Case report: A novel HNF1A variant linked to gestational diabetes, congenital hyperinsulinism, and diazoxide hypersensitivity

Autor: Suresh Chandran, Deepti Verma, Victor Samuel Rajadurai, Fabian Yap

Publikováno v: Frontiers in Endocrinology, Vol 15 (2024)

Diazoxide (DZX) remains the first-line medication for the treatment of prolonged and persistent forms of hyperinsulinemic hypoglycemia (HH). In nearly 40%–50% of cases of HH, the genetic mechanism is unidentified. Almost half of the infants with pe

Externí odkaz: https://doaj.org/article/621c0faad131461e86f83f7d72e65068

Secondary prevention with a structured semi-interactive stroke prevention package in INDIA (SPRINT INDIA): a multicentre, randomised controlled trial

Autor: Jeyaraj Durai Pandian, Mahesh Pundlik Kate, Padmavathyamma Narayanapillai Sylaja, Dheeraj Khurana, Vijaya Pamidimukkala, Biman Kanti Ray, Vivek Keshavan Nambiar, Sanjith Aaron, Gaurav Kumar Mittal, Sundarachary Nagarjunakonda, Aparna Ramakrishna Pai, Sankar Prasad Gorthi, Somasundaram Kumaravelu, Yerasu Muralidhar Reddy, Sunil Narayan, Nomal Chandra Borah, Rupjyoti Das, Girish Baburao Kulkarni, Vikram Huded, Thomas Mathew, M Vasantha Padma Srivastava, Rohit Bhatia, Pawan Tarkeshwarnath Ojha, Jayanta Roy, Sherly Mary Abraham, Anand Girish Vaishnav, Arvind Sharma, Shaikh Afshan Jabeen, Abhishek Pathak, Sanjeev Kumar Bhoi, Sudhir Sharma, Sulena Sulena, Aralikatte Onkarappa Saroja, Neetu Ramrakhiani, Madhusudhan Byadarahalli Kempegowda, Sapna Erat Sreedharan, Gautam Das, Tina George, Ivy Sebastian, Rajeshwar Sahonta, Shyam Krishnakumar Jaiswal, Lalitha Pidaparthi, Rajeshwari Aghoram, Jemin Jeyachandra Webster, Rakesh Hasmukhlal Shah, Menka Jha, Karkal Ravishankar Niak, Deepti Arora, Shweta Jain Verma, Rahul Huilgol, Aneesh Dhasan, Vishnu Renjith, Himani Khatter, Prabhakaran Sarma, Sadasivan Laila Visakh, Sukhmandeep Kaur, Tagallamudi Nagamalleswara Rao, Venkatesh Dumpala, Gargi Podder, Arindam Biswas, Karthika Rani, Nishanthini Dhamodharan, Shilpa Sekhar, Satish Kumar Chinka, Varsha Aroor Prabhu, Farhaz Zaha, Sarvotham Ramanathan, Deepika Pabbu, Nupur Choudhury, Ramya Ramanathan, Saji K James, Neha Kuthalia, Sakshi Sharma, Mayuri Ramchandra Gaikwad, Purbita Sen, Sumita Basumatary, Rachana Dhruvesh Bhatt, Dipal Patel, Mareena Cyriac, Sasmita Swain, Narinder Kumar, Amaresh Kurubara, Devang Sharma, Meenakshi Sharma, Rupinder Dhaliwal, Jagarlapudi Murali Krishna Murthy, Prem Pais, Denis Xavier, Parthasarathy Satishchandra, Subash Kaul, Vishnubhatla Sreenivas, Suresh Chandran, Rajneesh Kumar Calton, Jacob George

Publikováno v: The Lancet Global Health, Vol 11, Iss 3, Pp e425-e435 (2023)

Summary: Background: There is a high burden of stroke, including recurrent stroke, in India. We aimed to assess the effect of a structured semi-interactive stroke prevention package in patients with subacute stroke to reduce recurrent strokes, myocar

Externí odkaz: https://doaj.org/article/819e7dda9303467eb8bf6e6fae8e45d6

Necrotizing pneumonia requiring prolonged extracorporeal membrane oxygenation: Pushing the boundaries in pediatric ECMO

Autor: Pravin R. R., Suresh Chandran, Yi Hua Tan, Biju Thomas, Jan Hau Lee, Anuradha P. Menon, Kim Kiat Ong, Arun Kumar Pugalenthi

Publikováno v: Clinical Case Reports, Vol 10, Iss 7, Pp n/a-n/a (2022)

Abstract Extracorporeal membrane oxygenation (ECMO) is a life‐saving rescue therapy used in acute respiratory failure refractory to invasive mechanical ventilation. Recent studies on positive outcomes of extended ECMO therapy are promising. We desc

Externí odkaz: https://doaj.org/article/d0031ee3b40b47d591e2ab1a2a4af01a

Constriction ring of the penis in a newborn infant: A rare form of amniotic band syndrome

Autor: Yu Shan Ting, Renisha Paul Mukkam, Suresh Chandran

Publikováno v: Clinical Case Reports, Vol 10, Iss 3, Pp n/a-n/a (2022)

Abstract The amniotic band comprises disrupted amnion strands causing entrapment or entanglement of various fetal parts resulting in a spectrum of anomalies from digital band constriction or amputation to severe craniofacial/visceral defects and even

Externí odkaz: https://doaj.org/article/cd993572a230420db5a002620d6d168a

A feed-centric hypoglycaemia pathway ensures appropriate care escalation in at-risk infants

Autor: Victor Samuel Rajadurai, Suresh Chandran, Fabian Yap, Jia Xuan Siew, Mei Chien Chua, Rachel Wei Shan Lim

Publikováno v: BMJ Open Quality, Vol 10, Iss 4 (2021)

Background There is a lack of clarity of what constitutes the starting point of a clinical pathway for infants at-risk of hypoglycaemia. Glucose-centric pathways (GCP) identify low glucose in the first 2 hours of life that may not represent clinical

Externí odkaz: https://doaj.org/article/4f12fb3b6d2b41d4a0b428e982e5363e