Histological phenotypic subtypes predict recurrence risk and response to adjuvant chemotherapy in patients with stage III colorectal cancer

Autor: Antonia K Roseweir, James H Park, Sanne ten Hoorn, Arfon GMT Powell, Susan Aherne, Campbell SD Roxburgh, Donald C McMillan, Paul G Horgan, Elizabeth Ryan, Kieran Sheahan, Louis Vermeulen, James Paul, Andrea Harkin, Janet Graham, Owen Sansom, David N Church, Ian Tomlinson, Mark Saunders, Tim J Iveson, Joanne Edwards

Publikováno v: The Journal of Pathology: Clinical Research, Vol 6, Iss 4, Pp 283-296 (2020)

Abstract Histological ‘phenotypic subtypes’ that classify patients into four groups (immune, canonical, latent and stromal) have previously been demonstrated to stratify survival in a stage I–III colorectal cancer (CRC) pilot cohort. However, c

Externí odkaz: https://doaj.org/article/86ccccce88334b4890153382c13043e0

Improving tumor budding reporting in colorectal cancer: a Delphi consensus study

Autor: Kieran Sheahan, Tine Plato Kuhlmann, John-Melle Bokhorst, Sanjay Kakar, Iris D. Nagtegaal, Jeroen van der Laak, Miriam Cuatrecasas, Inti Zlobec, Richard Kirsch, Robert H. Riddell, Susan Aherne, Ari Ristimäki, Valeria Barresi, Alessandro Lugli, Hala El-Zimaity, Jean-François Fléjou, David Gibbons, Darren Treanor, Michael Vieth, Scarlet Brockmoeller, Gieri Cathomas, Benoit Terris, Maurice B Loughrey, Tariq Sami Haddad, Cord Langner, Femke Simmer

Publikováno v: Virchows Archiv, 479, 3, pp. 459-469
Virchows Archiv
Virchows Archiv, Springer Verlag, 2021, 479 (3), pp.459-469. ⟨10.1007/s00428-021-03059-9⟩
Haddad, T S, Lugli, A, Aherne, S, Barresi, V, Terris, B, Bokhorst, J M, Brockmoeller, S F, Cuatrecasas, M, Simmer, F, El-Zimaity, H, Fléjou, J F, Gibbons, D, Cathomas, G, Kirsch, R, Kuhlmann, T P, Langner, C, Loughrey, M B, Riddell, R, Ristimäki, A, Kakar, S, Sheahan, K, Treanor, D, van der Laak, J, Vieth, M, Zlobec, I & Nagtegaal, I D 2021, ' Improving tumor budding reporting in colorectal cancer : a Delphi consensus study ', Virchows Archiv, vol. 479, no. 3, pp. 459-469 . https://doi.org/10.1007/s00428-021-03059-9
Haddad, Tariq Sami; Lugli, Alessandro; Aherne, Susan; Barresi, Valeria; Terris, Benoît; Bokhorst, John-Melle; Brockmoeller, Scarlet Fiona; Cuatrecasas, Miriam; Simmer, Femke; El-Zimaity, Hala; Fléjou, Jean-François; Gibbons, David; Cathomas, Gieri; Kirsch, Richard; Kuhlmann, Tine Plato; Langner, Cord; Loughrey, Maurice B; Riddell, Robert; Ristimäki, Ari; Kakar, Sanjay; ... (2021). Improving tumor budding reporting in colorectal cancer: a Delphi consensus study. Virchows Archiv, 479(3), pp. 459-469. Springer 10.1007/s00428-021-03059-9
Virchows Archiv, 479, 459-469

Tumor budding is a long-established independent adverse prognostic marker in colorectal cancer, yet methods for its assessment have varied widely. In an effort to standardize its reporting, a group of experts met in Bern, Switzerland, in 2016 to reac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1aa42f69b747e03ac80ea6081993ade5

Prognostic phenotypic subtypes to predict recurrence and response to adjuvant chemotherapy for colorectal cancer

Autor: Timothy Iveson, Arfon Powell, Joanne Edwards, Campbell S.D. Roxburgh, Louis Vermeulen, Owen J. Sansom, Janet Graham, James Paul, Keiran Sheahan, Donald C. McMillan, Paul G. Horgan, Antonia K. Roseweir, James H. Park, Sanne ten Hoorn, David N. Church, Susan Aherne, Elizabeth J. Ryan

Publikováno v: Journal of Clinical Oncology. 38:205-205

205 Background: Histological phenotypic subtypes have been proposed that stratify survival in a discovery cohort of patients with stage I-III colorectal cancer (CRC). However, clinical utility has not been validated nor associations with recurrence a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1ec10217638de14d531ba188a23fa410
https://doi.org/10.1200/jco.2020.38.4_suppl.205

Malignant peripheral nerve sheath tumour of the bladder associated with neurofibromatosis I

Autor: J. O’Brien, Susan Aherne, W C Torreggiani, Padraig Daly, Orla Buckley

Publikováno v: Canadian Urological Association Journal. 2:637

Neurofibromatosis is a hamartomatous disorder of autonomic peripheral nerve sheaths associated with peripheral nerve sheath tumours. Most tumours are neurofibromas; however, the genitourinary system is rarely involved. We present a rare case of a ner

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b5259da169def5f2d47631b059469fe
https://doi.org/10.5489/cuaj.985