Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Susan B. Horwitz"'
Autor:
Sridhar Mani, Susan B. Horwitz, Gary Goldberg, Hayley McDaid, W. Griffith Humphreys, Carrie Xu, Donglu Zhang, Van T. Ly, Adriana Comprelli, Lisa Iacono, David Jayabalan, François André, Lionel Perrin, S. Nilgün Çömezoglu, Marvin Cohen, Sanjay Goel
Supplementary Data from The Effect of Ketoconazole on the Pharmacokinetics and Pharmacodynamics of Ixabepilone: A First in Class Epothilone B Analogue in Late-Phase Clinical Development
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::699687c0c30295f2d1de845abad7ce93
https://doi.org/10.1158/1078-0432.22439589
https://doi.org/10.1158/1078-0432.22439589
Autor:
Sridhar Mani, Susan B. Horwitz, Gary Goldberg, Hayley McDaid, W. Griffith Humphreys, Carrie Xu, Donglu Zhang, Van T. Ly, Adriana Comprelli, Lisa Iacono, David Jayabalan, François André, Lionel Perrin, S. Nilgün Çömezoglu, Marvin Cohen, Sanjay Goel
Purpose: To determine if ixabepilone is a substrate for cytochrome P450 3A4 (CYP3A4) and if its metabolism by this cytochrome is clinically important, we did a clinical drug interaction study in humans using ketoconazole as an inhibitor of CYP3A4.Exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::859f1d308bd5da29c4621d29624d656f
https://doi.org/10.1158/1078-0432.c.6517026
https://doi.org/10.1158/1078-0432.c.6517026
Autor:
Hong Lin, Susan B. Horwitz, Yongbiao Guan, William P. Tong, Lifeng He, Samuel J. Danishefsky, Mark D. Chappell, Jon T. Njardarson, Ting-Chao Chou, Kaustav Biswas
Publikováno v:
Journal of the American Chemical Society. 124:9825-9832
A concise modular laboratory construction of the epothilone class of promising antitumor agents has been accomplished. For the first time in the epothilone area, the new synthesis exploits the power of ring-closing olefin metathesis (RCM) in a stereo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c94cb044e1055c0571e51172fb0ea9ab
https://doi.org/10.1021/ja0262333
https://doi.org/10.1021/ja0262333
Autor:
Subrata Chakravarty, Peter W. Glunz, Iwao Ojima, Susan B. Horwitz, Lifeng He, Samuel J. Danishefsky, Ting-Chao Chou
Publikováno v:
Tetrahedron Letters. 40:6895-6898
The title compound retains some of the affinity for microtubule assemblies as does 12,13-desoxyepothilone B.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d397e65d054a05bc96abf64d325e451
https://doi.org/10.1016/s0040-4039(99)01433-1
https://doi.org/10.1016/s0040-4039(99)01433-1
Autor:
Dai Shi Su, Lifeng He, Susan B. Horwitz, Yu Huang Zheng, Erik J. Sorensen, Peter Bertinato, Samuel J. Danishefsky, Aaron Balog, Dongfang Meng, Ting-Chao Chou
Publikováno v:
Tetrahedron Letters. 38:4529-4532
The title compounds have been synthesized in a convergent way by recourse to a Weiler type dianion construction.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34fd09ea3792de9ba8fefd2d165e5da7
https://doi.org/10.1016/s0040-4039(97)00931-3
https://doi.org/10.1016/s0040-4039(97)00931-3
Autor:
Erik J. Sorensen, Yu Huang Zheng, Dai Shi Su, Ting-Chao Chou, Dongfang Meng, Aaron Balog, Susan B. Horwitz, Samuel J. Danishefsky, Lifeng He, Peter Bertinato
Publikováno v:
ChemInform. 28
The title compounds have been synthesized in a convergent way by recourse to a Weiler type dianion construction.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b09ce5f817ed4450625f5c05df0638b
https://doi.org/10.1002/chin.199740289
https://doi.org/10.1002/chin.199740289
Autor:
Iwao Ojima, Peter W. Glunz, Susan B. Horwitz, Subrata Chakravarty, Ting-Chao Chou, Lifeng He, Samuel J. Danishefsky
Publikováno v:
ChemInform. 30
The title compound retains some of the affinity for microtubule assemblies as does 12,13-desoxyepothilone B.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd8a15a2c7a49a16c76aeec358bf88d0
https://doi.org/10.1002/chin.199947246
https://doi.org/10.1002/chin.199947246
Autor:
Ting-Chao Chou, Jon T. Njardarson, Samuel J. Danishefsky, William P. Tong, Kaustav Biswas, Hong Lin, Susan B. Horwitz, Yongbiao Guan, Lifeng He, Mark D. Chappell
Publikováno v:
ChemInform. 33
A concise modular laboratory construction of the epothilone class of promising antitumor agents has been accomplished. For the first time in the epothilone area, the new synthesis exploits the power of ring-closing olefin metathesis (RCM) in a stereo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c8a4e4641069ce24c126e4e822c9899
https://doi.org/10.1002/chin.200252224
https://doi.org/10.1002/chin.200252224
Autor:
Iwao Ojima, Scott D. Kuduk, Subrata Chakravarty, Songnian Lin, Tao Wang, Xudong Geng, Michael L. Miller, Pierre-Yves Bounaud, Evelyne Michaud, Young Hoon Park, Chung-Ming Sun, John C. Slater, Tadashi Inoue, Christopher P. Borella, John J. Walsh, Ralph J. Bernacki, Paula Pera, Jean M. Veith, Ezio Bombardelli, Antonella Riva, Srinivasa Rao, Lifeng He, George A. Orr, Susan B. Horwitz, Samuel J. Danishefsky, Giovanni Scambia, Cristiano Ferlini
Publikováno v:
Anticancer Agents ISBN: 9780841237452
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be8974bfb5055ff710022096a837149e
https://doi.org/10.1021/bk-2001-0796.ch004
https://doi.org/10.1021/bk-2001-0796.ch004
Autor:
Iwao Ojima, Jin Chen, Liang Sun, Christopher P. Borella, Tao Wang, Michael L. Miller, Songnian Lin, Xudong Geng, Larisa Kuznetsova, Chuanxing Qu, David Gallager, Xianrui Zhao, Ilaria Zanardi, Shujun Xia, Susan B. Horwitz, Jon Mallen-St. Clair, Jennifer L. Guerriero, Dafna Bar-Sagi, Jean M. Veith, Paula Pera
Publikováno v:
Journal of Medicinal Chemistry; May2008, Vol. 51 Issue 11, p3203-3221, 19p