Zobrazeno 1 - 10
of 122
pro vyhledávání: '"Suresh K, Mittal"'
Autor:
Ekramy E. Sayedahmed, Marcelo Valdemir Araújo, Taiana Tainá Silva-Pereira, Shubhada K. Chothe, Ahmed Elkashif, Marwa Alhashimi, Wen-Chien Wang, Andrea P. Santos, Meera Surendran Nair, Abhinay Gontu, Ruth Nissly, Antônio Francisco de Souza Filho, Mariana Silva Tavares, Marina Caçador Ayupe, Caio Loureiro Salgado, Érika Donizetti de Oliveira Candido, Danielle Bruna Leal Oliveira, Edison Luiz Durigon, Marcos Bryan Heinemann, Denise Morais da Fonseca, Chinnaswamy Jagannath, Ana Marcia Sá Guimarães, Suresh V. Kuchipudi, Suresh K. Mittal
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 30, Iss , Pp 194-207 (2023)
Because of continual generation of new variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), it is critical to design the next generation of vaccines to combat the threat posed by SARS-CoV-2 variants. We developed human adenovirus
Externí odkaz:
https://doaj.org/article/4546dbaeda5b4dfa95545d2dbef95e54
Autor:
Ekramy E. Sayedahmed, Nelly O. Elshafie, GuangJun Zhang, Sulma I. Mohammed, Suryaprakash Sambhara, Suresh K. Mittal
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionNonhuman adenoviral (AdV) gene delivery platforms have significant value due to their ability to elude preexisting AdV vector immunity in most individuals. Previously, we have demonstrated that intranasal (IN) immunization of mice with BA
Externí odkaz:
https://doaj.org/article/94c6a6041d594650abb015b716073724
Autor:
Ekramy E. Sayedahmed, Nelly O. Elshafie, Andrea P. dos Santos, Chinnaswamy Jagannath, Suryaprakash Sambhara, Suresh K. Mittal
Publikováno v:
Vaccines, Vol 12, Iss 2, p 157 (2024)
The nucleoprotein (NP) is a vital target for the heterosubtypic immunity of CD8+ cytotoxic T lymphocytes (CTLs) due to its conservation among influenza virus subtypes. To further enhance the T cell immunity of NP, autophagy-inducing peptide C5 (AIP-C
Externí odkaz:
https://doaj.org/article/5db201f60a3540b78f779c4abf24a943
Publikováno v:
Viruses, Vol 14, Iss 12, p 2727 (2022)
An adenoviral (AdV)-based vector system is a promising platform for vaccine development and gene therapy applications. Administration of an AdV vector elicits robust innate immunity, leading to the development of humoral and cellular immune responses
Externí odkaz:
https://doaj.org/article/9913642ee35247c0abff3956205e660e
Autor:
Caitlin D. Bohannon, Zachary Ende, Weiping Cao, Wadzanai P. Mboko, Priya Ranjan, Amrita Kumar, Margarita Mishina, Samuel Amoah, Shivaprakash Gangappa, Suresh K. Mittal, Jonathan F. Lovell, Adolfo García‐Sastre, Blaine A. Pfeifer, Bruce A. Davidson, Paul Knight, Suryaprakash Sambhara
Publikováno v:
Advanced Science, Vol 8, Iss 16, Pp n/a-n/a (2021)
Abstract Influenza infections cause several million cases of severe respiratory illness, hospitalizations, and hundreds of thousands of deaths globally. Secondary infections are a leading cause of influenza's high morbidity and mortality, and signifi
Externí odkaz:
https://doaj.org/article/404ee5401a084d95a30c1ea15b5a9472
Publikováno v:
Viruses, Vol 14, Iss 8, p 1684 (2022)
Influenza viruses are responsible for millions of cases globally and significantly threaten public health. Since pandemic and zoonotic influenza viruses have emerged in the last 20 years and some of the viruses have resulted in high mortality in huma
Externí odkaz:
https://doaj.org/article/f4c66ab2593146d4a852cec0902dd050
Publikováno v:
Clinical & Translational Immunology, Vol 10, Iss 10, Pp n/a-n/a (2021)
Abstract Since the development of the first vaccine against smallpox over two centuries ago, vaccination strategies have been at the forefront of significantly impacting the incidences of infectious diseases globally. However, the increase in the hum
Externí odkaz:
https://doaj.org/article/2d0493b19cb14e73a6c532391c408cd4
Autor:
Ekramy E. Sayedahmed, Ahmed O. Hassan, Rashmi Kumari, Weiping Cao, Shivaprakash Gangappa, Ian York, Suryaprakash Sambhara, Suresh K. Mittal
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 10, Iss , Pp 210-222 (2018)
Several human and nonhuman adenovirus (AdV) vectors including bovine AdV type 3 (BAdV-3) were developed as gene delivery vectors to supplement and/or elude human AdV (HAdV)-specific neutralizing antibodies (vector immunity). Here we evaluated the vac
Externí odkaz:
https://doaj.org/article/4840ace576694863bc75bc2475799085
Autor:
Weiping Cao, Margarita Mishina, Samuel Amoah, Wadzanai P. Mboko, Caitlin Bohannon, James McCoy, Suresh K. Mittal, Shivaprakash Gangappa, Suryaprakash Sambhara
Publikováno v:
Drug Delivery, Vol 25, Iss 1, Pp 773-779 (2018)
Avian influenza virus infection is a serious public health threat and preventive vaccination is the most cost-effective public health intervention strategy. Unfortunately, currently available unadjuvanted avian influenza vaccines are poorly immunogen
Externí odkaz:
https://doaj.org/article/bd29deac68df40f4a89554a8bf69ab77
Publikováno v:
Expert Review of Vaccines, Vol 16, Iss 11, Pp 1141-1154 (2017)
Introduction: Annual vaccination is one of the most efficient and cost-effective strategies to prevent and control influenza epidemics. Most of the currently available influenza vaccines are strong inducers of antibody responses against viral surface
Externí odkaz:
https://doaj.org/article/83447cefbaf74fb781a420462a15a75a