Zobrazeno 1 - 10
of 169
pro vyhledávání: '"Susan, Richter"'
Autor:
Sara Mellid, Eduardo Gil, Rocío Letón, Eduardo Caleiras, Emiliano Honrado, Susan Richter, Nuria Palacios, Marcos Lahera, Juan C. Galofré, Adriá López-Fernández, Maria Calatayud, Aura D. Herrera-Martínez, María A. Galvez, Xavier Matias-Guiu, Milagros Balbín, Esther Korpershoek, Eugénie S. Lim, Francesca Maletta, Sofia Lider, Stephanie M. J. Fliedner, Nicole Bechmann, Graeme Eisenhofer, Letizia Canu, Elena Rapizzi, Irina Bancos, Mercedes Robledo, Alberto Cascón
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2023)
IntroductionThe percentage of patients diagnosed with pheochromocytoma and paraganglioma (altogether PPGL) carrying known germline mutations in one of the over fifteen susceptibility genes identified to date has dramatically increased during the last
Externí odkaz:
https://doaj.org/article/c4c5fc8413084893a0bdc6df97e44790
Publikováno v:
ACS Omega, Vol 4, Iss 26, Pp 22101-22107 (2019)
Externí odkaz:
https://doaj.org/article/02f6a00c91a34e0dba95b5648ebd79fe
Autor:
Florian Brandt, Martin Ullrich, Verena Seifert, Cathleen Haase-Kohn, Susan Richter, Torsten Kniess, Jens Pietzsch, Markus Laube
Publikováno v:
Molecules, Vol 27, Iss 19, p 6587 (2022)
COX-2 can be considered as a clinically relevant molecular target for adjuvant, in particular radiosensitizing treatments. In this regard, using selective COX-2 inhibitors, e.g., in combination with radiotherapy or endoradiotherapy, represents an int
Externí odkaz:
https://doaj.org/article/38ca741a608c40b5bcf78eb667e540d0
Autor:
Nikolaos G. Bliziotis, Leo A. J. Kluijtmans, Gerjen H. Tinnevelt, Parminder Reel, Smarti Reel, Katharina Langton, Mercedes Robledo, Christina Pamporaki, Alessio Pecori, Josie Van Kralingen, Martina Tetti, Udo F. H. Engelke, Zoran Erlic, Jasper Engel, Timo Deutschbein, Svenja Nölting, Aleksander Prejbisz, Susan Richter, Jerzy Adamski, Andrzej Januszewicz, Filippo Ceccato, Carla Scaroni, Michael C. Dennedy, Tracy A. Williams, Livia Lenzini, Anne-Paule Gimenez-Roqueplo, Eleanor Davies, Martin Fassnacht, Hanna Remde, Graeme Eisenhofer, Felix Beuschlein, Matthias Kroiss, Emily Jefferson, Maria-Christina Zennaro, Ron A. Wevers, Jeroen J. Jansen, Jaap Deinum, Henri J. L. M. Timmers
Publikováno v:
Metabolites, Vol 12, Iss 8, p 679 (2022)
Despite considerable morbidity and mortality, numerous cases of endocrine hypertension (EHT) forms, including primary aldosteronism (PA), pheochromocytoma and functional paraganglioma (PPGL), and Cushing’s syndrome (CS), remain undetected. We aimed
Externí odkaz:
https://doaj.org/article/abff7db4cbcd43ff877f5cefe5971e51
Autor:
Maximilian Clausing, Doreen William, Matthias Preussler, Julia Biedermann, Konrad Grützmann, Susan Richter, Frank Buchholz, Achim Temme, Evelin Schröck, Barbara Klink
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 10, p 5787 (2022)
The IDH1R132H mutation in glioma results in the neoenzymatic function of IDH1, leading to the production of the oncometabolite 2-hydroxyglutarate (2-HG), alterations in energy metabolism and changes in the cellular redox household. Although shifts in
Externí odkaz:
https://doaj.org/article/dbab92f1357e48c5aec886d403421274
Autor:
Dieter M. Matlac, Katerina Hadrava Vanova, Nicole Bechmann, Susan Richter, Julica Folberth, Hans K. Ghayee, Guang-Bo Ge, Luma Abunimer, Robert Wesley, Redouane Aherrahrou, Margo Dona, Ángel M. Martínez-Montes, Bruna Calsina, Maria J. Merino, Markus Schwaninger, Peter M. T. Deen, Zhengping Zhuang, Jiri Neuzil, Karel Pacak, Hendrik Lehnert, Stephanie M. J. Fliedner
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Paragangliomas and pheochromocytomas (PPGLs) are chromaffin tumors associated with severe catecholamine-induced morbidities. Surgical removal is often curative. However, complete resection may not be an option for patients with succinate dehydrogenas
Externí odkaz:
https://doaj.org/article/341f1888ed96433699e71d363cd1e7e4
Autor:
Jana Helm, Stephan Drukewitz, Isabel Poser, Susan Richter, Markus Friedemann, Doreen William, Hermine Mohr, Svenja Nölting, Mercedes Robledo, Stefan R. Bornstein, Graeme Eisenhofer, Nicole Bechmann
Publikováno v:
Cells, Vol 11, Iss 3, p 560 (2022)
Continuous activation of hypoxia pathways in pheochromocytomas and paragangliomas (PPGLs) is associated with higher disease aggressiveness, for which effective treatment strategies are still missing. Most of the commonly used in vitro models lack cha
Externí odkaz:
https://doaj.org/article/58b6eb2931384e76a9944c7d01ef3856
Autor:
Martin Ullrich, Susan Richter, Josephine Liers, Stephan Drukewitz, Markus Friedemann, Jörg Kotzerke, Christian G. Ziegler, Svenja Nölting, Klaus Kopka, Jens Pietzsch
Publikováno v:
Theranostics 13(2023)1, 278-294
Pheochromocytomas and paragangliomas (PCCs/PGLs) are catecholamine-producing tumors. In inoperable and metastatic cases, somatostatin type 2 receptor (SSTR2) expression allows for peptide receptor radionuclide therapy with [177Lu]Lu-DOTA-TATE. Insuff
Autor:
Minghao Li, Yazhi He, Yingxian Pang, Jing Zhang, Yu Feng, Yao He, Xiaowen Xu, Yongbao Wei, Dewen Zhong, Wanglong Deng, Long Wang, Bin Yan, Yazhuo Jiang, Ning Xu, Hai Cai, Yanlin Wen, Jinzhuo Ning, Yujun Liu, Xin Gao, Zhongyan Shan, Longfei Liu, Xiaochun Teng, Susan Richter, Jingjing Jiang
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 108:1215-1223
Context IDH1 is a pheochromocytoma/paraganglioma (PPGL) susceptibility gene; however, its role, especially in the Chinese population, has not been characterized. Objective To determine the prevalence of somatic IDH1 hotspot variants in a large cohort
Autor:
Doreen William, Kati Erdmann, Jonas Ottemöller, Anastasios Mangelis, Catleen Conrad, Mirko Peitzsch, Evelin Schröck, Graeme Eisenhofer, Aristeidis Zacharis, Susanne Füssel, Daniela Aust, Barbara Klink, Susan Richter
Publikováno v:
Metabolites, Vol 11, Iss 11, p 764 (2021)
Renal cell carcinoma (RCC) is among the 10 most common cancer entities and can be categorised into distinct subtypes by differential expression of Krebs cycle genes. We investigated the predictive value of several targeted metabolites with regards to
Externí odkaz:
https://doaj.org/article/737c8718eab247f0abc5488e82bb525a