Zobrazeno 1 - 10
of 228
pro vyhledávání: '"Susan A. Logan"'
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Ruff et al. demonstrate that phosphorylation of the androgen receptor and 14-3-3 ζ by PIM1 kinase coordinates their interaction and chromatin occupancy at genes involved in cell migration and invasion. The authors conclude that PIM1 phosphorylation
Externí odkaz:
https://doaj.org/article/ce22aa667a154da3a0f3b5da39b70bd0
Autor:
Erica M. Briggs, Paolo Mita, Xiaoji Sun, Susan Ha, Nikita Vasilyev, Zev R. Leopold, Evgeny Nudler, Jef D. Boeke, Susan K. Logan
Publikováno v:
Mobile DNA, Vol 12, Iss 1, Pp 1-12 (2021)
Abstract Background The autonomous retroelement Long Interspersed Element-1 (LINE-1) mobilizes though a copy and paste mechanism using an RNA intermediate (retrotransposition). Throughout human evolution, around 500,000 LINE-1 sequences have accumula
Externí odkaz:
https://doaj.org/article/2c29121cadcf4aef9e4d4b3515f43dda
Publikováno v:
Mobile DNA, Vol 12, Iss 1, Pp 1-13 (2021)
Abstract Background Long INterspersed Element-1 (LINE-1) is an autonomous retroelement able to “copy-and-paste” itself into new loci of the host genome through a process called retrotransposition. The LINE-1 bicistronic mRNA codes for two protein
Externí odkaz:
https://doaj.org/article/86bc85fe67f342998a10702c72579a23
Autor:
Russell J. Ledet, Sophie E. Ruff, Yu Wang, Shruti Nayak, Jeffrey A. Schneider, Beatrix Ueberheide, Susan K. Logan, Michael J. Garabedian
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
Through a chemical genetics screen and phospho-proteomics, Ledet and Ruff et al identify substrates of the oncogenic kinase PIM1 in prostate cancer cells. They find that NDRG1 protein is destabilized by PIM1-mediated phosphorylation to reduce its met
Externí odkaz:
https://doaj.org/article/80eaf72f1a91430f8ee15122bdc18eb3
Publikováno v:
Mobile DNA, Vol 10, Iss 1, Pp 1-6 (2019)
Abstract Background We previously examined expression of Long Interspersed Element-1 (LINE-1) in a variety of prostate cancer cells including hormone-dependent LNCaP cells. These studies demonstrated expression and sub-cellular localization of LINE-1
Externí odkaz:
https://doaj.org/article/5d8064dcde444dbd8f4d1b582f9119c2
Autor:
Jeffrey A. Schneider, Timothy W. Craven, Amanda C. Kasper, Chi Yun, Michael Haugbro, Erica M. Briggs, Vladimir Svetlov, Evgeny Nudler, Holger Knaut, Richard Bonneau, Michael J. Garabedian, Kent Kirshenbaum, Susan K. Logan
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Small molecules and peptide inhibitors have their benefits and faults when it comes to inhibiting protein-protein interactions. Here, the authors designed a peptoid-peptide hybrid that inhibited β-catenin/TCF interactions, leading to inhibition of W
Externí odkaz:
https://doaj.org/article/3c5aea308e6d452390e2d44fcb37b64b
Autor:
Erica M. Briggs, Susan Ha, Paolo Mita, Gregory Brittingham, Ilaria Sciamanna, Corrado Spadafora, Susan K. Logan
Publikováno v:
Mobile DNA, Vol 9, Iss 1, Pp 1-9 (2018)
Abstract Background Long Interspersed Nuclear Element-1 (LINE-1) is an autonomous retrotransposon that generates new genomic insertions through the retrotransposition of a RNA intermediate. Expression of LINE-1 is tightly repressed in most somatic ti
Externí odkaz:
https://doaj.org/article/d86b1490718f496da697ddf3daffc4df
Publikováno v:
Glycobiology. 32:629-644
The glycosylation of structural proteins is a widespread posttranslational modification in Archaea. Although only a handful of archaeal N-glycan structures have been determined to date, it is evident that the diversity of structures expressed is grea
Autor:
Sarah W. Li, Matthew W. Kemp, Susan J.S. Logan, Pooja Sharma Dimri, Navkaran Singh, Citra N.Z. Mattar, Pradip Dashraath, Harshaana Ramlal, Aniza P. Mahyuddin, Suren Kanayan, Sean W.D. Carter, Serene P.T. Thain, Erin L. Fee, Sebastian E. Illanes, Mahesh A. Choolani, Mary Rauff, Arijit Biswas, Jeffrey J.H. Low, Joseph S. Ng, Arundhati T. Gosavi, Zhongwei Huang, Preethi Rajendran, Kwok Weng Roy Ng, Jeslyn J.L. Wong, Grace M.F. Chan, Kelvin Zhi Xing Lee, Jeannie J.Y. Yap, Nurulhuda Ahmad, Shwetha Shanmugam, Rajeswari Kathirvel, Manisha Mathur, Whui Whui Lim, Min Yu Lim
Publikováno v:
American Journal of Obstetrics and Gynecology.
Autor:
Gregory David, Susan K. Logan, David J. Cantor, Peng Lee, Yu Wang, Fang-Ming Deng, Anthony J. Bainor
This file contains the figure legends for each of the supplementary figures 1-5. Figure S1: Deletion of Sin3b does not impair loss of PTEN-driven AKT activation in the prostate anterior lobe. IHC stainings for SIN3B, PTEN, and pAKT of the anterior lo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dca0c20186cc1e378ff2790a23c238c
https://doi.org/10.1158/0008-5472.22414610
https://doi.org/10.1158/0008-5472.22414610