Zobrazeno 1 - 10
of 300
pro vyhledávání: '"Susan, Morgello"'
Autor:
Patricia K. Riggs, Albert M. Anderson, Bin Tang, Leah H. Rubin, Susan Morgello, Christina M. Marra, Benjamin B. Gelman, David B. Clifford, Donald Franklin, Robert K. Heaton, Ronald J. Ellis, Christine Fennema-Notestine, Scott L. Letendre
Publikováno v:
Viruses, Vol 15, Iss 12, p 2410 (2023)
Structural brain abnormalities, including those in white matter (WM), remain common in people with HIV (PWH). Their pathogenesis is uncertain and may reflect multiple etiologies. Oxidative stress is associated with inflammation, HIV, and its comorbid
Externí odkaz:
https://doaj.org/article/674144d9abd54ab9bbe9c396f0f14767
Autor:
Jacinta Murray, Gregory Meloni, Etty P. Cortes, Ariadna KimSilva, Michelle Jacobs, Alyssa Ramkissoon, John F. Crary, Susan Morgello
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-16 (2022)
Abstract Microglia are implicated in Alzheimer’s Disease (AD) pathogenesis. In a middle-aged cohort enriched for neuroinflammation, we asked whether microgliosis was related to neocortical amyloid beta (A $$\upbeta$$ β ) deposition and neuronal ph
Externí odkaz:
https://doaj.org/article/e891ec38d32a4372807c5f7cb093fbdc
Autor:
Debjani Guha, David R. Lorenz, Vikas Misra, Sukrutha Chettimada, Susan Morgello, Dana Gabuzda
Publikováno v:
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-19 (2019)
Abstract Background Extracellular vesicles (EVs) are nano-sized particles present in most body fluids including cerebrospinal fluid (CSF). Little is known about CSF EV proteins in HIV+ individuals. Here, we characterize the CSF EV proteome in HIV+ su
Externí odkaz:
https://doaj.org/article/26c85391a3cd4ffd836fa305e9ae8ff7
Autor:
Rosiris León-Rivera, Mike Veenstra, Maribel Donoso, Elizabeth Tell, Eliseo A. Eugenin, Susan Morgello, Joan W. Berman
Publikováno v:
mBio, Vol 12, Iss 2 (2021)
We characterized mechanisms of CNS viral reservoir establishment/replenishment using peripheral blood mononuclear cells (PBMC) of PLWH on cART and propose therapeutic targets to reduce/block selective entry of cells harboring HIV (HIV +++
Externí odkaz:
https://doaj.org/article/e8af781fad4a4326b6f08d202fb4ff47
Publikováno v:
AIDS. 37:1247-1256
Autor:
David R. Lorenz, Vikas Misra, Sukrutha Chettimada, Hajime Uno, Lanqing Wang, Benjamin C. Blount, Víctor R. De Jesús, Benjamin B. Gelman, Susan Morgello, Steven M. Wolinsky, Dana Gabuzda
Publikováno v:
EClinicalMedicine, Vol 31, Iss , Pp 100697- (2021)
Background: Marijuana smoke contains some of the same toxicants present in tobacco smoke. Marijuana smoking is prevalent among HIV+ individuals, but few studies have characterized smoke-related toxicants or associated health outcomes in exclusive mar
Externí odkaz:
https://doaj.org/article/3e4ff082ad8b41bd9654f284042aaf59
Twelve-year neurocognitive decline in HIV is associated with comorbidities, not age: a CHARTER study
Autor:
Robert K Heaton, Ronald J Ellis, Bin Tang, Christina M Marra, Leah H Rubin, David B Clifford, J Allen McCutchan, Benjamin B Gelman, Susan Morgello, Donald R Franklin, Scott L Letendre
Publikováno v:
Brain : a journal of neurology, vol 146, iss 3
Brain
Brain
Modern antiretroviral therapy (ART) has increased longevity of people with HIV and shifted the age distribution of the HIV pandemic upward toward that of the general population. This positive development has also led to concerns about premature and/o
Autor:
Jessica Robinson-Papp, Varuna Astha, Alexandra Nmashie, Sandeep K. Sharma, Seunghee Kim-Schulze, Jacinta Murray, Mary Catherine George, Susan Morgello, Bridget R. Mueller, Steven A. Lawrence, Emma K.T. Benn
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 7, Iss , Pp 100112- (2020)
Purpose: HIV-associated autonomic neuropathy (HIV-AN) is common and may be associated with both sympathetic and parasympathetic dysfunction. Sympathetic nervous system (SNS) dysfunction occurs on a continuum of hyper-to hypo-adrenergic function, and
Externí odkaz:
https://doaj.org/article/7f961b0f3fda4f0ab9391f48c0d4585a
Autor:
Ronald J. Ellis, Scott L. Letendre, J. Hampton Atkinson, David Clifford, Ann C. Collier, Benjamin B. Gelman, Christina Marra, J. Allen McCutchan, Susan Morgello, Ned Sacktor, Bin Tang, Robert K. Heaton
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 7, Iss , Pp 100121- (2020)
Background and objectives: People with HIV (PWH) often suffer from depressive symptoms which have a deleterious impact on numerous domains including antiretroviral adherence and quality of life. In the general population, a treatment-resistant phenot
Externí odkaz:
https://doaj.org/article/49350f96698e4cd5b2185ce6acbafb38
Autor:
Sukrutha Chettimada, David R. Lorenz, Vikas Misra, Simon T. Dillon, R. Keith Reeves, Cordelia Manickam, Susan Morgello, Gregory D. Kirk, Shruti H. Mehta, Dana Gabuzda
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-16 (2018)
Abstract Exosomes are nanovesicles released from most cell types including immune cells. Prior studies suggest exosomes play a role in HIV pathogenesis, but little is known about exosome cargo in relation to immune responses and oxidative stress. Her
Externí odkaz:
https://doaj.org/article/b897ba8872bc48c9b7875ebc758d9ce5