Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Suresh Guruswamy"'
Autor:
Levy Kopelovich, Suresh Guruswamy, Jagan M.R. Patlolla, Malisetty V. Swamy, Vernon E. Steele, Chinthalapally V. Rao
Supplementary Figure Legend from Inhibition of Azoxymethane-Induced Colorectal Cancer by CP-31398, a TP53 Modulator, Alone or in Combination with Low Doses of Celecoxib in Male F344 Rats
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a38daa7ca266b047287f22463f83a957
https://doi.org/10.1158/0008-5472.22380096
https://doi.org/10.1158/0008-5472.22380096
Autor:
Levy Kopelovich, Suresh Guruswamy, Jagan M.R. Patlolla, Malisetty V. Swamy, Vernon E. Steele, Chinthalapally V. Rao
Supplementary Figure 1 from Inhibition of Azoxymethane-Induced Colorectal Cancer by CP-31398, a TP53 Modulator, Alone or in Combination with Low Doses of Celecoxib in Male F344 Rats
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4964e5e25d131cd32368c341b73a0c42
https://doi.org/10.1158/0008-5472.22380099.v1
https://doi.org/10.1158/0008-5472.22380099.v1
Autor:
Levy Kopelovich, Suresh Guruswamy, Jagan M.R. Patlolla, Malisetty V. Swamy, Vernon E. Steele, Chinthalapally V. Rao
Tumor suppressor p53 plays a major role in colorectal cancer development. The present study explores the effects of p53-modulating agent CP-31398 alone and combined with celecoxib on azoxymethane-induced aberrant crypt foci (ACF) and colon adenocarci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80b6509a773caf125a4f4732f8ffb662
https://doi.org/10.1158/0008-5472.c.6499449.v1
https://doi.org/10.1158/0008-5472.c.6499449.v1
Autor:
Yuhong Wang, Yuting Zhang, Qian Li, Suresh Guruswamy, Zhongjie Sun, Doris M. Benbrook, Chinthalapally V. Rao, Altaf Mohammed
Publikováno v:
Cancer Prevention Research. 6:908-916
The occurrence of intestinal polyps in people at high risk for developing colorectal cancer provides an opportunity to test the efficacy of chemoprevention agents. In this situation of treating otherwise healthy people, the potential for toxicity mus
Autor:
Jagan M.R. Patlolla, Chinthalapally V. Rao, Vernon E. Steele, Malisetty V. Swamy, Levy Kopelovich, Suresh Guruswamy
Publikováno v:
Cancer Research. 69:8175-8182
Tumor suppressor p53 plays a major role in colorectal cancer development. The present study explores the effects of p53-modulating agent CP-31398 alone and combined with celecoxib on azoxymethane-induced aberrant crypt foci (ACF) and colon adenocarci
Publikováno v:
Gene Regulation and Systems Biology, Vol 2, Pp 163-176 (2008)
Gene Regulation and Systems Biology
Gene Regulation and Systems Biology, Vol 2 (2008)
Gene Regulation and Systems Biology
Gene Regulation and Systems Biology, Vol 2 (2008)
Colorectal cancer is the leading cause of cancer related deaths in the United States. Although it is preventable, thousands of lives are lost each year in the U.S. to colorectal cancer than to breast cancer and AIDS combined. In colon cancer, the for
Publikováno v:
International Journal of Cancer. 122:25-30
S-adenosyl L-methionine (SAM) is a universal methyl group donor to various intermediary metabolites, hormones, proteins, neurotransmitters, phospholipids and nucleic acids. Deficiency of folate, which plays a role in the synthesis of SAM leads to inc
Autor:
Doris M. Benbrook, Suresh Guruswamy
Publikováno v:
American Journal of Pharmacology and Toxicology. 1:87-93
Treatment of ovarian cancer with cisplatin-based chemotherapy is highly toxic and is often followed by cancer recurrence. Repeated treatments with cisplatin frequently result in the development of resistance to this drug. Drugs with low toxicity that
Autor:
Suresh Guruswamy, Teresa L. Rutledge, Todd Tillmanns, Doris M. Benbrook, Natalie S. Gould, Scott A. Kamelle
Publikováno v:
Gynecologic Oncology. 97:142-150
Objective. Current therapy for cervical cancer includes radiation therapy. Retinoic acid (RA) can increase the sensitivity of cervical cancer cell lines to radiation. The mechanism of this sensitization may not involve the p53 protein because the hum
Autor:
Doris M. Benbrook, Ginger J. Gardner, David B. Brown, Michael J. Birrer, Suresh Guruswamy, Aridam Dhar, Shengquan Liu, K. Darrell Berlin, Chad W. Brown
Publikováno v:
Journal of Medicinal Chemistry. 47:999-1007
Regulation of growth, differentiation, and apoptosis by synthetic retinoids can occur through mechanisms that are dependent and independent of their ability to bind and activate nuclear retinoic acid receptors. The objective of this study was to dete