Role of the Fourth Transmembrane α Helix in the Allosteric Modulation of Pentameric Ligand-Gated Ion Channels.

Autor: Carswell CL; Department of Biochemistry, Microbiology, and Immunology, 451 Smyth Road, Ottawa, ON K1H 8M5, Canada., Hénault CM; Department of Biochemistry, Microbiology, and Immunology, 451 Smyth Road, Ottawa, ON K1H 8M5, Canada., Murlidaran S; Center for Computational and Integrative Biology, Rutgers University-Camden, Camden, NJ 08102, USA., Therien JPD; Department of Biochemistry, Microbiology, and Immunology, 451 Smyth Road, Ottawa, ON K1H 8M5, Canada., Juranka PF; Department of Biochemistry, Microbiology, and Immunology, 451 Smyth Road, Ottawa, ON K1H 8M5, Canada., Surujballi JA; Department of Biochemistry, Microbiology, and Immunology, 451 Smyth Road, Ottawa, ON K1H 8M5, Canada., Brannigan G; Center for Computational and Integrative Biology, Rutgers University-Camden, Camden, NJ 08102, USA; Department of Physics, Rutgers University-Camden, Camden, NJ 08103, USA., Baenziger JE; Department of Biochemistry, Microbiology, and Immunology, 451 Smyth Road, Ottawa, ON K1H 8M5, Canada. Electronic address: john.baenziger@uottawa.ca.

Publikováno v: Structure (London, England : 1993) [Structure] 2015 Sep 01; Vol. 23 (9), pp. 1655-1664. Date of Electronic Publication: 2015 Jul 30.