Výsledky vyhledávání - "Suresh Gadher"

Dihydroorotate Dehydrogenase Is a High Affinity Binding Protein for A77 1726 and Mediator of a Range of Biological Effects of the Immunomodulatory Compound

Autor: S. Spinella-Jaegle, A. B. Hambleton, Adam P. Curnock, P. Hambleton, K. Woodward, J.-M. Bruneau, Erik Ruuth, Yea Christopher Martyn, E. A. Kuo, O. Courtin, Robert Westwood, D. Moss, T. A. Thomson, Catherine Sautes, Richard A. Williamson, Suresh Gadher, Peter A. Robson, P. Morand, T. Hercend

Publikováno v: Journal of Biological Chemistry. 270:22467-22472

A protein with high affinity (Kd 12 nM) for the immunomodulatory compound A77 1726 has been isolated from mouse spleen and identified as the mitochondrial enzyme dihydroorotate dehydrogenase (EC 1.3.3.1). The purified protein had a pI 9.6-9.8 and a s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6b93638a1f9d60183442d6f3f2cc101
https://doi.org/10.1074/jbc.270.38.22467

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