Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Susan B. Nunez"'
Publikováno v:
Pediatric Cardiology. 30:818-823
Internationally, there have been isolated case reports published of children presenting with dilated cardiomyopathy (DCM) in the setting of undiagnosed rickets. Although there has been an increased prevalence of rickets in the United States, there ha
Publikováno v:
Pediatric Blood & Cancer. 46:258-261
Chemotherapy-related growth failure is a significant problem in children with acute lymphoblastic leukemia (ALL) and other childhood cancers. Growth impairment after cranial radiation (CR) can result in diminished adult height, but growth failure fol
Autor:
Susan B. Nunez, Sheue yann Cheng, Gonzalo Barrera-Hernandez, Paul H. Driggers, James H. Segars, Chia Lin Yu
Publikováno v:
Biochemical and Biophysical Research Communications. 239:617-620
The estrogen receptor (ER) is a ligand-dependent transcription factor which regulates growth, development, differentiation and reproduction. To test the hypothesis that the diverse effects of the ER could be mediated by interacting with other transcr
Autor:
Pam Thomas, James D. Malley, Jerry R. Reel, Kevin M. Barnes, Richard P. Blye, Susan B. Nunez, Gordon B. Cutler
Publikováno v:
Reproductive Toxicology. 10:373-377
The aromatase inhibitor, fadrozole hydrochloride (CGS 16949A), was developed for the treatment of breast cancer, and has not been available for pediatric use because of the lack of information about potential reproductive toxicology. To determine the
Publikováno v:
Current oncology reports. 9(6)
Because of therapeutic advances over the past 50 years, long-term survival is now a reality for nearly 80% of children and adolescents diagnosed with cancer. The growing population of childhood cancer survivors is notable for its vulnerability to adv
Publikováno v:
The Journal of clinical endocrinology and metabolism. 88(12)
We administered the aromatase inhibitor fadrozole to 16 girls with gonadotropin-independent precocious puberty due to the McCune-Albright syndrome. The girls’ ages ranged from 3.2–9.7 yr, and their bone ages ranged from 5.75–14.25 yr. After bas
Autor:
Gina M. Many, Jung-Jun Park, Christopher F. Spurney, Gabriel I. Uwaifo, Natasa Janicic, James M. Hagberg, Maria-Eugenia Hurtado, Natella Rakhmanina, William E. Kraus, Joseph A. Houmard, Susan B. Nunez, Eric P. Hoffman, Jesse M. Damsker, Lauren Q. Rhee, Charles J. Tanner
Publikováno v:
Medicine & Science in Sports & Exercise. 43:683-684
Autor:
Susan B. Nunez, Olivier Braissant, Jeffrey A. Medin, Walter Wahli, Lawrence Kemp, Keiko Ozato, James H. Segars
Publikováno v:
Molecular and cellular endocrinology. 127(1)
Estrogen receptors regulate transcription of genes essential for sexual development and reproductive function. Since the retinoid X receptor (RXR) is able to modulate estrogen responsive genes and both 9-cis RA and fatty acids influenced development
Publikováno v:
The Journal of clinical endocrinology and metabolism. 81(5)
To evaluate the relative usefulness of insulin-like growth factor I (IGF-I) and IGF-binding protein-3 (IGFBP-3) in screening for GH status, GH stimulation (arginine-insulin/L-DOPA) tests and overnight GH studies (every 20 min sampling) were performed
Publikováno v:
Environmental Health Perspectives
Di(2-ethylhexyl) phthalate (DEHP) is used to make polyvinyl chloride (PVC) plastic tubing soft and flexible. Animal data show that adverse effects of DEHP exposure may include reduced fertility, reduced sperm production in males, and ovarian dysfunct