Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Susan Ball-Kell"'
Autor:
Darren J. Wozniak, Andre Kajdacsy-Balla, Virgilia Macias, Susan Ball-Kell, Morgan L. Zenner, Wenjun Bie, Angela L. Tyner
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
PTEN is often lost in prostate cancer. In this study, the authors show that PTEN can act as a protein phosphatase that targets active PTK6, thereby regulating its oncogenic signaling in prostate cancer progression.
Externí odkaz:
https://doaj.org/article/18dc9ef9edce4840868fb91007225a76
Publikováno v:
Nutrition and Dietary Supplements, Vol 2011, Iss default, Pp 19-30 (2011)
Levent Dirikolu1, Thushara Chakkath1, Susan Ball-Kell2, Christy Elamma2, David J Schaeffer11Department of Comparative Biosciences, 2Veterinary Diagnostic Laboratory, College of Veterinary Medicine, University of Illinois at Urbana-Champaign, Urbana,
Externí odkaz:
https://doaj.org/article/a60b74cbf07d4fcba0c52440c80d902a
Publikováno v:
The Journal of investigative dermatology
Protein tyrosine kinase 6 (PTK6, also called BRK) is an intracellular tyrosine kinase expressed in the epithelial linings of the gastrointestinal tract and the skin, where it is expressed in nondividing differentiated cells. We found that PTK6 expres
Autor:
Morgan L. Zenner, Virgilia Macias, Andre Kajdacsy-Balla, Angela L. Tyner, Wenjun Bie, Darren J. Wozniak, Susan Ball-Kell
Publikováno v:
Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
PTEN activity is often lost in prostate cancer. We show that the tyrosine kinase PTK6 (BRK) is a PTEN substrate. Phosphorylation of PTK6 tyrosine 342 (PY342) promotes activation, while phosphorylation of tyrosine 447 (PY447) regulates auto-inhibition
Autor:
Susan Ball-Kell, Yu Zheng, Andrea Haegebarth, Angela L. Tyner, Wenjun Bie, Jessica Gierut, Robert J. Carroll
Background & Aims Protein tyrosine kinase 6 (PTK6) is expressed throughout the gastrointestinal tract and is a negative regulator of proliferation that promotes differentiation and DNA-damage−induced apoptosis in the small intestine. PTK6 is not ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e873ae533ce698711cb695b1359fef68
https://europepmc.org/articles/PMC3448944/
https://europepmc.org/articles/PMC3448944/
Publikováno v:
Journal of the American Association for Laboratory Animal Science : JAALAS. 48(4)
Mite infestation of mice remains a persistent problem for many institutions, leading to numerous health problems and creating unknown and unwanted variables for research. In this study, mice with mite infestation demonstrated significantly higher lev
Autor:
James, Artwohl, Susan, Ball-Kell, Tibor, Valyi-Nagy, Steven P, Wilson, Ying, Lu, Thomas J, Park
Publikováno v:
Comparative medicine. 59(1)
Herpes simplex virus type 1 (HSV1) is widely used as a gene delivery vector in a variety of laboratory animals. In a recent study, a thymidine-kinase–inactive (replication-conditional) HSV1 used as a delivery vector was lethal in naked mole rats, w
Publikováno v:
Lab Animal. 38:258-259
Publikováno v:
Neurosurgery. 49:545-546
Autor:
Susan Ball-Kell, David J. Schaeffer, Thushara Chakkath, Christy Elamma, Levent Dirikolu, Timothy M. Fan
Publikováno v:
Nutrition and Dietary Supplements. :125
Levent Dirikolu1, Thushara Chakkath1, Susan Ball-Kell2, Christy Elamma2, Timothy M Fan3, David J Schaeffer11Department of Comparative Biosciences, 2Veterinary Diagnostic Laboratory, 3Comparative Oncology Research Laboratory, Department of Veterinary