Výsledky vyhledávání - "Suresh Dheerendra"

Antibody-mediated activation of the FGFR1/Klothoβ complex corrects metabolic dysfunction and alters food preference in obese humans

Autor: Chin Wong, Thomas Gelzleichter, Junichiro Sonoda, Amos Baruch, Linda Morrow, Suresh Dheerendra, Leslie W. Chinn, Richard Boismenu, Eric Wakshull, Maria E. Wilson, Puneet S. Arora, Shan Chen, Anjali Vaze, Johnny Gutierrez, Nicholas Lewin-Koh

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America

Significance Fibroblast growth factor 21 (FGF21) controls metabolic organ homeostasis and eating behavior via FGF receptor 1/Klothoβ (FGFR1/KLB) complexes. Here we show that a bispecific anti-FGFR1/KLB agonist antibody, BFKB8488A, mimics the actions

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecb1e6fc5999a3fd66bc3ad16e368b18
https://doi.org/10.1073/pnas.2012073117

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Intravenous carbamazepine as short-term replacement therapy for oral carbamazepine in adults with epilepsy: Pooled tolerability results from two open-label trials

Autor: Dwain Tolbert, Victor Biton, Pavel Klein, Ihor Bekersky, Guangbin Peng, Uwa Kalu, Suresh Dheerendra, James C. Cloyd, Jonathan J. Halford, Deborah Lee

Publikováno v: Epilepsia. 56(6)

SummaryObjective To report tolerability findings and maintenance of seizure control from a pooled analysis of phase I open-label trial OV-1015 (NCT01079351) and phase III study 13181A (NCT01128959). Methods Patients receiving a stable oral dosage of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d9f5ee2a12077b676c60c2bfaa8082c
https://pubmed.ncbi.nlm.nih.gov/25912051

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