Zobrazeno 1 - 10
of 180
pro vyhledávání: '"Susan, Moir"'
Autor:
M. Ali Rai, Jana Blazkova, Jesse S. Justement, Victoria Shi, Brooke D. Kennedy, Maegan R. Manning, Mary McLaughlin, Michael C. Sneller, Alice K. Pau, Susan Moir, Tae-Wook Chun
Publikováno v:
EBioMedicine, Vol 104, Iss , Pp 105151- (2024)
Summary: Background: People living with HIV (PLWH) with multidrug-resistant (MDR) viruses have limited therapeutic options and present challenges regarding clinical management. Recent studies have shown that passive transfer of combination broadly ne
Externí odkaz:
https://doaj.org/article/cf0e1cf67e494855a8394bb7836c7ac3
Autor:
Joanna Ireland, Jason Segura, Genbin Shi, Julianna Buchwald, Gwynne Roth, Thomas Juncheng Shen, Ruipeng Wang, Xinhua Ji, Elizabeth R. Fischer, Susan Moir, Tae-Wook Chun, Peter D. Sun
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
HIV-1 gp120 glycan binding to C-type lectin adhesion receptor L-selectin/CD62L on CD4 T cells facilitates viral attachment and entry. Paradoxically, the adhesion receptor impedes HIV-1 budding from infected T cells and the viral release requires the
Externí odkaz:
https://doaj.org/article/d1345b938a9e4d4b9d8558446242fdc7
Autor:
Vitaliy A. Matveev, Erik Z. Mihelic, Erika Benko, Patrick Budylowski, Sebastian Grocott, Terry Lee, Chapin S. Korosec, Karen Colwill, Henry Stephenson, Ryan Law, Lesley A. Ward, Salma Sheikh-Mohamed, Geneviève Mailhot, Melanie Delgado-Brand, Adrian Pasculescu, Jenny H. Wang, Freda Qi, Tulunay Tursun, Lela Kardava, Serena Chau, Philip Samaan, Annam Imran, Dennis C. Copertino, Jr., Gary Chao, Yoojin Choi, Robert J. Reinhard, Rupert Kaul, Jane M. Heffernan, R. Brad Jones, Tae-Wook Chun, Susan Moir, Joel Singer, Jennifer Gommerman, Anne-Claude Gingras, Colin Kovacs, Mario Ostrowski
Publikováno v:
iScience, Vol 26, Iss 10, Pp 107915- (2023)
Summary: Older individuals and people with HIV (PWH) were prioritized for COVID-19 vaccination, yet comprehensive studies of the immunogenicity of these vaccines and their effects on HIV reservoirs are not available. Our study on 68 PWH and 23 HIV-ne
Externí odkaz:
https://doaj.org/article/c0a02cfb1ee4418788ae8efa6e553405
Autor:
Akira Nishio, Sharika Hasan, Heiyoung Park, Nana Park, Jordan H. Salas, Eduardo Salinas, Lela Kardava, Paul Juneau, Nicole Frumento, Guido Massaccesi, Susan Moir, Justin R. Bailey, Arash Grakoui, Marc G. Ghany, Barbara Rehermann
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Long-term dynamics of the humoral response to HCV in cured individuals aren’t well understood. Here, Nishio et al. show that virus-neutralizing antibody levels decrease in potency and breadth after cure of chronic hepatitis C, while HCV-specific me
Externí odkaz:
https://doaj.org/article/2d4cf5245d9644afaee0f1a8317aa30a
Autor:
Felipe Lopes de Assis, Kenneth B. Hoehn, Xiaozhen Zhang, Lela Kardava, Connor D. Smith, Omar El Merhebi, Clarisa M. Buckner, Krittin Trihemasava, Wei Wang, Catherine A. Seamon, Vicky Chen, Paul Schaughency, Foo Cheung, Andrew J. Martins, Chi-I Chiang, Yuxing Li, John S. Tsang, Tae-Wook Chun, Steven H. Kleinstein, Susan Moir
Publikováno v:
Cell Reports, Vol 42, Iss 7, Pp 112780- (2023)
Summary: Protective immunity following vaccination is sustained by long-lived antibody-secreting cells and resting memory B cells (MBCs). Responses to two-dose SARS-CoV-2 mRNA-1273 vaccination are evaluated longitudinally by multimodal single-cell an
Externí odkaz:
https://doaj.org/article/0741d21fc63c4181b8b82bf41955424e
Autor:
Brooke D. Kennedy, Jana Blazkova, Jesse S. Justement, Victoria Shi, M. Ali Rai, Maegan R. Manning, Lauren Praiss, Kathleen Gittens, Paul A. Wender, Sean Patro, Xiaolin Wu, Susan Moir, Tae-Wook Chun
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 3 (2023)
Externí odkaz:
https://doaj.org/article/e547c1c06cc24ff0a2b852c649742a7e
Autor:
Jason Segura, Joanna Ireland, Zhongcheng Zou, Gwynne Roth, Julianna Buchwald, Thomas J Shen, Elizabeth Fischer, Susan Moir, Tae-Wook Chun, Peter D Sun
Publikováno v:
PLoS ONE, Vol 18, Iss 2, p e0281087 (2023)
HIV infection remains incurable to date and there are no compounds targeted at the viral release. We show here HIV viral release is not spontaneous, rather requires caspases activation and shedding of its adhesion receptor, CD62L. Blocking the caspas
Externí odkaz:
https://doaj.org/article/db16d094b4b9452b932e1d4929bc1688
Publikováno v:
Pathogens and Immunity, Vol 7, Iss 2 (2022)
Most vaccines against viral pathogens protect through the acquisition of immunological memory from long-lived plasma cells that produce antibodies and memory B cells that can rapidly respond upon an encounter with the pathogen or its variants. The CO
Externí odkaz:
https://doaj.org/article/445122e7f91949618b469f2865739df4
Autor:
Jane McEneny, Sarah-Louise Henry, Jayne Woodside, Susan Moir, Amelia Rudd, Nick Vaughan, Frank Thies
Publikováno v:
Frontiers in Nutrition, Vol 9 (2022)
BackgroundThe consumption of lycopene-rich foods may lower cardiovascular disease (CVD) risk. Lycopene circulates in the blood bound to lipoproteins, including high-density lipoproteins (HDLs). Preliminary data from our group showed that increased co
Externí odkaz:
https://doaj.org/article/7e3834204c934ff3b7872764526eac72
Autor:
Margaret H. O’Connor, Roshell Muir, Marita Chakhtoura, Michael Fang, Eirini Moysi, Susan Moir, Alison J. Carey, Alyssa Terk, Carmen N. Nichols, Talibah Metcalf, Constantinos Petrovas, Mark J. Cameron, Virginie Tardif, Elias K. Haddad
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
Margaret O’Connor et al. report a new Innate Lymphoid Cell population in human tonsils and lymph nodes that inhibit the functional interaction of follicular helper T cells and germinal center B cells. They show that this cell population is expanded
Externí odkaz:
https://doaj.org/article/a866230b1fdc4b2fb508ecc62a24397c