Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Susan B Morris"'
Autor:
Srikanth Elesela, Susan B Morris, Samanthi Narayanan, Surinder Kumar, David B Lombard, Nicholas W Lukacs
Publikováno v:
PLoS Pathogens, Vol 16, Iss 2, p e1008319 (2020)
Respiratory syncytial virus (RSV) is the major cause of lower respiratory tract infection in children worldwide. Sirtuin 1 (SIRT1), a NAD+ dependent deacetylase, has been associated with induction of autophagy, reprogramming cellular metabolism, and
Externí odkaz:
https://doaj.org/article/23a18838d5664fb290b5aa945c0eccf1
Autor:
Dennis M Lindell, Susan B Morris, Maria P White, Lara E Kallal, Phillip K Lundy, Tarek Hamouda, James R Baker, Nicholas W Lukacs
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e21823 (2011)
Respiratory syncytial virus (RSV) is a leading cause of bronchiolitis and pneumonia in young children worldwide, and no vaccine is currently available. Inactivated RSV vaccines tested in the 1960's led to vaccine-enhanced disease upon viral challenge
Externí odkaz:
https://doaj.org/article/f008687264364adbb8c84850382ac8a9
Autor:
Nobuhiro Asai, Alexander D. Ethridge, Wendy Fonseca, Kazuma Yagi, Andrew J. Rasky, Susan B. Morris, Nicole R. Falkowski, Yvonne J. Huang, Gary B. Huffnagle, Nicholas W. Lukacs
Publikováno v:
Physiological Reports, Vol 11, Iss 13, Pp n/a-n/a (2023)
Abstract The pathogenesis of asthma has been partially linked to lung and gut microbiome. We utilized a steroid‐resistant chronic model of cockroach antigen‐induced (CRA) asthma with corticosteroid (fluticasone) treatment to examine lung and gut
Externí odkaz:
https://doaj.org/article/30e8a75ff6d64684a97b715c7d4cd382
Autor:
Teresa L. Steininger, Murray W. Johns, D. Menno, Abby Chen, Judi Profant, Y. Grace Wang, Jed Black, Susan B. Morris
Publikováno v:
Sleep Medicine. 89:78-84
The Epworth Sleepiness Scale for Children and Adolescents (ESS-CHAD) measures daytime sleepiness, but had not previously been validated in children12 years of age.Data from a sodium oxybate (SXB) study in pediatric participants with narcolepsy with c
Publikováno v:
Sleep & Breathing = Schlaf & Atmung
Purpose This study estimated thresholds for clinically important responses and minimally important differences for two indicators of improvement for the 10-item version of the functional outcomes of sleep questionnaire (FOSQ-10). Methods Participants
Autor:
Antonia P. Popova, Charles F. Schuler, Tracy X. Cui, Andrew J. Rasky, Nicholas W. Lukacs, Carrie-Anne Malinczak, Shannon K.K. Best, Wendy Fonseca, Susan B. Morris
Publikováno v:
Mucosal immunology
Respiratory syncytial virus (RSV) infects a majority of infants and can cause severe disease leading to increased risk to develop asthma later in life. In the present studies we detected high levels of uric acid pathway components during RSV infectio
Autor:
Lev Eldemir, Danielle Hyman, Nell J Marshall, Benjamin D. Fox, James E. Doherty, Mai Ka Ying Vang, Jessica Schroeder, Susan B. Morris, Ragy Saad, Gregory Parks, Jerry Zhang, Sairam Parthasarathy
Publikováno v:
BMJ Open Respiratory Research, Vol 8, Iss Suppl 1 (2021)
Introduction Excessive daytime sleepiness (EDS) persists in some positive airway pressure (PAP)-treated patients with obstructive sleep apnoea (OSA). This study examined prevalence and severity of EDS in a real-world population with OSA to understand
Autor:
D. Menno, Kimberly Babson, Jed Black, Michelle G. Baladi, Danielle Hyman, Susan B. Morris, Russell Rosenberg
Publikováno v:
Journal of Sleep Research. 31
The present analysis examined the test-retest reliability of the Epworth Sleepiness Scale in participants with excessive daytime sleepiness associated with narcolepsy or obstructive sleep apnea in three clinical trials. Intraclass correlation coeffic
Autor:
Matthew Schaller, Susan B. Morris, Cory M. Hogaboam, David M. Habiel, Martin Phillips, Andrew J. Rasky, Steven L. Kunkel, Sem H. Phan, Bethany B. Moore, Nicholas W. Lukacs
Publikováno v:
Am J Physiol Lung Cell Mol Physiol
Stem cell factor (SCF) and its receptor c-kit have been implicated in inflammation, tissue remodeling, and fibrosis. Ingenuity Integrated Pathway Analysis of gene expression array data sets showed an upregulation of SCF transcripts in idiopathic pulm
Autor:
Catherine Ptaschinski, Ronald M. Allen, Nicholas W. Lukacs, Carrie-Anne Malinczak, Susan B. Morris, Wendy Fonseca, Andrew J. Rasky, Matthew A. Schaller
Publikováno v:
The Journal of Immunology. 204:159-168
Severe disease following respiratory syncytial virus (RSV) infection has been linked to enhanced proinflammatory cytokine production that promotes a Th2-type immune environment. Epigenetic regulation in immune cells following viral infection plays a