Band Horwitz, Román Pérez-Soler, Steven Keller, Marie Lia, Aaron Grossman, Lluis Lopez-Barcons, Hayley M. McDaid
Supplementary Figures S1 & S2 from Enhancement of the Therapeutic Efficacy of Taxol by the Mitogen-Activated Protein Kinase Kinase Inhibitor CI-1040 in Nude Mice Bearing Human Heterotransplants
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7532a560f8dcc7e137950342abf4139f
https://doi.org/10.1158/0008-5472.22364421
https://doi.org/10.1158/0008-5472.22364421
Autor:
Hayley M. McDaid, Susan Band Horwitz, Roman Pérez-Soler, Steven M. Keller, Lluis Lopez-Barcons, Han-Guang Yan, Chia-Ping Huang Yang, Marie-Emmanuelle Legrier
Supplementary Figure 2 from Targeting Protein Translation in Human Non–Small Cell Lung Cancer via Combined MEK and Mammalian Target of Rapamycin Suppression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d3a3928cb8aeefabd4d41decee65650
https://doi.org/10.1158/0008-5472.22370444
https://doi.org/10.1158/0008-5472.22370444
Autor:
Susan Band Horwitz, Román Pérez-Soler, Steven Keller, Marie Lia, Aaron Grossman, Lluis Lopez-Barcons, Hayley M. McDaid
Taxol may contribute to intrinsic chemoresistance by activating the mitogen-activated protein kinase kinase (MEK)/extracellular signal-regulated kinase (ERK) cytoprotective pathway in human cancer cell lines and tumors. We have previously shown addit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f971ca16f15024b2bfc540245648840
https://doi.org/10.1158/0008-5472.c.6494184.v1
https://doi.org/10.1158/0008-5472.c.6494184.v1