Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Suruchi Arora"'
Publikováno v:
European Journal of Obstetrics & Gynecology and Reproductive Biology: X, Vol 19, Iss , Pp 100211- (2023)
The non-invasive prenatal testing (NIPT) analyses cell-free DNA (cfDNA) derived from the placental tissue in the maternal circulation. Though highly sensitive and specific, a major limitation is in cases of confined placental mosaicism (CPM). Whether
Externí odkaz:
https://doaj.org/article/47e7437829cc4738af5bd1c30c67181e
Autor:
Jianzhou Cui, Dhakshayini Morgan, Dao Han Cheng, Sok Lin Foo, Gracemary L. R. Yap, Patrick B. Ampomah, Suruchi Arora, Karishma Sachaphibulkij, Balamurugan Periaswamy, Anna-Marie Fairhurst, Paola Florez De Sessions, Lina H. K. Lim
Publikováno v:
Cells, Vol 9, Iss 6, p 1399 (2020)
Influenza viruses have been shown to use autophagy for their survival. However, the proteins and mechanisms involved in the autophagic process triggered by the influenza virus are unclear. Annexin-A1 (ANXA1) is an immunomodulatory protein involved in
Externí odkaz:
https://doaj.org/article/1aed9b14b01549c7b548e4130e3def15
Autor:
Durkeshwari Anbalagan, Gracemary Yap, Yi Yuan, Vijay K Pandey, Wai Hoe Lau, Suruchi Arora, Pradeep Bist, Justin S B Wong, Gautam Sethi, Peter M Nissom, Peter E Lobie, Lina H K Lim
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e114507 (2014)
Annexin 1 (ANXA1) is an endogenous anti-inflammatory protein implicated in cancer. ANXA1 was previously shown to be regulated by hsa-miR-196a. However, whether ANXA1 itself regulates microRNA (miR) expression is unknown. Therefore, we investigated th
Externí odkaz:
https://doaj.org/article/2f89799617844ff8908a97c16e8f0bc9
Autor:
Alan P. Kumar, Lina H.K. Lim, Gautam Sethi, Peter E. Lobie, Louis Gaboury, Joo I. Park, Boon C. Goh, Henry Yang, Han M. Shen, Frank Arfuso, Sung W. Shin, Tuan Z. Tan, Muthu K. Shanmugam, Ramar P. Samy, Einas Yousef, Pei F. Koh, Ji E. Kim, Suruchi Arora, Madhu M. Kanchi, Shreya Kar, Yi Yuan, Luxi Chen
Metastatic breast cancer is still incurable so far; new specifically targeted and more effective therapies for triple-negative breast cancer (TNBC) are required in the clinic. In this study, our clinical data have established that basal and claudin-l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19a0c0e006c3abbabd69d14315bda93e
https://doi.org/10.1158/1535-7163.c.6539263.v1
https://doi.org/10.1158/1535-7163.c.6539263.v1
Autor:
Alan P. Kumar, Lina H.K. Lim, Gautam Sethi, Peter E. Lobie, Louis Gaboury, Joo I. Park, Boon C. Goh, Henry Yang, Han M. Shen, Frank Arfuso, Sung W. Shin, Tuan Z. Tan, Muthu K. Shanmugam, Ramar P. Samy, Einas Yousef, Pei F. Koh, Ji E. Kim, Suruchi Arora, Madhu M. Kanchi, Shreya Kar, Yi Yuan, Luxi Chen
Supplementary Figure 1: High ANXA1 and PPARγ expression levels positively correlates with the invasive, high-grade phenotype
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::796a52bb0d216b583547635ad48b7918
https://doi.org/10.1158/1535-7163.22509319
https://doi.org/10.1158/1535-7163.22509319
Autor:
Alan P. Kumar, Lina H.K. Lim, Gautam Sethi, Peter E. Lobie, Louis Gaboury, Joo I. Park, Boon C. Goh, Henry Yang, Han M. Shen, Frank Arfuso, Sung W. Shin, Tuan Z. Tan, Muthu K. Shanmugam, Ramar P. Samy, Einas Yousef, Pei F. Koh, Ji E. Kim, Suruchi Arora, Madhu M. Kanchi, Shreya Kar, Yi Yuan, Luxi Chen
Supplementary Figure 2: ANXA1 expressing TNBC cell lines display greater sensitivity to PPARγ ligands compared to ANXA1 depleted cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48392110051076c68f80b12a3c9855ed
https://doi.org/10.1158/1535-7163.22509316
https://doi.org/10.1158/1535-7163.22509316
Autor:
Alan P. Kumar, Lina H.K. Lim, Gautam Sethi, Peter E. Lobie, Louis Gaboury, Joo I. Park, Boon C. Goh, Henry Yang, Han M. Shen, Frank Arfuso, Sung W. Shin, Tuan Z. Tan, Muthu K. Shanmugam, Ramar P. Samy, Einas Yousef, Pei F. Koh, Ji E. Kim, Suruchi Arora, Madhu M. Kanchi, Shreya Kar, Yi Yuan, Luxi Chen
Supplementary methods and supplementary figure legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69a6963a538aeeeffe32e7e217be5f31
https://doi.org/10.1158/1535-7163.22509322.v1
https://doi.org/10.1158/1535-7163.22509322.v1
Autor:
Alan P. Kumar, Lina H.K. Lim, Gautam Sethi, Peter E. Lobie, Louis Gaboury, Joo I. Park, Boon C. Goh, Henry Yang, Han M. Shen, Frank Arfuso, Sung W. Shin, Tuan Z. Tan, Muthu K. Shanmugam, Ramar P. Samy, Einas Yousef, Pei F. Koh, Ji E. Kim, Suruchi Arora, Madhu M. Kanchi, Shreya Kar, Yi Yuan, Luxi Chen
Supplementary Figure 3: PPARγ induced expression of ANXA1 and cell death is abrogated in TNBC cells with pre-incubation of a PPARγ-specific antagonist or use of a dominant negative derivative of PPARγ.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a0f8a276b53f71a91851a1a8a4f6ab9
https://doi.org/10.1158/1535-7163.22509313.v1
https://doi.org/10.1158/1535-7163.22509313.v1
Autor:
Alan P. Kumar, Lina H.K. Lim, Gautam Sethi, Peter E. Lobie, Louis Gaboury, Joo I. Park, Boon C. Goh, Henry Yang, Han M. Shen, Frank Arfuso, Sung W. Shin, Tuan Z. Tan, Muthu K. Shanmugam, Ramar P. Samy, Einas Yousef, Pei F. Koh, Ji E. Kim, Suruchi Arora, Madhu M. Kanchi, Shreya Kar, Yi Yuan, Luxi Chen
Supplementary Figure 4: PPARγ ligand-induced changes in expression of RIP1 and NEMO and therefore NFκB activity are receptor dependent.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::970d9325507dd54cc45444196a0bdeaf
https://doi.org/10.1158/1535-7163.22509310
https://doi.org/10.1158/1535-7163.22509310
Autor:
Patrick B. Ampomah, Suruchi Arora, Dao Han Cheng, Gracemary Yap, Karishma Sachaphibulkij, Lina H. K. Lim, Balamurugan Periaswamy, Dhakshayini Morgan, Paola Florez de Sessions, Anna-Marie Fairhurst, Sok Lin Foo, Jianzhou Cui
Publikováno v:
Cells, Vol 9, Iss 1399, p 1399 (2020)
Cells
Volume 9
Issue 6
Cells
Volume 9
Issue 6
Influenza viruses have been shown to use autophagy for their survival. However, the proteins and mechanisms involved in the autophagic process triggered by the influenza virus are unclear. Annexin-A1 (ANXA1) is an immunomodulatory protein involved in