Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Suresh Karne"'
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 285:G822-G828
The pathological activation of proteases within the pancreatic acinar cell is critical to initiating pancreatitis. Stimulation of acinar cells with supraphysiological concentrations of the CCK analog caerulein (CER) leads to protease activation and p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8a54b4fa4cdab883e04edd32f5832c8
https://doi.org/10.1152/ajpgi.00213.2003
https://doi.org/10.1152/ajpgi.00213.2003
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 282:G501-G507
Activation of zymogens within the pancreatic acinar cell is an early feature of acute pancreatitis. Supraphysiological concentrations of cholecystokinin (CCK) cause zymogen activation and pancreatitis. The effects of the CCK analog, caerulein, and al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7efb900036851b33c44c425f3ba67fe1
https://doi.org/10.1152/ajpgi.00388.2001
https://doi.org/10.1152/ajpgi.00388.2001
Publikováno v:
The American Journal of Medicine. 107:387-390
locus ceruleus, since experimental bilateral pontine lesions that involve the peri-locus ceruleus produce REM sleep behavior disorder in animals (l6). Bisoprolol is a lipophilic agent that penetrates the blood-brain barrier and blocks pontomedullary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3260d5276081d78d377f5a24f52298fc
https://doi.org/10.1016/s0002-9343(99)00244-2
https://doi.org/10.1016/s0002-9343(99)00244-2
Autor:
Suresh Karne, Fred S. Gorelick
Publikováno v:
Surgical Clinics of North America. 79:699-710
Acute pancreatitis (AP) is a disease characterized by abdominal pain and elevations in the serum levels of amylase and lipase. 27 A key feature of AP is the elaboration of an inflammatory reaction, 36 which results in edema of the pancreas and extens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79ca5ef79dbbe21d6e979ac1fc8dd3b7
https://doi.org/10.1016/s0039-6109(05)70036-0
https://doi.org/10.1016/s0039-6109(05)70036-0
Publikováno v:
Proceedings of the National Academy of Sciences. 91:6133-6137
Using an expression cloning strategy, a high-affinity melatonin receptor cDNA has been isolated from Xenopus laevis dermal melanophores. Transient expression of the cDNA in COS-7 cells resulted in high-affinity 2-[125I]-iodomelatonin binding (Kd = 6.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a77f457eee091620b771435869dd0c1
https://doi.org/10.1073/pnas.91.13.6133
https://doi.org/10.1073/pnas.91.13.6133
Publikováno v:
Journal of Biological Chemistry. 268:19126-19133
We report here the presence of a receptor specific for endothelin-3 (termed ETc receptor or ETcR) on Xenopus laevis dermal melanophores. Activation of ETcR causes the dispersion of the pigment granules within the melanophores. The EC50 for ET-3 to in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::164044dada4b761bbd6935c7e13f9504
https://doi.org/10.1016/s0021-9258(17)46743-3
https://doi.org/10.1016/s0021-9258(17)46743-3
Autor:
Michael R. Lerner, Channa K Jayawickreme, Suresh Karne, Timothy S. McClintock, Marc N. Potenza, G F Graminski
Publikováno v:
Ciba Foundation Symposium 179-The Molecular Basis of Smell and Taste Transduction
Vertebrate olfactory receptors are members of the seven-transmembrane-domain G protein-coupled receptor family. They utilize intracellular signal transduction pathways which are activated by stimulation of odorant receptors and use the second messeng
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5fd10c0b23dbc33e237b74d87c642855
https://doi.org/10.1002/9780470514511.ch6
https://doi.org/10.1002/9780470514511.ch6
Autor:
Suresh Karne, Marc Quillan, Timothy S. McClintock, Alison Roby-Shemkovitz, Kristine Harris, Marc N. Potenza, Liquan Huang, Lina Golovyan, G F Graminski, Michael R. Lerner, Channa K Jayawickreme
Publikováno v:
American journal of therapeutics. 3(4)
A method for rapidly evaluating functional interactions between ligands and G-protein--coupled receptors has been developed. The technology is based on the ability of animals to change color by controlling the position of pigmented organelles within
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68777db50e6c8a38cac2cd1135c70a21
https://pubmed.ncbi.nlm.nih.gov/11862262
https://pubmed.ncbi.nlm.nih.gov/11862262
Publikováno v:
Gastroenterology. 120:A719-A719
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1adae9f8864c3fe680aba2b3fe84aa2e
https://doi.org/10.1016/s0016-5085(01)83579-4
https://doi.org/10.1016/s0016-5085(01)83579-4
Autor:
Masatoshi Makuuchi, Thomas R. Kolodecik, Taiichi Otani, Hiroshi Usui, Yasuhito Shimizu, Akira Matsukura, Takaaki Sugiki, Takeshi Takamoto, Fred S. Gorelick, Suresh Karne
Publikováno v:
Gastroenterology. 118:A158
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a66b05d719dce221278677ae2d460155
https://doi.org/10.1016/s0016-5085(00)82706-7
https://doi.org/10.1016/s0016-5085(00)82706-7