Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Suryaprakash Raichur"'
Autor:
Suryaprakash Raichur, Bodo Brunner, Maximilian Bielohuby, Gitte Hansen, Anja Pfenninger, Bing Wang, Jens C. Bruning, Philip Just Larsen, Norbert Tennagels
Publikováno v:
Molecular Metabolism, Vol 21, Iss , Pp 36-50 (2019)
Objective: Ectopic fat deposition is associated with increased tissue production of ceramides. Recent genetic mouse studies suggest that specific sphingolipid C16:0 ceramide produced by ceramide synthase 6 (CerS6) plays an important role in the devel
Externí odkaz:
https://doaj.org/article/ed86172c67e2412399a12318a5414e66
Autor:
Nicole Ziegler, Suryaprakash Raichur, Bodo Brunner, Ulrike Hemmann, Manuela Stolte, Uwe Schwahn, Hans-Peter Prochnow, Christiane Metz-Weidmann, Norbert Tennagels, Daniel Margerie, Paulus Wohlfart, Maximilian Bielohuby
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2020)
Histone deacetylases (HDACs) are important regulators of epigenetic gene modification that are involved in the transcriptional control of metabolism. In particular class IIa HDACs have been shown to affect hepatic gluconeogenesis and previous approac
Externí odkaz:
https://doaj.org/article/74f32a6ec3d54b29892a56ffad88cff3
Autor:
Suryaprakash Raichur
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2020)
Ceramide synthases (CerS) are central enzymes required for the de-novo synthesis of ceramides and other sphingolipids. They catalyze the addition of different acyl-chains to a sphingoid base, and thus account for much of the rich diversity in the sph
Externí odkaz:
https://doaj.org/article/bb73d4423eef4e98ab8068b915681a81
Autor:
Maximilian Bielohuby, Bodo Brunner, Jens C. Brüning, Anja Pfenninger, Norbert Tennagels, Philip Just Larsen, Gitte Hansen, Bing Wang, Suryaprakash Raichur
Publikováno v:
Molecular Metabolism, Vol 21, Iss, Pp 36-50 (2019)
Molecular Metabolism
Molecular Metabolism
Objective Ectopic fat deposition is associated with increased tissue production of ceramides. Recent genetic mouse studies suggest that specific sphingolipid C16:0 ceramide produced by ceramide synthase 6 (CerS6) plays an important role in the develo
Autor:
Maximilian Bielohuby, Ulrike Hemmann, Christiane Metz-Weidmann, Manuela Stolte, Daniel Margerie, Suryaprakash Raichur, Norbert Tennagels, Uwe Schwahn, Paulus Wohlfart, Nicole Ziegler, Hans-Peter Prochnow, Bodo Brunner
Publikováno v:
Frontiers in Endocrinology
Frontiers in Endocrinology, Vol 11 (2020)
Frontiers in Endocrinology, Vol 11 (2020)
Histone deacetylases (HDACs) are important regulators of epigenetic gene modification that are involved in the transcriptional control of metabolism. In particular class IIa HDACs have been shown to affect hepatic gluconeogenesis and previous approac
Autor:
Sharma, Sudhir, Sowjanya, Angaru, Kumari, Manju, Suryaprakash, Raichur, Cynthia, Gershome, Suresh, Juluri, Chakrabarti, Ranjan
Publikováno v:
In Life Sciences 2006 80(3):235-244
Autor:
Suryaprakash Raichur, Jean-Paul Kovalik, Wee Siong Chew, Ing Wei Khor, Jianhong Ching, Federico Torta, Deron R. Herr, Xueling Sim, E. Shyong Tai, Jin-Fang Chai, Chin Meng Khoo, Markus R. Wenk
Publikováno v:
Human molecular genetics. 29(2)
Metabolites are small intermediate products of cellular metabolism perturbed in a variety of complex disorders. Identifying genetic markers associated with metabolite concentrations could delineate disease-related metabolic pathways in humans. We tes
Autor:
Norbert Tennagels, Kerstin Jahn-Hofmann, Manuela Stolte, Bodo Brunner, Maximilian Bielohuby, Paulus Wohlfart, Ulrike Hemmann, Sven W. Görgens, Suryaprakash Raichur
Publikováno v:
Endocrine Abstracts.
Autor:
Ozan Kahramanoğulları, Melissa J. Morine, Corrado Priami, Hans-Christoph Schneider, Federico Reali, Suryaprakash Raichur, Daniel Crowther
Publikováno v:
Scientific Reports
Recent research adds to a growing body of literature on the essential role of ceramides in glucose homeostasis and insulin signaling, while the mechanistic interplay between various components of ceramide metabolism remains to be quantified. We prese
Autor:
Suryaprakash, Raichur, Siew Tein, Wang, Puck Wee, Chan, Ying, Li, Jianhong, Ching, Bhagirath, Chaurasia, Bghagirath, Chaurasia, Shaillay, Dogra, Miina K, Öhman, Kosuke, Takeda, Shigeki, Sugii, Yael, Pewzner-Jung, Anthony H, Futerman, Scott A, Summers
Publikováno v:
Cell Metabolism. 20(4):687-695
Summary Inhibition of ceramide synthesis prevents diabetes, steatosis, and cardiovascular disease in rodents. Six different ceramide synthases (CerS) that differ in tissue distribution and substrate specificity account for the diversity in acyl-chain