Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Suresh N. Kumar"'
Autor:
Shelby E. Hamm, Daniel D. Fathalikhani, Katherine E. Bukovec, Adele K. Addington, Haiyan Zhang, Justin B. Perry, Ryan P. McMillan, Michael W. Lawlor, Mariah J. Prom, Mark A. Vanden Avond, Suresh N. Kumar, Kirsten E. Coleman, J.B. Dupont, David L. Mack, David A. Brown, Carl A. Morris, J. Patrick Gonzalez, Robert W. Grange
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 21, Iss , Pp 144-160 (2021)
We tested the hypothesis that voluntary wheel running would complement microdystrophin gene therapy to improve muscle function in young mdx mice, a model of Duchenne muscular dystrophy. mdx mice injected with a single dose of AAV9-CK8-microdystrophin
Externí odkaz:
https://doaj.org/article/d1cbb7f0e57f48a4854b84e1f8896a3a
Autor:
Farnaz H. Foomani, Jason A. Jarzembowski, Soudeh Mostaghimi, Shima Mehrvar, Suresh N. Kumar, Mahsa Ranji
Publikováno v:
IEEE Journal of Translational Engineering in Health and Medicine, Vol 9, Pp 1-7 (2021)
Background: Mitochondrial $\beta $ -oxidation of fatty acids is the primary energy source for the heart and carried out by Hydroxy Acyl-CoA Dehydrogenase (HADH) encoded trifunctional protein. Mutations in the genes encoding mitochondrial proteins res
Externí odkaz:
https://doaj.org/article/59ae9cfd806f4407af181bd7a78d517e
Autor:
Wenquan Hu, Zhong Liu, Valerie Salato, Paula E. North, Joyce Bischoff, Suresh N. Kumar, Zhi Fang, Sujith Rajan, M. Mahmood Hussain, Qing R. Miao
Publikováno v:
JCI Insight, Vol 6, Iss 3 (2021)
Infantile hemangioma is a vascular tumor characterized by the rapid growth of disorganized blood vessels followed by slow spontaneous involution. The underlying molecular mechanisms that regulate hemangioma proliferation and involution still are not
Externí odkaz:
https://doaj.org/article/e01edc80a8124f4bb805089613bbc913
Autor:
Joohyun Kim, MD, PhD, Catherine E. Hagen, MD, Suresh N. Kumar, PhD, Jong-In Park, PhD, Michael A. Zimmerman, MD, Johnny C. Hong, MD
Publikováno v:
Transplantation Direct, Vol 6, Iss 8, p e584 (2020)
Background. Cholestasis is a sign of hepatic ischemia-reperfusion injury (IRI), which is caused by the dysfunction of hepatocyte membrane transporters (HMTs). As transcriptional regulation of HMTs during oxidative stress is mediated by nuclear factor
Externí odkaz:
https://doaj.org/article/704f26ca2d4f4db3ace99ac650f7a013
Autor:
Karthikeyan Thirugnanam, Stephanie M. Cossette, Qiulun Lu, Shreya R. Chowdhury, Leanne M. Harmann, Ankan Gupta, Andrew D. Spearman, Dmitry L. Sonin, Michelle Bordas, Suresh N. Kumar, Amy Y. Pan, Pippa M. Simpson, Jennifer L. Strande, Erin Bishop, Ming‐Hui Zou, Ramani Ramchandran
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 8, Iss 22 (2019)
Background The SNRK (sucrose‐nonfermenting–related kinase) enzyme is critical for cardiac function. However, the underlying cause for heart failure observed in Snrk cardiac conditional knockout mouse is unknown. Methods and Results Previously, 6
Externí odkaz:
https://doaj.org/article/9425db3854dc4a599dccceb7725c602a
Autor:
Thiago Arzua, Yasheng Yan, Congshan Jiang, Sarah Logan, Reilly L. Allison, Clive Wells, Suresh N. Kumar, Richard Schäfer, Xiaowen Bai
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-1 (2021)
A Correction to this paper has been published: https://doi.org/10.1038/s41398-021-01214-z.
Externí odkaz:
https://doaj.org/article/08071854a11c43ba97ebbe2b1ac37bcc
Autor:
Shahram Eisa-Beygi, Meng-Ming Hu, Suresh N. Kumar, Brooke E. Jeffery, Ross F. Collery, Nghia (Jack) Vo, Bhawika S. Lamichanne, H. Joseph Yost, Matthew B. Veldman, Brian A. Link
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology.
BACKGROUND: The goal of this study was to identify and characterize cell-cell interactions that facilitate endothelial tip cell fusion downstream of BMP (bone morphogenic protein)-mediated venous plexus formation. METHODS: High resolution and time-la
Publikováno v:
Annals of Diagnostic Pathology. 59:151956
Enhancer of Zeste 2 (EZH2), a methyltransferase and an upregulated gene is an adverse prognosticator in prostate cancer. It catalyzes histone H3 lysine 27 trimethylation (H3K27me3) leading to repressive chromatin status (heterochromatin). Following d
Autor:
Karthikeyan, Thirugnanam, Stephanie M, Cossette, Qiulun, Lu, Shreya R, Chowdhury, Leanne M, Harmann, Ankan, Gupta, Andrew D, Spearman, Dmitry L, Sonin, Michelle, Bordas, Suresh N, Kumar, Amy Y, Pan, Pippa M, Simpson, Jennifer L, Strande, Erin, Bishop, Ming-Hui, Zou, Ramani, Ramchandran
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background The SNRK (sucrose‐nonfermenting–related kinase) enzyme is critical for cardiac function. However, the underlying cause for heart failure observed in Snrk cardiac conditional knockout mouse is unknown. Methods and Results Previously, 6
Autor:
Jonathan C. Jeschke, Christopher G. Mayne, Christopher L. DeCiantis, Suresh N. Kumar, William R. Drobyski, Nita H. Salzman, Calvin B. Williams
Publikováno v:
The Journal of Immunology. 200:118.19-118.19
Homeostasis in the ileum involves ongoing immune responses. To study how homeostatic processes of the ileum impact CD4+T cell responses, we used TCR transgenic tools to breed “Bigenic” mice that spontaneously produced CD4+T cells reactive to a mo