Zobrazeno 1 - 10
of 125
pro vyhledávání: '"Suryanarayanarao Ramakumar"'
Autor:
Prakruti R. Singh, Venkatareddy Dadireddy, Shubha Udupa, Shashwath Malli Kalladi, Somnath Shee, Sanjeev Khosla, Raju S. Rajmani, Amit Singh, Suryanarayanarao Ramakumar, Valakunja Nagaraja
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Mycobacterium tuberculosis has evolved several mechanisms to counter host defense arsenals for its proliferation. Here we report that M. tuberculosis employs a multi-pronged approach to modify host epigenetic machinery for its survival. It s
Externí odkaz:
https://doaj.org/article/a35a85850b474c0099f01869a8023291
Autor:
Amit Bhardwaj, Pranjal Mahanta, Suryanarayanarao Ramakumar, Amit Ghosh, Sadhu Leelavathi, Vanga Siva Reddy
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 2, Iss 3, p e201209014 (2012)
Xylanases belong to an important class of industrial enzymes. Various xylanases have been purified and characterized from a plethora of organisms including bacteria, marine algae, plants, protozoans, insects, snails and crustaceans. Depending on the
Externí odkaz:
https://doaj.org/article/209c56cec4854faeba001d13d6e8b259
Autor:
Amit Bhardwaj, Sadhu Leelavathi, Sudeshna Mazumdar-Leighton, Amit Ghosh, Suryanarayanarao Ramakumar, Vanga S Reddy
Publikováno v:
PLoS ONE, Vol 5, Iss 6, p e11347 (2010)
BACKGROUND: Stabilization strategies adopted by proteins under extreme conditions are very complex and involve various kinds of interactions. Recent studies have shown that a large proportion of proteins have their N- and C-terminal elements in close
Externí odkaz:
https://doaj.org/article/dd1ee02b92c542b2a4a1b659a16ea6d2
Autor:
Amit Bhardwaj, Sadhu Leelavathi, Sudeshna Mazumdar-Leighton, Amit Ghosh, Suryanarayanarao Ramakumar, Vanga S. Reddy
Publikováno v:
PLoS ONE, Vol 4, Iss 2 (2009)
Externí odkaz:
https://doaj.org/article/123b95decd5b4866ab8853740c9545c3
Autor:
Amit Bhardwaj, Sadhu Leelavathi, Sudeshna Mazumdar-Leighton, Amit Ghosh, Suryanarayanarao Ramakumar, Vanga S Reddy
Publikováno v:
PLoS ONE, Vol 3, Iss 8, p e3063 (2008)
BACKGROUND: Understanding the mechanisms that govern protein stability under poly-extreme conditions continues to be a major challenge. Xylanase (BSX) from Bacillus sp. NG-27, which has a TIM-barrel structure, shows optimum activity at high temperatu
Externí odkaz:
https://doaj.org/article/0cf129e0cd7c45feb0903b7f1a45dab1
Autor:
Prakruti R Singh, Venkatareddy Dadireddy, Shubha Udupa, Shashwath Malli Kalladi, Somnath Shee, Sanjeev Khosla, Raju S Rajmani, Amit Singh, Suryanarayanarao Ramakumar, Valakunja Nagaraja
Mycobacterium tuberculosis(Mtb) has evolved several mechanisms to counter host defense arsenal for its proliferation. We show thatMtbemploys multi-pronged approach to modify host epigenetic machinery for its survival upon infection. It secretes methy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::375c46380fb581e2af3c524f22aa1035
https://doi.org/10.1101/2023.02.24.529973
https://doi.org/10.1101/2023.02.24.529973
Publikováno v:
Methods in Molecular Biology ISBN: 9781071629734
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25624a5138b991f20d65c08ed40c6cd9
https://doi.org/10.1007/978-1-0716-2974-1_16
https://doi.org/10.1007/978-1-0716-2974-1_16
Publikováno v:
Journal of Chemical Information and Modeling. 61:4442-4454
The emergence of new viral infections and drug resistant bacteria urgently necessitates expedient therapeutic development. Repurposing and redesign of existing drugs against different targets is one potential way in which to accelerate this process.
Publikováno v:
Journal of chemical information and modeling. 61(3)
Cryptic pockets are visible in ligand-bound protein structures but are occluded in unbound structures. Utilizing these pockets in fragment-based drug-design provides an attractive option for proteins not tractable by classical binding sites. However,
Autor:
Rajendra P. Roy, Tora Biswas, Sreetama Das, Prity Yadav, Suryanarayanarao Ramakumar, Anurag Misra
Publikováno v:
The Biochemical journal.
The anchoring of the surface proteins to the cell wall in gram-positive bacteria involves a peptide ligation reaction catalyzed by transpeptidase sortase. Most bacterial genomes encode multiple sortases with dedicated functions. Streptococcus pneumon