Can medicines development improve outcomes in asthma and chronic obstructive pulmonary disease management by driving effectiveness?

Autor: David A. Leather, Louisa Yates, Henrik Svedsater, Loretta Jacques, Susan Collier, Danielle Powell, Rupert Jones

Publikováno v: Respiratory Research, Vol 20, Iss 1, Pp 1-7 (2019)

Abstract Despite the availability of treatment guidelines and inhaled medications for asthma and chronic obstructive pulmonary disease (COPD), much remains to be done to lessen the burden of these respiratory diseases for patients. The challenge of s

Externí odkaz: https://doaj.org/article/fad5981a1177415c85b17e9e4adf2ffa

Impact of socioeconomic status on participation and outcomes in the Salford Lung Studies

Autor: Rupert Jones, Andy Nicholls, Dominy Browning, Nawar Diar Bakerly, Ashley Woodcock, Jørgen Vestbo, David A. Leather, Loretta Jacques, James Lay-Flurrie, Henrik Svedsater, Susan Collier

Publikováno v: ERJ Open Research, Vol 6, Iss 1 (2020)

COPD and asthma prevalence is associated with socioeconomic status (or “deprivation”), yet deprivation is rarely considered in typical large-scale efficacy randomised controlled trials that recruit highly selected patient populations. In this pos

Externí odkaz: https://doaj.org/article/1c382ce7ae1747c9b2928ab1ce04f659

Benefit and safety of fluticasone furoate/vilanterol in the Salford Lung Study in chronic obstructive pulmonary disease (SLS COPD) according to baseline patient characteristics and treatment subgroups

Autor: Susan Collier, Nawar Diar Bakerly, Jørgen Vestbo, John P. New, Ashley Woodcock, Jodie Crawford, Catherine Harvey, David Leather, Isabelle Boucot

Publikováno v: Bakerly, N D, Woodcock, A, Collier, S, Leather, D A, New, J P, Crawford, J, Harvey, C, Vestbo, J & Boucot, I 2019, ' Benefit and safety of fluticasone furoate/vilanterol in the Salford Lung Study in chronic obstructive pulmonary disease (SLS COPD) according to baseline patient characteristics and treatment subgroups ', Respiratory Medicine, vol. 147, pp. 58-65 . https://doi.org/10.1016/j.rmed.2018.12.016

Background: SLS COPD was the first open-label randomised controlled trial demonstrating a reduction in moderate/severe COPD exacerbations with once-daily inhaled fluticasone furoate/vilanterol (FF/VI) in everyday clinical practice. Here we report FF/

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8499e2ec66cf05b50aeb568c85c2ad9c
https://doi.org/10.1016/j.rmed.2018.12.016

Patient and healthcare professional experiences of the Salford Lung Studies: qualitative insights for future effectiveness trials

Autor: David Leather, Lynda C. Doward, Sheila McCorkindale, Elaine A. Irving, Rebecca Conroy, Kim Gemzoe, Rebecca Crawford, Susan Collier, Renu M. Vekaria, Ann Louise Caress, Sally Worsley

Publikováno v: Trials
Trials, Vol 21, Iss 1, Pp 1-12 (2020)

Background Randomized controlled trials (RCTs) conducted in the routine care setting provide the opportunity to better understand the effectiveness of new medicines but can present recruitment difficulties. An improved understanding of the challenges

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d34b248385ad2871b1bd8d0defca251
https://pubmed.ncbi.nlm.nih.gov/32943093

Hospital‐acquired pressure injuries

Autor: Candice Irvin, Christine Walton, Elizabeth Sedlak, Susan Collier, Esther I. Bernhofer

Publikováno v: Journal of the American Association of Nurse Practitioners. 29:203-208

Background and purpose Hospital-acquired pressure injuries (HAPIs) continue to be a persistent problem in the acute care arena. The purpose of this retrospective quality improvement study was to examine if the introduction of nurse practitioners (NPs

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da85497217caee1fd6cdb4db8b36f762
https://doi.org/10.1002/2327-6924.12440