Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Suresh, Narva"'
Synthesis and Evaluation of Biphenyl-1,2,3-Triazol-Benzonitrile Derivatives as PD-1/PD-L1 Inhibitors
Publikováno v:
ACS Omega, Vol 5, Iss 33, Pp 21181-21190 (2020)
Externí odkaz:
https://doaj.org/article/1fe906a05ef342a2aa261a7382266c55
Autor:
Nagesh, Hunsur Nagendra, Suresh, Narva, Mahalakshmi Naidu, Kalaga, Arun, Boyineni, Padma Sridevi, Jonnalagadda, Sriram, Dharmarajan, Yogeeswari, Perumal, Chandra Sekhar, Kondapalli Venkata Gowri
Publikováno v:
In European Journal of Medicinal Chemistry 3 March 2014 74:333-339
Autor:
Suresh, Narva, Nagesh, Hunsur Nagendra, Renuka, Janupally, Rajput, Vikrant, Sharma, Rashmi, Khan, Inshad Ali, Kondapalli Venkata Gowri, Chandra Sekhar
Publikováno v:
In European Journal of Medicinal Chemistry 7 January 2014 71:324-332
Autor:
Huijuan Mao, Suresh Narva, Xiaoyin Zhao, Yoshimasa Tanaka, Chuanxin Guo, Xuqiong Xiong, Wang Ming, Xudong Ma, Kang Zhou, Wen Zhang, Yanling Wu, Jiachun Liu, Hiroshi Sugiyama
Publikováno v:
Journal of Medicinal Chemistry. 64:6021-6036
In recent years, PD-1 immune checkpoint inhibitors based on monoclonal antibodies have revolutionized cancer therapy, but there still exist unresolved issues, such as the high cost, the relatively low response rates, and so on, compared with small-mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::852686cbb60fba8dd38ead7916d18378
https://doi.org/10.1021/acs.jmedchem.1c00120
https://doi.org/10.1021/acs.jmedchem.1c00120
Publikováno v:
Mini-Reviews in Medicinal Chemistry. 19:1517-1530
At present, cancers have been causing deadly fears to humans and previously unpredictable losses to health. Especially, lung cancer is one of the most common causes of cancer-related mortality accounting for approximately 15% of all cancer cases worl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f4b47bcf4259945fbbf84518d50d3d5
https://doi.org/10.2174/1389557519666190312152358
https://doi.org/10.2174/1389557519666190312152358
Autor:
Cheng Mei, Xiaoyin Zhao, Suresh Narva, Xuqiong Xiong, Hu Xiaolin, Kang Zhou, Jiachun Liu, Yanling Wu, Wen Zhang
Publikováno v:
European Journal of Medicinal Chemistry. 178:484-499
In our work, 19 novel 4,5-diazafluorene derivatives (11a-d, 12a-d, 13a-d, 14a-c, 15c, 16a-c) bearing a 1,3-disubstituted pyrazol/thioxothiazolidinone or thioxothiazolidinone-oxadiazole moieties were designed, synthesized, preliminarily explored for t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::220e7123e3b31bf0dfc3fae60ff52432
https://doi.org/10.1016/j.ejmech.2019.06.012
https://doi.org/10.1016/j.ejmech.2019.06.012
Synthesis and Evaluation of Biphenyl-1,2,3-Triazol-Benzonitrile Derivatives as PD-1/PD-L1 Inhibitors
Publikováno v:
ACS Omega
ACS Omega, Vol 5, Iss 33, Pp 21181-21190 (2020)
ACS Omega, Vol 5, Iss 33, Pp 21181-21190 (2020)
In this study, we designed and synthesized a series of 3-(4-((5-((2-methylbiphenyl-3-yl) methoxy)-2-(piperazin-1-ylmethyl)phenoxy)methyl)-1H-1,2,3-triazol-1-yl)benzonitrile derivatives and examined the effect of the compounds on the interaction betwe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbe1034c0ee74b107f0a3a1efe629eca
https://pubmed.ncbi.nlm.nih.gov/32875254
https://pubmed.ncbi.nlm.nih.gov/32875254
Autor:
Nishant Jain, Mallika Alvala, Surendar Chitti, Suresh Amaroju, Suresh Narva, Debanjan Bhattacharjee, Chandra Sekhar Kondapalli Venkata Gowri, Sridhar Goud
Publikováno v:
Journal of Heterocyclic Chemistry. 56:520-532
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4611d37444d395f752f76316210724d3
https://doi.org/10.1002/jhet.3427
https://doi.org/10.1002/jhet.3427
Autor:
Wen Zhang, Shi-Kun Jiang, Minrui Liu, Wang Ming, Ling Xu, Suresh Narva, Yanling Wu, Annoor Awadasseid
Publikováno v:
Tetrahedron Letters. 73:153111
Coumarins are naturally evolving molecules that have a wide variety of activities. In medical chemistry and chemical biology, their structural and physicochemical properties make them a suitable scaffold. Herein, we designed and synthesized novel cou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f7e5b6a6453c91ed1133a84c02d57ac4
https://doi.org/10.1016/j.tetlet.2021.153111
https://doi.org/10.1016/j.tetlet.2021.153111
Publikováno v:
Tetrahedron Letters. 68:152908
A series of imidazo[1,2-f]phenanthridine derivatives were synthesized from phenanthridin-6-amine and aldehydes through sulfur endorsed oxidative cyclization reaction under a metal- and base-free condition with atom economy strategy and evaluated thei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c15c2b0358bf7cd46189cf67af76ac39
https://doi.org/10.1016/j.tetlet.2021.152908
https://doi.org/10.1016/j.tetlet.2021.152908