Zobrazeno 1 - 10
of 169
pro vyhledávání: '"Surulescu, Christina"'
Autor:
Eckardt, Maria, Surulescu, Christina
We consider a model for the dynamics of active cells interacting with their quiescent counterparts under the influence of acidity characterized by proton concentration. The active cells perform nonlinear diffusion and infer proliferation or decay, ac
Externí odkaz:
http://arxiv.org/abs/2409.12657
Autor:
Jäger, Henry, Grosjean, Élise, Plunder, Steffen, Redenbach, Claudia, Keilmann, Alex, Simeon, Bernd, Surulescu, Christina
We study the dynamics of a seeding experiment where a fibrous scaffold material is colonized by two types of cell populations. The specific application that we have in mind is related to the idea of meniscus tissue regeneration. In order to support t
Externí odkaz:
http://arxiv.org/abs/2406.06334
Autor:
Grosjean, Elise, Keilmann, Alex, Jäger, Henry, Mohanan, Shimi, Redenbach, Claudia, Simeon, Bernd, Surulescu, Christina, de Roy, Luisa, Seitz, Andreas, Teixeira, Graciosa, Dauner, Martin, Linti, Carsten, Schmidt, Günter
We develop a model the dynamics of human mesenchymal stem cells (hMSCs) and chondrocytes evolving in a nonwoven polyethylene terephtalate (PET) scaffold impregnated with hyaluron and supplied with a differentiation medium. The scaffold and the cells
Externí odkaz:
http://arxiv.org/abs/2403.05909
We propose a PDE-ODE model for tissue regeneration, obtained by parabolic upscaling from kinetic transport equations written for the mesoscopic densities of mesenchymal stem cells and chondrocytes which evolve in an artificial scaffold impregnated wi
Externí odkaz:
http://arxiv.org/abs/2403.04516
We propose a continuous model for meniscus cartilage regeneration triggered by two populations of cells migrating and (de)differentiating within an artificial scaffold with a known structure. The described biological processes are influenced by a flu
Externí odkaz:
http://arxiv.org/abs/2308.11255
Autor:
Eckardt, Maria, Surulescu, Christina
Starting from a mesoscopic description of cell migration and intraspecific interactions we obtain by upscaling an effective reaction-difusion-taxis equation for the cell population density involving spatial nonlocalities in the source term and biasin
Externí odkaz:
http://arxiv.org/abs/2307.15342
In this paper we propose a data-driven methodology to gain insight into the formation of different types of pseudopalisade structures. To this end, we start from a state of the art macroscopic model for the dynamics of GBM, that is coupled with the d
Externí odkaz:
http://arxiv.org/abs/2208.08536
A multiscale model for glioma spread in brain tissue under the influence of vascularization and vascular endothelial growth factors is proposed. It accounts for the interplay between the different components of the neoplasm and the healthy tissue and
Externí odkaz:
http://arxiv.org/abs/2203.11578
We propose a multiphase modeling approach to describe glioma pseudopalisade patterning under the influence of acidosis. The phases considered at the model onset are glioma, normal tissue, necrotic matter, and interstitial fluid in a void-free volume
Externí odkaz:
http://arxiv.org/abs/2106.15241
Autor:
Zhigun, Anna, Surulescu, Christina
In this work we upscale a prototypical kinetic transport equation which models a cell population moving in a fibrous environment with a chemo- or haptotactic signal influencing both the direction and the magnitude of the cell velocity. The presented
Externí odkaz:
http://arxiv.org/abs/2010.04148