Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Suryanarayana Raju Gottumukkala"'
Autor:
Shaik Mohammad Naushad, Vijay Kumar Kutala, Suryanarayana Raju Gottumukkala, Raghunadha Rao Digumarti, Yedluri Rupasree, Shree Divyya, Addepalli Pavani
Publikováno v:
Journal of Medical and Allied Sciences, Vol 1, Iss 1, Pp 7-13 (2011)
This study addresses the issues in translating the laboratory derived data obtained during discovery phase of research to a clinical setting using a breast cancer model. Laboratory-based risk assessment indi-cated that a family history of breast canc
Externí odkaz:
https://doaj.org/article/e159b41919ea4143a1d643b57a293132
Autor:
Shree Divyya, Shaik Mohammad Naushad, Suryanarayana Raju Gottumukkala, P.V.L.N. Murthy, Raghunadharao Digumarti, S. Rammurti, Ajit Kumar, Ch. Ram Reddy, Vijay Kumar Kutala, Anthony Addlagatta
Publikováno v:
Gene. 497:273-279
Glutamate carboxypeptidase II (GCPII) is predominantly expressed in brain, intestinal mucosa and prostate cancer in the form of three splice variants i.e. N-acetylated-α-linked acidic dipeptidase (NAALADase), folyl poly-γ-glutamate carboxypeptidase
Autor:
Salman A. H. Alrokayan, M. Janaki Ramaiah, Shaik Mohammad Naushad, Raghunadharao Digumarti, Manickam Pavithrakumari, Vijay Kumar Kutala, Tajamul Hussain, Jaganathan Jayapriya, Suryanarayana Raju Gottumukkala
Publikováno v:
Gene. 580(2)
In the current study, an artificial neural network (ANN)-based breast cancer prediction model was developed from the data of folate and xenobiotic pathway genetic polymorphisms along with the nutritional and demographic variables to investigate how m
Autor:
Yedluri Rupasree, Shaik Mohammad Naushad, Raghunadharao Digumarti, Aruna K Prayaga, Addepalli Pavani, Suryanarayana Raju Gottumukkala, Shree Divyya, Sripurna Deepti, Vijay Kumar Kutala
Publikováno v:
Molecular Carcinogenesis. 51:E32-E41
We have earlier demonstrated the role of aberrant one-carbon metabolism in the etiology of breast cancer. In the current study, we examine the clinical utility of these factors in predicting the subtype of breast cancer and as indicators of disease p
Autor:
Vijay Kumar Kutala, Shaik Mohammad Naushad, Aruna K Prayaga, Raghunadharao Digumarti, Suryanarayana Raju Gottumukkala
Publikováno v:
Molecular and Cellular Biochemistry. 361:189-195
In view of recent studies highlighting the prognostic relevance of expression and CpG island methylator phenotype (CIMP) of Bcl-2/adenovirus E1B 19 kDa-interacting protein 3 (BNIP3) in invasive duct cell carcinoma (IDC), we hypothesized in this artic
Autor:
Shaik Mohammad Naushad, Periannan Kuppusamy, Cheruku Apoorva Reddy, Raghunadharao Digumarti, Addepalli Pavani, Yedluri Rupasree, Vijay Kumar Kutala, Suryanarayana Raju Gottumukkala
Publikováno v:
Cell Biochemistry and Biophysics. 61:715-723
The aim of this case-control study is to explore the role of aberrations in xenobiotic metabolism in inducing oxidative DNA damage and altering the susceptibility to breast cancer. Cytochrome P4501A1 (CYP1A1) m1 (OR: 1.41, 95% CI 1.08-1.84), CYP1A1 m
Autor:
Rupasree Yedluri, Vijay Kumar Kutala, Naushad Shaik Mohammad, Suryanarayana Raju Gottumukkala, Raghunadharao Digumarti, Pavani Addepalli
Publikováno v:
Molecular and Cellular Biochemistry. 349:159-167
The authors investigated the role of dietary micronutrients and eight functional polymorphisms of one-carbon metabolism in modulating oxidative stress in sporadic breast cancer. PCR-restriction fragment length polymorphism (RFLP) and PCR-amplified fr
Autor:
Cheruku Apoorva Reddy, Vijay Kumar Kutala, Konda Kumaraswami, Raghunadharao Digumarti, Shaik Mohammad Naushad, Srigiridhar Kotamraju, Shree Divyya, Suryanarayana Raju Gottumukkala
Publikováno v:
Cell biochemistry and biophysics. 68(2)
Our recent study showing association of hyperhomocysteinemia and hypomethioninemia in breast cancer and other studies indicating association of hyperhomocysteinemia with metastasis and development of drug resistance in breast cancer cells treated wit
Association of glutamate carboxypeptidase II (GCPII) haplotypes with breast and prostate cancer risk
Autor:
Ch. Ram Reddy, Anthony Addlagatta, Shaik Mohammad Naushad, Shree Divyya, Raghunadharao Digumarti, Sreedhar Amere Subbarao, Vijay Kumar Kutala, Suryanarayana Raju Gottumukkala, P.V.L.N. Murthy
Publikováno v:
Gene. 516(1)
In view of the pivotal role of glutamate carboxypeptidase II (GCPII) in carcinogenesis, its expression as prostate specific membrane antigen (PSMA) and folate hydrolase (FOLH1) may be influenced by its haplotypes, contributing to the etiology of pros
Autor:
Shaik Mohammad, Naushad, Addepalli, Pavani, Yedluri, Rupasree, Deepti, Sripurna, Suryanarayana Raju, Gottumukkala, Raghunadha Rao, Digumarti, Vijay Kumar, Kutala
Publikováno v:
Indian journal of biochemistrybiophysics. 48(4)
The present study was aimed to investigate the modulatory role of plasma folate and eight putatively functional polymorphisms of one-carbon metabolism on catecholamine methyltransferase (COMT)-mediated oxidative DNA damage and breast cancer risk. Pla