Výsledky vyhledávání - "Suresh K. Purushothaman"

Trm112p Is a 15-kDa Zinc Finger Protein Essential for the Activity of Two tRNA and One Protein Methyltransferases in Yeast

Autor: Léon Dirick, Bruno Lapeyre, Glenn R. Björk, Marie-Hélène Mazauric, Suresh K. Purushothaman

Publikováno v: Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2010, 285 (24), pp.18505-15. 〈10.1074/jbc.M110.113100〉
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2010, 285 (24), pp.18505-18515. ⟨10.1074/jbc.M110.113100⟩

International audience; The degenerate base at position 34 of the tRNA anticodon is the target of numerous modification enzymes. In Saccharomyces cerevisiae, five tRNAs exhibit a complex modification of uridine 34 (mcm(5)U(34) and mcm(5)s(2)U(34)), t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb9a8ae0da66b4af63c96ac15c38a69a
https://doi.org/10.1074/jbc.m110.113100

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Trm11p and Trm112p Are both Required for the Formation of 2-Methylguanosine at Position 10 in Yeast tRNA

Autor: Bruno Lapeyre, Henri Grosjean, Suresh K. Purushothaman, Janusz M. Bujnicki

Publikováno v: Molecular and Cellular Biology. 25:4359-4370

N(2)-Monomethylguanosine-10 (m(2)G10) and N(2),N(2)-dimethylguanosine-26 (m(2)(2)G26) are the only two guanosine modifications that have been detected in tRNA from nearly all archaea and eukaryotes but not in bacteria. In Saccharomyces cerevisiae, fo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ea3ecdbbcf6afef8c82875e30987726
https://doi.org/10.1128/mcb.25.11.4359-4370.2005

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Bioinformatics-Guided Identification and Experimental Characterization of Novel RNA Methyltransferas

Autor: Louis Droogmans, Bruno Lapeyre, Suresh K. Purushothaman, Henri Grosjean, Janusz M. Bujnicki

Publikováno v: Practical Bioinformatics ISBN: 9783540742678

Naturally occurring RNAs contain numerous chemically altered nucleosides. They are formed by enzymatic modification of the primary transcripts during the complex RNA maturation process. To date, a total of 96 structurally distinguishable modified nuc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::06a4e31a04f4a2115a6ea89fdb4cb392
https://doi.org/10.1007/978-3-540-74268-5_7

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Spb1p-directed formation of Gm2922 in the ribosome catalytic center occurs at a late processing stage

Autor: Bruno Lapeyre, Suresh K. Purushothaman

Publikováno v: Molecular cell. 16(4)

rRNA molecules undergo extensive posttranscriptional modification, predominantly 2'-O-ribose methylation and pseudouridine formation, both of which are guided by the numerous small nucleolar RNAs in eukaryotes. Here, we describe an exception to this

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b16a3e502ecb4936eeed0dde825082c3
https://pubmed.ncbi.nlm.nih.gov/15546625

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