Zobrazeno 1 - 10
of 163
pro vyhledávání: '"Surya M Nauli"'
Autor:
Daniel T Grimes, Jennifer L Keynton, Maria T Buenavista, Xingjian Jin, Saloni H Patel, Shinohara Kyosuke, Jennifer Vibert, Debbie J Williams, Hiroshi Hamada, Rohanah Hussain, Surya M Nauli, Dominic P Norris
Publikováno v:
PLoS Genetics, Vol 12, Iss 6, p e1006070 (2016)
During mammalian development, left-right (L-R) asymmetry is established by a cilia-driven leftward fluid flow within a midline embryonic cavity called the node. This 'nodal flow' is detected by peripherally-located crown cells that each assemble a pr
Externí odkaz:
https://doaj.org/article/846e1cdd51ad455a997231888bc7b258
Autor:
Nicholas Doerr, Yidi Wang, Kevin R Kipp, Guangyi Liu, Jesse J Benza, Vladimir Pletnev, Tengis S Pavlov, Alexander Staruschenko, Ashraf M Mohieldin, Maki Takahashi, Surya M Nauli, Thomas Weimbs
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0161525 (2016)
Autosomal Dominant Polycystic Kidney Disease (ADPKD) is a common genetic disease that leads to progressive renal cyst growth and loss of renal function, and is caused by mutations in the genes encoding polycystin-1 (PC1) and polycystin-2 (PC2), respe
Externí odkaz:
https://doaj.org/article/2dd1bd64898141e3a8683112f025fee9
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e100967 (2014)
A Disintegrin And Metalloproteinase with ThromboSpondin motifs16 (ADAMTS-16) is a member of a family of metalloproteinases. Using a novel zinc-finger nuclease based gene-edited rat model harboring a targeted mutation of the Adamts16 locus, we previou
Externí odkaz:
https://doaj.org/article/589fa6502d8245bd94d34d026ef34ddc
Autor:
Ashwaq Alanazi, Ayan K. Barui, Ashraf M. Mohieldin, Ankan Gupta, Ramani Ramchandran, Surya M. Nauli
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Emerging evidence suggests a significant contribution of primary cilia to cell division and proliferation. MicroRNAs, especially miR-17, contribute to cell cycle regulation and proliferation. Recent investigations have highlighted the dysregulated ex
Externí odkaz:
https://doaj.org/article/f9437e5212934e71be27b830481f85ed
Autor:
Yoshifumi Kawanabe, Maki Takahashi, Xingjian Jin, Shakila Abdul-Majeed, Andromeda M Nauli, Youssef Sari, Surya M Nauli
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e44476 (2012)
Cilostazol is a phosphodiesterase inhibitor that has been shown to inhibit platelet activation. Endothelin is known to be the most potent endogenous growth promoting and vasoactive peptide. In patients and animal models with stroke, the level of circ
Externí odkaz:
https://doaj.org/article/58b278e07eb84f6e8ffc9be91bfe2b69
Autor:
Muhammad Imran Sajid, Francisco J. Nunez, Farideh Amirrad, Moom Rahman Roosan, Tom Vojtko, Scott McCulloch, Amal Alachkar, Surya M. Nauli
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Chronic hypoxia may have a huge impact on the cardiovascular and renal systems. Advancements in microscopy, metabolomics, and bioinformatics provide opportunities to identify new biomarkers. In this study, we aimed at elucidating the metabol
Externí odkaz:
https://doaj.org/article/05da8bb9b7964d92ad276c1e1ef734ed
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Larger intestinal lipoproteins are more likely to be retained longer in the intestinal wall, allowing more time for their fat to be hydrolyzed and subsequently taken up by the abdominal viscera. Since men generally accumulate more abdominal visceral
Externí odkaz:
https://doaj.org/article/eba2e235c1a74b76aaca2016852aadbd
Publikováno v:
Biomolecules, Vol 14, Iss 3, p 334 (2024)
The human gastrointestinal system is a complex ecosystem crucial for well-being. During sepsis-induced gut injury, the integrity of the intestinal barrier can be compromised. Lipopolysaccharide (LPS), an endotoxin from Gram-negative bacteria, disrupt
Externí odkaz:
https://doaj.org/article/844f655ab4b8446987bb7fecded317d7
Autor:
Karthikeyan Thirugnanam, Ankan Gupta, Francisco Nunez, Shubhangi Prabhudesai, Amy Y. Pan, Surya M. Nauli, Ramani Ramchandran
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Primary cilia from the brain microvascular endothelial cells (ECs) are specialized cell-surface organelles involved in mediating sensory perception, cell signaling, and vascular stability. Immunofluorescence (IF) analysis of human primary brain micro
Externí odkaz:
https://doaj.org/article/1c0ac12c84234ae89bd5b4e9f5f3497d
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract During drug development, evaluation of drug and its metabolite is an essential process to understand drug activity, stability, toxicity and distribution. Liquid chromatography (LC) coupled with mass spectrometry (MS) has become the standard
Externí odkaz:
https://doaj.org/article/ec764b8aa77f4b9cbaba4ef2af6774b5