Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Surya D. Aggarwal"'
Autor:
Anne-Stéphanie Rueff, Renske van Raaphorst, Surya D. Aggarwal, Javier Santos-Moreno, Géraldine Laloux, Yolanda Schaerli, Jeffrey N. Weiser, Jan-Willem Veening
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Phenotypic variation is the phenomenon in which clonal cells display different traits even under identical environmental conditions. This plasticity is thought to be important for processes including bacterial virulence, but direct evidence
Externí odkaz:
https://doaj.org/article/e8c7dfd4d89b4c2a9b32de5868db46ec
Publikováno v:
mBio, Vol 13, Iss 2 (2022)
ABSTRACT Capsule-switch mutants were compared to analyze how serotype affects the success of Streptococcus pneumoniae (Spn) during colonization and transmission. Strains of multiple serotypes were tested in highly susceptible infant mice, both singly
Externí odkaz:
https://doaj.org/article/d1460143100e4effb63ed74dd203024d
Autor:
Saigopalakrishna S. Yerneni, Sarah Werner, Juliana H. Azambuja, Nils Ludwig, Rory Eutsey, Surya D. Aggarwal, Peter C. Lucas, Nathanael Bailey, Theresa L. Whiteside, Phil G. Campbell, N. Luisa Hiller
Publikováno v:
mBio, Vol 12, Iss 4 (2021)
ABSTRACT Extracellular vesicles (EVs) have recently garnered attention for their participation in host-microbe interactions in pneumococcal infections. However, the effect of EVs on the host immune system remain poorly understood. Our studies focus o
Externí odkaz:
https://doaj.org/article/daf0bbbac4384c3cb6fb8c58d8262fcc
Autor:
Surya D. Aggarwal, Jessica M. Gullett, Tara Fedder, J. Pedro F. Safi, Charles O. Rock, N. Luisa Hiller
Publikováno v:
mSphere, Vol 6, Iss 3 (2021)
Adaptation of bacteria to their host environment is a key component of colonization and pathogenesis. As an essential component of bacterial membranes, fatty acid composition contributes to host adaptation.
Externí odkaz:
https://doaj.org/article/dc72b3001b8c4992b928d5199381fe64
Autor:
Alexandria J Hammond, Ulrike Binsker, Surya D Aggarwal, Mila Brum Ortigoza, Cynthia Loomis, Jeffrey N Weiser
Publikováno v:
PLoS Pathogens, Vol 17, Iss 4, p e1009158 (2021)
Binding of Streptococcus pneumoniae (Spn) to nasal mucus leads to entrapment and clearance via mucociliary activity during colonization. To identify Spn factors allowing for evasion of mucus binding, we used a solid-phase adherence assay with immobil
Externí odkaz:
https://doaj.org/article/d230cce3a6e3483ea2fe0a28d2481612
Autor:
Surya D. Aggarwal, John A. Lees, Nathan T. Jacobs, Gavyn Chern Wei Bee, Annie R. Abruzzo, Jeffrey N. Weiser
SUMMARYChromosomal barcoding and high-throughput sequencing were used to investigate the population dynamics of Streptococcus pneumoniae. During infant mouse colonization, >35-fold reduction in diversity and expansion of a single clonal lineage was o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39484fa20b4b6e5dd10c36bf1ce8e552
https://doi.org/10.1101/2022.08.05.500807
https://doi.org/10.1101/2022.08.05.500807
Autor:
J Pedro F Safi, Jessica M. Gullett, Surya D. Aggarwal, Charles O. Rock, N. Luisa Hiller, Tara Fedder
Publikováno v:
mSphere
mSphere, Vol 6, Iss 3 (2021)
mSphere, Vol 6, Iss 3 (2021)
Membrane lipid homeostasis is required for bacteria to survive in a spectrum of host environments. This homeostasis is achieved by regulation of fatty acid chain length and of the ratio of unsaturated to saturated fatty acids. In the pathogen Strepto
Autor:
Surya D, Aggarwal, Adrian J, Lloyd, Saigopalakrishna S, Yerneni, Ana Rita, Narciso, Jennifer, Shepherd, David I, Roper, Christopher G, Dowson, Sergio R, Filipe, N Luisa, Hiller
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance During infection, microbes must survive the hostile environmental conditions of the human host. When exposed to stresses, bacteria activate an intracellular response, known as the stringent response pathway, to ensure their survival. Thi
Autor:
T. Fedder, Jessica M. Gullett, Charles O. Rock, Surya D. Aggarwal, J. P. F. Safi, N. L. Hiller
Membrane lipid homeostasis is required for bacteria to survive in a spectrum of host environments. This homeostasis is achieved by regulation of fatty acid chain length and of the ratio of saturated to unsaturated fatty acids. In the pathogen Strepto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32f4eccca7ad8480365b847c8e6a0378
https://doi.org/10.1101/2021.02.17.431746
https://doi.org/10.1101/2021.02.17.431746
Publikováno v:
SSRN Electronic Journal.
International scientists, engineers, and students have made and continue to make significant contributions to the U.S.’s science and engineering research enterprise. This source of talent is a comparative advantage for the U.S. and is critical for