Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Susan B. Masters"'
Autor:
Selma Omer, Susan B. Masters, Haile T. Debas, Helen Loeser, Patricia S. O'Sullivan, Gilles R.X. Hickson, Charles A. Mkony, Raymond D. Blind, Stephanie Taché, Kevin H. Souza
Publikováno v:
Biochem Mol Biol Educ
Teaching to large classes is often challenging particularly when the faculty and teaching resources are limited. Innovative, less staff intensive ways need to be explored to enhance teaching and to engage students. We describe our experience teaching
Publikováno v:
Advances in Enzyme Regulation. 30:75-87
Structural, biochemical and molecular genetic studies of EF-Tu, p21ras and alpha s have begun to reveal the inner workings of the molecular machine used by these and other GTP-binding proteins. Further understanding of this molecular machine will ult
Autor:
Peter Panus, Bertram G. Katzung, Erin E. Jobst, Suzanne Tinsley, Susan B. Masters, Anthony J. Trevor
The first pharmacology book for physical therapists written by physical therapists and PhD pharmacologists A Doody's Core Title for 2011! Based on the classic Katzung's Basic and Clinical Pharmacology, this ground-breaking book illuminates the ever-e
Autor:
Haidong Xu, Achilles Dugaiczyk, Guy diSibio, Richard M. Myers, Jahan Dadgar, Susan B. Masters, Gregg G. Magrane, Kristen A. Smith, David B. Lang, David W. Cox, Richard D. Goold
Publikováno v:
Human molecular genetics. 2(8)
As part of our efforts to construct a high-resolution physical map of human chromosome 4, we developed a systematic approach for efficiently generating large numbers of chromosome-specific sequence-tagged sites (STSs). In this paper, we describe how
Publikováno v:
Proteins: Structure, Function, and Genetics. 6:222-230
The functions of G proteins--like those of bacterial elongation factor (EF) Tu and the 21 kDa ras proteins (p21ras)--depend upon their abilities to bind and hydrolyze GTP and to assume different conformations in GTP- and GDP-bound states. Similaritie
Publikováno v:
Nature. 334:712-715
Membrane-bound G proteins carry information from receptors on the outside of cells to effector proteins inside cells. The alpha subunits of these heterotrimeric proteins bind and hydrolyse GTP and control the specificity of interactions with receptor
Autor:
Fred Chang, Henry R. Bourne, M. H. Chi, Barry Beiderman, Richard T Miller, Susan B. Masters, Ninfa G. Lopez
Publikováno v:
Journal of Biological Chemistry. 264:15467-15474
Mutational replacements of specific residues in the GTP-binding pocket of the 21-kDa ras proteins (p21ras) reduce their GTPase activity. To test the possibility that the cognate regions of G protein α chains participate in GTP binding and hydrolysis
Autor:
Henry R. Bourne, Arthur D. Levinson, Kathleen A. Sullivan, Susan B. Masters, Yu-Chien Liao, Barry Beiderman, Fu-Hsiung Chang, Azadeh Alborzi
Publikováno v:
Proceedings of the National Academy of Sciences. 83:6687-6691
The G protein family of signal transducers includes five heterotrimers, which are most clearly distinguished by their different alpha chains. The family includes Gs and Gi, the stimulatory and inhibitory GTP-binding regulators of adenylate cyclase; G
Publikováno v:
"Protein Engineering, Design and Selection". 1:47-54
The G proteins transduce hormonal and other signals into regulation of enzymes such as adenylyl cyclase and retinal cGMP phosphodiesterase. Each G protein contains an alpha subunit that binds and hydrolyzes guanine nucleotides and interacts with beta
Autor:
Henry R. Bourne, Warren Heideman, Barry Beiderman, Kathleen A. Sullivan, R. Tyler Miller, Susan B. Masters
Publikováno v:
Nature. 330:758-760
The mammalian G proteins transduce information from extracellular signals, including neurotransmitters, hormones and sensory stimuli, into regulation of effector enzymes or ion channels within cells. Triggered by appropriate extracellular signals, re