Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Surendran Mahalingam"'
Autor:
James Storer, Jürgen Schwarze, Ali Zaid, Ralph A. Tripp, Sharyn Tauro, Theo P. Sloots, Rene Alvarez, Michael D. Nissen, Surendran Mahalingam
Publikováno v:
Microbes and Infection
Human metapneumovirus (HMPV) is a recently discovered pathogen first identified in respiratory specimens from young children suffering from clinical respiratory syndromes ranging from mild to severe lower respiratory tract illness. HMPV has worldwide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::867272c50379c2a91bda128412c6e060
https://doi.org/10.1016/j.micinf.2005.07.001
https://doi.org/10.1016/j.micinf.2005.07.001
Publikováno v:
Trends in Immunology. 25:636-639
The World Health Organization (WHO) announced the eradication of smallpox twenty-five years ago this month. This conquest of an infectious disease, which has been the bane of humankind for centuries, still stands as the WHO's greatest achievement. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2eeb559bc0cb9a8796a4143bf7eac919
https://doi.org/10.1016/j.it.2004.10.002
https://doi.org/10.1016/j.it.2004.10.002
Autor:
Debra D. Donaldson, Yeping Cai, Klaus I. Matthaei, Dianne C. Webb, Surendran Mahalingam, Paul S. Foster
Publikováno v:
European Journal of Immunology. 33:3377-3385
The pathogenesis of human asthma and the development of key features of pulmonary allergy in mouse models has been critically linked to IL-13. Analyses of the receptor components employed by IL-13 have shown that delivery of this cytokine to the airw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14b42f8f181a7040bd67244bb7f82ce9
https://doi.org/10.1002/eji.200324178
https://doi.org/10.1002/eji.200324178
Autor:
Marc E. Rothenberg, Simon P. Hogan, Sam M. Pope, Ming Yang, Patricia C. Fulkerson, Ian G. Young, Surendran Mahalingam, Paul S. Foster, Lindsay A. Dent, Klaus I. Matthaei, Nives Zimmermann
Publikováno v:
Journal of Allergy and Clinical Immunology. 112:935-943
Background Eotaxin-2 is a member of the eotaxin subfamily of CC chemokines that display eosinophil-specific, chemotactic properties and has been associated with allergic disorders. However, the contribution of eotaxin-2 to the development of defined
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cc80b46be6a6fbdb627cd73312f82ac
https://doi.org/10.1016/j.jaci.2003.08.010
https://doi.org/10.1016/j.jaci.2003.08.010
Autor:
Richard L. Stevens, Gregory Katsoulotos, Shinsuke Yasuda, Surendran Mahalingam, Paul S. Foster, Elizabeth A. Mellor, Guang W. Wong, Jian C. Qi, Steven A. Krilis, Joshua A. Boyce, Lixin Li
Publikováno v:
Journal of Biological Chemistry. 277:41906-41915
Transmembrane tryptase (TMT)/tryptase γ is a membrane-bound serine protease stored in the secretory granules of human and mouse lung mast cells (MCs). We now show that TMT reaches the external face of the plasma membrane when MCs are induced to degr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a321373fc2c07cc771dc2c50e69c6df0
https://doi.org/10.1074/jbc.m205868200
https://doi.org/10.1074/jbc.m205868200
Publikováno v:
Journal of Leukocyte Biology. 72:429-439
Virus infection presents a significant challenge to host survival. The capacity of the virus to replicate and persist in the host is dependent on the status of the host antiviral defense mechanisms. The study of antiviral immunity has revealed efecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d99519a2b3f28b9b694cfcbb89b1bcc
https://doi.org/10.1189/jlb.72.3.429
https://doi.org/10.1189/jlb.72.3.429
Autor:
Surendran Mahalingam
Publikováno v:
Graft. 5:277-293
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87128582fc6527b1473b0897f9b09699
https://doi.org/10.1177/1522162802005005002
https://doi.org/10.1177/1522162802005005002
Autor:
Marc E. Rothenberg, Joachim Kuehr, Simon P. Hogan, Ming Yang, Dianne C. Webb, Lindsay A. Dent, Surendran Mahalingam, Paul S. Foster, Klaus I. Matthaei, Joerg Mattes, Andrew N. J. McKenzie, Aulikki Koskinen, Ian G. Young, Ljubov Simson
Publikováno v:
The Journal of Experimental Medicine
Interleukin (IL)-5 and IL-13 are thought to play key roles in the pathogenesis of asthma. Although both cytokines use eotaxin to regulate eosinophilia, IL-13 is thought to operate a separate pathway to IL-5 to induce airways hyperreactivity (AHR) in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1576a8c6f5d370be74033ad9c571f84
https://doi.org/10.1084/jem.20020009
https://doi.org/10.1084/jem.20020009
Autor:
Nicholas H R Hamilton, Alistair J. Ramsay, Surendran Mahalingam, Ian A. Ramshaw, Scott Thomson, Joanne Banyer, Andrew J. Hapel
Publikováno v:
Scandinavian Journal of Immunology. 55:53-60
Murine interferon-inducible T cell alpha chemokine (I-TAC) is a potent non-ELR Cys-X-Cys (CXC) chemokine that predominantly attracts activated T lymphocytes and binds to the receptor CXCR3. Using semiquantitative reverse transcription–polymerase ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd1adb2c1c4e513adbde1693639a1c15
https://doi.org/10.1046/j.0300-9475.2001.01019.x
https://doi.org/10.1046/j.0300-9475.2001.01019.x
Autor:
Kiyoshi Takeda, Paul S. Foster, Shizuo Akira, Gunasegaran Karupiah, Surendran Mahalingam, Klaus I. Matthaei
Publikováno v:
Proceedings of the National Academy of Sciences. 98:6812-6817
We inoculated BALB/c mice deficient in STAT6 (STAT6−/−) and their wild-type (wt) littermates (STAT6+/+) with the natural mouse pathogen, ectromelia virus (EV). STAT6−/−mice exhibited increased resistance to generalized infection with EV when
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c050bd1827b575d20d3afb034f33c26c
https://doi.org/10.1073/pnas.111151098
https://doi.org/10.1073/pnas.111151098