Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Susan A. Chrysogelos"'
Publikováno v:
Journal of Cellular Biochemistry. 80:538-549
Hormone-independent human breast cancer is characterized by estrogen receptor (ER) loss and the acquisition of high epidermal growth factor receptor (EGFR) levels. Despite the tendency for an inverse correlation between EGFR and ER, EGFR is a strong
Publikováno v:
Journal of Cellular Biochemistry. 81:232-246
Epidermal growth factor receptor (EGFR) is a transmembrane receptor whose overexpression in breast cancer predicts for poor prognosis and is inversely correlated with expression of estrogen receptor (ER). This study was designed to investigate whethe
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 59:261-269
To investigate the molecular mechanisms underlying the two- to three-fold induction of human transforming growth factor-alpha (hTGF-alpha) mRNA and two- to five-fold induction of hTGF-alpha protein observed following estrogen treatment of hormone-res
Publikováno v:
Breast Cancer Research and Treatment. 29:29-40
Epidermal growth factor receptor (EGFR) overexpression correlates with both loss of estrogen receptor (ER) and poor prognosis in breast cancer. Interestingly, in normal breast EGFR appears to be expressed more frequently than in malignant tissue, and
Autor:
Susan A. Chrysogelos
Publikováno v:
Nucleic Acids Research. 21:5736-5741
The chromatin structure of the epidermal growth factor receptor gene (EGFR) has been analyzed in several human breast cancer cell lines exhibiting a wide range of EGFR expression. Using DNase I, structural differences were identified in the promoter,
Publikováno v:
Journal of molecular endocrinology. 35(1)
Reduction of epidermal growth factor receptor (EGFR) mRNA and protein by 1,25-dihydroxyvitamin D3 has been documented in MCF7, T47D, and BT549 breast cancer cells. In the present report, functional mapping of the EGFR promoter in BT549 cells has reve
Publikováno v:
Breast cancer research and treatment. 86(1)
The effect of 1,25-dihydroxyvitamin D(3), analog C (1,25-(OH)(2)-16-en-23-yn-26,27-F(6)-vitamin D(3)), 9-cis retinoic acid, and all-trans retinoic acid on the growth and expression of EGFR in MCF7, T47D, BT474, and BT549 breast cancer cells was exami
Publikováno v:
Journal of cellular biochemistry. 85(3)
The epidermal growth factor receptor (EGFR) exhibits an inverse correlation with estrogen receptor (ER) expression in the majority of breast cancers, predicting a poor response to endocrine therapy and poor survival rate. Inappropriate overexpression
Autor:
James N. Welch, Susan A. Chrysogelos
Publikováno v:
The Molecular Basis of Human Cancer ISBN: 9781617371073
Cancer is not a single disease, but a collection of diseases all of which are related by a common root cause: the loss of controlled cell growth. Cancer begins as a clonal disease, that is, it stems from the genetic corruption of a single cell. This
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85c2d5ec6306262348851c5688cbc63f
https://doi.org/10.1007/978-1-59259-125-1_4
https://doi.org/10.1007/978-1-59259-125-1_4
Hormone independent human breast cancer is characterized by estrogen receptor (ER) loss and the acquisition of high epidermal growth factor receptor (EGFR)levels. Despite the tendency for an inverse correlation between EGFR and ER, EGFR is a strong p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3b6d7f81b88774f6f8014b3a98d7030
https://doi.org/10.21236/adb238010
https://doi.org/10.21236/adb238010