Zobrazeno 1 - 10
of 871
pro vyhledávání: '"Suresh C, Tyagi"'
Autor:
Suresh C. Tyagi
Publikováno v:
Antioxidants, Vol 13, Iss 10, p 1225 (2024)
Patients with Alzheimer’s disease and related dementia (ADRD) are faced with a formidable challenge of focal amyloid deposits and cerebral amyloid angiopathy (CAA). The treatment of amyloid deposits in ADRD by targeting only oxidative stress, infla
Externí odkaz:
https://doaj.org/article/c39dccbf42b3427ea4cc25cb59dc9208
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 16, p 8780 (2024)
Heart failure (HF) is a significant global healthcare burden with increasing prevalence and high morbidity and mortality rates. The diagnosis and management of HF are closely tied to ejection fraction (EF), a crucial parameter for evaluating disease
Externí odkaz:
https://doaj.org/article/2d46876e456c41bda2c6f0058440861b
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-18 (2022)
Abstract Diabetic nephropathy is characterized by excessive accumulation of extracellular matrix (ECM) leading to renal fibrosis, progressive deterioration of renal function, and eventually to end stage renal disease. Matrix metalloproteinases (MMPs)
Externí odkaz:
https://doaj.org/article/aa7c8a5b1197499ab9c032ee5471876e
Autor:
Mahavir Singh, Sathnur Pushpakumar, Yuting Zheng, Rubens P. Homme, Irina Smolenkova, Sri Prakash L. Mokshagundam, Suresh C. Tyagi
Publikováno v:
Physiological Reports, Vol 10, Iss 16, Pp n/a-n/a (2022)
Abstract Ketone bodies (KB) serve as the food for mitochondrial biogenetics. Interestingly, probiotics are known to promote KB formation in the gut (especially those that belong to the Lactobacillus genus). Furthermore, Lactobacillus helps produce fo
Externí odkaz:
https://doaj.org/article/fe138af1462448f78b23570c045ce853
Autor:
Sathnur Pushpakumar, Mahavir Singh, Yuting Zheng, Oluwaseun E. Akinterinwa, Sri Prakash L. Mokshagundam, Utpal Sen, Dinesh K. Kalra, Suresh C. Tyagi
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 8, p 7302 (2023)
Renal denervation (RDN) protects against hypertension, hypertrophy, and heart failure (HF); however, it is not clear whether RDN preserves ejection fraction (EF) during heart failure (HFpEF). To test this hypothesis, we simulated a chronic congestive
Externí odkaz:
https://doaj.org/article/54dbaf0ccec348598bbdd50396c0c4bb
Autor:
Suresh C. Tyagi, Sathnur Pushpakumar, Utpal Sen, Sri Prakash L. Mokshagundam, Dinesh K. Kalra, Mohamed A. Saad, Mahavir Singh
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 1, p 287 (2022)
Although progressive wasting and weakness of respiratory muscles are the prominent hallmarks of Duchenne muscular dystrophy (DMD) and long-COVID (also referred as the post-acute sequelae of COVID-19 syndrome); however, the underlying mechanism(s) lea
Externí odkaz:
https://doaj.org/article/1ec472bb64554349b5238ac6307ed6ec
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
During acute heart failure (HF), remote ischemic conditioning (RIC) has proven to be beneficial; however, it is currently unclear whether it also extends benefits from chronic congestive, cardiopulmonary heart failure (CHF). Previous studies from our
Externí odkaz:
https://doaj.org/article/2713615b6ace4a668f5506e3dba71bcc
Autor:
Akash K. George, Rubens P. Homme, Avisek Majumder, Anwesha Laha, Naira Metreveli, Harpal S. Sandhu, Suresh C. Tyagi, Mahavir Singh
Publikováno v:
International Journal of Ophthalmology, Vol 12, Iss 5, Pp 754-764 (2019)
AIM: To investigate the applications of hydrogen sulfide (H2S) in eye-specific ailments in mice. METHODS: Heterozygous cystathionine-β-synthase (CBS+/-) and wild-type C57BL/6J (WT) mice fed with or without high methionine diet (HMD) were administe
Externí odkaz:
https://doaj.org/article/c082792c7bf14bb2a1d914a5f0235ab5
Autor:
Dragana Stanisic, Nevena Jeremic, Suravi Majumder, Sathnur Pushpakumar, Akash George, Mahavir Singh, Suresh C. Tyagi
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
The gut microbiome has a very important role in human health and its influence on the development of numerous diseases is well known. In this study, we investigated the effect of high fat diet (HFD) on the onset of dysbiosis, gingival blood flow decr
Externí odkaz:
https://doaj.org/article/cae3db0e21924d42a1c5130c8bd55451
Autor:
Mahavir Singh, Shanna J. Hardin, Akash K. George, Wintana Eyob, Dragana Stanisic, Sathnur Pushpakumar, Suresh C. Tyagi
Publikováno v:
Frontiers in Physiology, Vol 11 (2021)
Although a high-fat diet (HFD) induces gut dysbiosis and cardiovascular system remodeling, the precise mechanism is unclear. We hypothesize that HFD instigates dysbiosis and cardiac muscle remodeling by inducing matrix metalloproteinases (MMPs), whic
Externí odkaz:
https://doaj.org/article/893c54ef41434bd7811959192326505e