Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Suresh K, Mendu"'
Autor:
Michael S. Schappe, Marta E. Stremska, Gregory W. Busey, Taylor K. Downs, Philip V. Seegren, Suresh K. Mendu, Zachary Flegal, Catherine A. Doyle, Eric J. Stipes, Bimal N. Desai
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Efficient removal of apoptotic cells by phagocytosis underlies tissue development, wound repair, host defense and organ homeostasis. Here, authors identify TRPM7 as a regulator of cargo acidification and Ca2+ signaling during apoptotic cell clearance
Externí odkaz:
https://doaj.org/article/91b4d7f5e2564ec69283f69be2f00ae0
Autor:
Rochelle E. Fletcher, Natalia S. Nunes, Michael T. Patterson, Natasha Vinod, Shanzay M. Khan, Suresh K. Mendu, Xianghong Li, Alessandra de Paula Pohl, Lucas P. Wachsmuth, Hyoyoung Choo-Wosoba, Michael A. Eckhaus, David J. Venzon, Christopher G. Kanakry
Publikováno v:
Blood Adv
Posttransplantation cyclophosphamide (PTCy), given on days +3 and +4, reduces graft-versus-host disease (GVHD) after allogeneic hematopoietic cell transplantation (HCT), but its immunologic underpinnings are not fully understood. In a T-cell–replet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f209404a429cedb4583d3435bde76cfb
https://doi.org/10.1182/bloodadvances.2022007026
https://doi.org/10.1182/bloodadvances.2022007026
Autor:
Subramanian Senthivinayagam, Vlad Serbulea, Clint M. Upchurch, Renata Polanowska-Grabowska, Suresh K. Mendu, Srabani Sahu, Prathiba Jayaguru, Kevin W. Aylor, Mahendra D. Chordia, Limor Steinberg, Nathaniel Oberholtzer, Seichii Uchiyama, Noriko Inada, Ulrike M. Lorenz, Thurl E. Harris, Susanna R. Keller, Akshaya K. Meher, Alexandra Kadl, Bimal N. Desai, Bijoy K. Kundu, Norbert Leitinger
Publikováno v:
Molecular Metabolism, Vol 44, Iss , Pp 101130- (2021)
Objective: Brown adipose tissue (BAT) is specialized in thermogenesis. The conversion of energy into heat in brown adipocytes proceeds via stimulation of β-adrenergic receptor (βAR)-dependent signaling and activation of mitochondrial uncoupling pro
Externí odkaz:
https://doaj.org/article/3bac5da2881d485a8632564ecf041a48
Autor:
Michael T. Patterson, Shanzay M. Khan, Natalia S. Nunes, Rochelle E. Fletcher, Jing Bian, Ashley D. Hadjis, Michael A. Eckhaus, Suresh K. Mendu, Alessandra de Paula Pohl, David J. Venzon, Hyoyoung Choo-Wosoba, Kazusa Ishii, Haiying Qin, Terry J. Fry, Maggie Cam, Christopher G. Kanakry
Publikováno v:
Blood. 141:659-672
Relapse limits the therapeutic efficacy both of chimeric antigen receptor (CAR) T cells and allogeneic hematopoietic cell transplantation (allo-HCT). Patients may undergo these therapies sequentially to prevent or treat relapsed malignancy. However,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c01008114de1005258e673a76ca91af4
https://doi.org/10.1182/blood.2022016660
https://doi.org/10.1182/blood.2022016660
Autor:
Renata Polanowska-Grabowska, Srabani Sahu, Norbert Leitinger, Noriko Inada, Alexandra Kadl, Subramanian Senthivinayagam, Nathaniel P. Oberholtzer, Kevin W. Aylor, Susanna R. Keller, Ulrike M. Lorenz, Bimal N. Desai, Seichii Uchiyama, Vlad Serbulea, Thurl E. Harris, Limor Steinberg, Bijoy Kundu, Prathiba Jayaguru, Clint M Upchurch, Suresh K. Mendu, Akshaya K. Meher, Mahendra D. Chordia
Publikováno v:
Molecular Metabolism, Vol 44, Iss, Pp 101130-(2021)
Molecular Metabolism
Molecular Metabolism
Objective Brown adipose tissue (BAT) is specialized in thermogenesis. The conversion of energy into heat in brown adipocytes proceeds via stimulation of β-adrenergic receptor (βAR)-dependent signaling and activation of mitochondrial uncoupling prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::583445502d9ad837a62eb1dcce42ea6a
http://www.sciencedirect.com/science/article/pii/S2212877820302040
http://www.sciencedirect.com/science/article/pii/S2212877820302040
Autor:
Suresh K. Mendu, Marta E. Stremska, Bimal N. Desai, Julia K. Krupa, Clare A. Parker, Michael S. Schappe, Eric J. Stipes, Jason S. Rogers, Justin S. A. Perry, Emily K. Moser, Thomas J. Braciale
Publikováno v:
Sci Signal
The thymic development of regulatory T (T(reg)) cells, crucial suppressors of the responses of effector T (T(eff)) cells, is governed by the transcription factor FOXP3. Despite the clinical importance of T(reg) cells, there is a dearth of druggable m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d82adb853980e9002ca0667da87e572
https://doi.org/10.1126/scisignal.abb0619
https://doi.org/10.1126/scisignal.abb0619
Autor:
Peng Zhang, Xi Kang, Guangfu Wang, Bimal N. Desai, J. Julius Zhu, Suresh K. Mendu, Yajun Zhang, Yali Wang
Publikováno v:
Nature Neuroscience, 23, 1047-1050
Nature Neuroscience, 23, 9, pp. 1047-1050
Nat Neurosci
Nature Neuroscience, 23, 9, pp. 1047-1050
Nat Neurosci
Contains fulltext : 214411.pdf (Publisher’s version ) (Closed access)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b27823f93b09e1c27bb6efd6b1ef9171
http://hdl.handle.net/2066/214411
http://hdl.handle.net/2066/214411
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e42959 (2012)
γ-Aminobutyric acid (GABA) is the most prominent neuroinhibitory transmitter in the brain, where it activates neuronal GABA-A receptors (GABA-A channels) located at synapses and outside of synapses. The GABA-A receptors are primary targets of many c
Externí odkaz:
https://doaj.org/article/74c902eb16854b2997e215b9f92c15ae
Autor:
Bimal N. Desai, Eugene J. Barrett, Miranda E. Good, Leon J. DeLalio, Joshua T. Butcher, Ulrike Lorenz, Norbert Leitinger, Kodi S. Ravichandran, Suresh K. Mendu, Alexander W. Lohman, Ivan K. H. Poon, Christopher B. Medina, Yu-Hsin Chiu, Douglas A. Bayliss, Brant E. Isakson, Iris Z. Jaffe
Publikováno v:
Circulation Research. 122:606-615
Rationale: Resistant hypertension is a major health concern with unknown cause. Spironolactone is an effective antihypertensive drug, especially for patients with resistant hypertension, and is considered by the World Health Organization as an essent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77b629520f81c48669c2ba6b583a22f6
https://doi.org/10.1161/circresaha.117.312380
https://doi.org/10.1161/circresaha.117.312380
Autor:
Suresh K. Mendu, Bimal N. Desai, David J. Milan, Pui-ying Lam, Randall T. Peterson, Baohui Zheng, Hugo Padilla, Robert W. Mills
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Scientific Reports
Scientific Reports
Optogenetics is a powerful research approach that allows localized optical modulation of selected cells within an animal via the expression of genetically encoded photo-excitable ion channels. Commonly used optogenetic techniques rely on the expressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e77d2df7fee211d98cce20a97d7b6003
http://link.springer.com/article/10.1038/s41598-017-11791-z
http://link.springer.com/article/10.1038/s41598-017-11791-z