Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Suresh Savarirayan"'
Autor:
Julie Hanson, Christopher J. Krco, Chella S. David, Suresh Savarirayan, Jeanine M. Baisch, Michelle Smart, Shen Cheng, K. Hodgson
Publikováno v:
European Journal of Immunogenetics. 23:15-20
Transgenic mice expressing HLA-DQA1*0301 and HLA-DQB1*0302 genes (DQ8) were produced. The transgenes were then transferred into mouse (Ab degrees) class II negative mice: the only class II molecules expressed in these animals were therefore coded by
Autor:
Hidetoshi Inoko, Michele K. Smart, Chella S. David, Suresh Savarirayan, Shen Cheng, Paul Zhou
Publikováno v:
Immunogenetics. 35:219-223
The elusive Mls gene(s) are mouse mammary tumor virus genes. The endogenous cotolerogen involved in the clonal deletion of Tcr Vβ5.1, 5.2, and 11 in H-2E+ mouse strains has been narrowed down to MTV-9. We demonstrate that similar to H-2Eα molecules
Publikováno v:
Human Immunology. 28:382-396
The majority of patients with reactive arthritis have the major histocompatibility complex class I gene HLA-B27. The development of arthritis in these patients often occurs following infection with one of several enteric bacteria, including Yersinia
Publikováno v:
European Journal of Immunogenetics. 17:151-159
Cell surface expression of class 11 major histocompatibility complex encoded (1a) molecules depends on association of the component alpha and beta chain into a stable heterodimer. Studies on cell lines transfected with MHC class II genes have reveale
Publikováno v:
Human immunology. 31(1)
Minor lymphocyte stimulating locus (Mls) gene products in association with mouse major histocompatibility complex (MHC) class II molecules are known to determine the repertoire of T-cell receptor (TCR) in mature T cells. In order to test whether huma
Autor:
Chella S. David, David J. McKean, Bing Yuan Wei, Suresh Savarirayan, J M Buerstedde, G D Anderson, Roger G. Little, Javier Martin
Publikováno v:
Transplantation. 50(4)
Cell surface expression of Ia antigens requires the assembly of alpha and beta heterodimers. We have produced a double transgenic mouse with a wild form Ak alpha gene and a mutant Ak beta (Ak beta MB) gene with d-allele substitution at positions 63 a
Publikováno v:
The Journal of Experimental Medicine
The crossover points of nine intra-I region recombinant mouse strains were determined by restriction fragment analysis. The recombinants were examined for the presence of k and p haplotype specific DNA restriction endonuclease sites. These restrictio
Publikováno v:
Immunogenetics. 7:89-93
Publikováno v:
Immunogenetics. 22:617-623
The Mep-1 gene on chromosome 17 in mice controls the activity of meprin, a kidney brush border metalloendopeptidase. Most inbred mouse strains of the k haplotype (e.g., CBA, C3H, AKR) are markedly deficient in meprin activity; these mice carry the Me
Publikováno v:
Immunogenetics. 24:68-70