Zobrazeno 1 - 10
of 188
pro vyhledávání: '"Suresh Ramakrishna"'
Autor:
Janardhan Keshav Karapurkar, Min-Seong Kim, Jencia Carminha Colaco, Bharathi Suresh, Neha Sarodaya, Dong-Ho Kim, Chang-Hwan Park, Seok-Ho Hong, Kye-Seong Kim, Suresh Ramakrishna
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-21 (2023)
Abstract Background The repressor element-1 silencing transcription factor (REST), a master transcriptional repressor, is essential for maintenance, self-renewal, and differentiation in neuroblastoma. An elevated expression of REST is associated with
Externí odkaz:
https://doaj.org/article/1844a0e3648941b68cde2820f4b14277
Autor:
Dinh-Toi Chu, Hue Vu Thi, Tiep Tien Nguyen, Thuy-Duong Vu, Yen Vy Nguyen Thi, Indra Mani, Nisarg Gohil, Gargi Bhattacharjee, Suresh Ramakrishna, Vijai Singh
Publikováno v:
OpenNano, Vol 13, Iss , Pp 100181- (2023)
Metabolic disorders result from inborn and acquired dysfunction of organs and tissues that are responsible for producing energy in the body. These diseases are now among the most prevalent maladies in the world. Treatment often requires addressing in
Externí odkaz:
https://doaj.org/article/615ff58edf9b417fbd25f9fbd62edfbb
Autor:
Roya Rasaei, Apoorvi Tyagi, Shima Rasaei, Seung-Joon Lee, Se-Ran Yang, Kye-Seong Kim, Suresh Ramakrishna, Seok-Ho Hong
Publikováno v:
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-12 (2022)
Abstract Pulmonary fibrosis (PF) is a fatal chronic disease characterized by accumulation of extracellular matrix and thickening of the alveolar wall, ultimately leading to respiratory failure. PF is thought to be initiated by the dysfunction and abe
Externí odkaz:
https://doaj.org/article/bd411bb4f5d54fcab341650269f6fb6c
Autor:
Neha Sarodaya, Apoorvi Tyagi, Hyun-Jin Kim, Ju-Seop Kang, Vijai Singh, Seok-Ho Hong, Woo Jin Kim, Kye-Seong Kim, Suresh Ramakrishna
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Phenylalanine hydroxylase (PAH) is a key enzyme in mammals that maintains the phenylalanine (Phe) concentration at an appropriate physiological level. Some genetic mutations in the PAH gene lead to destabilization of the PAH enzyme, leading
Externí odkaz:
https://doaj.org/article/b0eba0de06fb41009751f1564969ae5c
Autor:
Gargi Bhattacharjee, Nisarg Gohil, Malvika Shukla, Swati Sharma, Indra Mani, Alok Pandya, Dinh-Toi Chu, Nhat Le Bui, Yen-Vy Nguyen Thi, Khushal Khambhati, Rupesh Maurya, Suresh Ramakrishna, Vijai Singh
Publikováno v:
OpenNano, Vol 12, Iss , Pp 100150- (2023)
The platform of microfluidics offers a precise control and manipulation over fluids at a small scale and therefore has gained much attention in recent times. This topic is currently applied to automation and high-throughput analysis in several areas,
Externí odkaz:
https://doaj.org/article/f00cb04d1a1b4a92b312504fa4d0fc89
Autor:
Khushal Khambhati, Gargi Bhattacharjee, Nisarg Gohil, Gurneet K. Dhanoa, Antonia P. Sagona, Indra Mani, Nhat Le Bui, Dinh‐Toi Chu, Janardhan Keshav Karapurkar, Su Hwa Jang, Hee Yong Chung, Rupesh Maurya, Khalid J. Alzahrani, Suresh Ramakrishna, Vijai Singh
Publikováno v:
Bioengineering & Translational Medicine, Vol 8, Iss 2, Pp n/a-n/a (2023)
Abstract Antibiotic resistance ranks among the top threats to humanity. Due to the frequent use of antibiotics, society is facing a high prevalence of multidrug resistant pathogens, which have managed to evolve mechanisms that help them evade the las
Externí odkaz:
https://doaj.org/article/26578e2808e541d9bda93e00a4d03500
Autor:
Ainsley Mike Antao, Janardhan Keshav Karapurkar, Dong Ryul Lee, Kye-Seong Kim, Suresh Ramakrishna
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 18, Iss , Pp 3649-3665 (2020)
CRISPR/Cas systems are popular genome editing tools that belong to a class of programmable nucleases and have enabled tremendous progress in the field of regenerative medicine. We here outline the structural and molecular frameworks of the well-chara
Externí odkaz:
https://doaj.org/article/0afe22bef1dd4950948cb1e149243574
Publikováno v:
Redox Biology, Vol 48, Iss , Pp 102194- (2021)
Reactive oxygen species (ROS) act as a double-edged sword in cancer, where low levels of ROS are beneficial but excessive accumulation leads to cancer progression. Elevated levels of ROS in cancer are counteracted by the antioxidant defense system. A
Externí odkaz:
https://doaj.org/article/9e86097e17c44e0584804c8b9f893765
Autor:
Kamini Kaushal, Apoorvi Tyagi, Janardhan Keshav Karapurkar, Eun-Jung Kim, Parthasaradhireddy Tanguturi, Kye-Seong Kim, Han-Sung Jung, Suresh Ramakrishna
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 2, p 856 (2022)
The osteoblast differentiation capacity of mesenchymal stem cells must be tightly regulated, as inadequate bone mineralization can lead to osteoporosis, and excess bone formation can cause the heterotopic ossification of soft tissues. The balanced pr
Externí odkaz:
https://doaj.org/article/018e6a0f3156434dab958ac92f62bc2e
Autor:
Na Re Ko, Sang Ju Lee, Arun Pandian Chandrasekaran, Apoorvi Tyagi, Suresh Ramakrishna, Seog-Young Kim, Do Won Kim, Chan-Gi Pack, Seung Jun Oh
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 20, p 11298 (2021)
Chemotherapy is one of the most effective treatments for cancer. However, intracellular delivery of many anticancer drugs is hindered by their hydrophobicity and low molecular weight. Here, we describe highly biocompatible and biodegradable amphiphil
Externí odkaz:
https://doaj.org/article/f38fa36f02a34b4796d2c5022b488d63