Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Susan A. Willavize"'
Publikováno v:
The Journal of Clinical Pharmacology. 57:255-265
Population pharmacokinetic models for armodafinil and its major metabolites, R-modafinil acid and modafinil sulfone, were developed, and selected covariates were investigated. Data from 583 healthy subjects and patients with bipolar I disorder in 11
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ed48cb062b1127da27feb261173fc28
https://doi.org/10.1002/jcph.800
https://doi.org/10.1002/jcph.800
Autor:
David J. Clark, Susan A. Willavize, Timothy G. Brayman, Melissa O'Gorman, G. Scott Grover, R. Scott Obach, Robert L. Walsky, Hélène M. Faessel, Aaron H. Burstein
Publikováno v:
The Journal of Clinical Pharmacology. 47:1421-1429
This study investigated the effect of varenicline on the pharmacokinetics and pharmacodynamics of a single dose of warfarin in 24 adult smokers and compared these findings with data generated using human in vitro systems. Subjects were randomized to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a6870e0c8a67e58f7f2e50f5de396ad
https://doi.org/10.1177/0091270007307574
https://doi.org/10.1177/0091270007307574
Autor:
Lisa C. Dogolo, Stuart I. Harris, John Vincent, Susan A. Willavize, George H Foulds, Hylar L Friedman
Publikováno v:
British Journal of Clinical Pharmacology. 50:455-463
Aims To determine whether repeated once daily administration of grapefruit juice altered the pharmacokinetics or pharmacodynamics of the calcium antagonist amlodipine. Methods The effects of grapefruit juice on the pharmacokinetics and pharmacodynami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::682227cf78445b0cb28b8f68e45ea9bd
https://doi.org/10.1046/j.1365-2125.2000.00283.x
https://doi.org/10.1046/j.1365-2125.2000.00283.x
Publikováno v:
The American Journal of Surgery. 176:23S-26S
Background Patients in the hospital, as well as those in home care settings, often require nutritional supplementation with enteral feeding solutions. In addition, patients with serious infections who are clinically unstable often cannot maintain ade
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e16df5490e7684954a8b42dab83a050
https://doi.org/10.1016/s0002-9610(98)00216-5
https://doi.org/10.1016/s0002-9610(98)00216-5
Publikováno v:
The American Journal of Surgery. 176:32S-38S
Background: Morphine and antibiotics are frequently coadministered in the surgical setting. These agents may interact, reducing the efficacy of the antibiotic or increasing the toxicity of morphine. It is therefore important to determine whether anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c244879a28a21a6ca81b235ca4bcbff7
https://doi.org/10.1016/s0002-9610(98)00218-9
https://doi.org/10.1016/s0002-9610(98)00218-9
Publikováno v:
Journal of Antimicrobial Chemotherapy. 39:87-92
Two studies determined the oral bioavailability of trovafloxacin (CP-99,219) in healthy volunteers under fasted and fed conditions. In a randomized, two-way crossover study, 12 fasting subjects received two 100 mg tablets of trovafloxacin and an equi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ae7c701b57db58d17d1d511f3a3158c
https://doi.org/10.1093/jac/39.suppl_2.87
https://doi.org/10.1093/jac/39.suppl_2.87
Autor:
R J Polzer, Renli Teng, Susan A. Willavize, Hylar L Friedman, B. A. Baris, J Venitz, John Vincent
Publikováno v:
Journal of Antimicrobial Chemotherapy. 39:75-80
Fifteen healthy male volunteers (in four groups) received single 1 h i.v. infusions of alatrofloxacin (CP-116,517) equivalent to 30, 100, 200 or 300 mg of its active metabolite, trovafloxacin (CP-99,219). Blood and urine were sampled over 73 and 72 h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::057cb4ac1c8de561cbc60b45f05ea8a4
https://doi.org/10.1093/jac/39.suppl_2.75
https://doi.org/10.1093/jac/39.suppl_2.75
Publikováno v:
Alzheimer's & Dementia. 5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80341c07c521ab545a18f9cda9d02e2d
https://doi.org/10.1016/j.jalz.2009.04.269
https://doi.org/10.1016/j.jalz.2009.04.269
Publikováno v:
Pharmaceutical Research. :154-160
A validation procedure is presented that satisfies the FDA requirements of accuracy (including precision repeatability), sensitivity, linearity, dynamic range, and homoscedasticity, all with a single set of data. The procedure utilizes the corrigible
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a236c2ef651d12138ddcc51682269809
https://doi.org/10.1023/a:1015876718419
https://doi.org/10.1023/a:1015876718419
Autor:
Aaron H, Burstein, David J, Clark, Melissa, O'Gorman, Susan A, Willavize, Timothy G, Brayman, G Scott, Grover, Robert L, Walsky, R Scott, Obach, Hélène M, Faessel
Publikováno v:
Journal of clinical pharmacology. 47(11)
This study investigated the effect of varenicline on the pharmacokinetics and pharmacodynamics of a single dose of warfarin in 24 adult smokers and compared these findings with data generated using human in vitro systems. Subjects were randomized to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bcc0b1a4884820695d0f62721337d4ca
https://pubmed.ncbi.nlm.nih.gov/17962429
https://pubmed.ncbi.nlm.nih.gov/17962429