Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Surendra N. Pandeya"'
Autor:
Surendra N. Pandeya
Publikováno v:
Acta Pharmaceutica. 62:263-286
During the last fifteen years, semicarbazones have been extensively investigated for their anticonvulsant properties. 4-(4-Flurophenoxy) benzaldehyde semicarbazone (C0102862, V102862) was discovered as a lead molecule and is being developed as a pote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebad82263dd93f9654019b1b078180aa
https://doi.org/10.2478/v10007-012-0030-1
https://doi.org/10.2478/v10007-012-0030-1
Autor:
Ven L. Narayanan, Surendra N. Pandeya, Anthony B. Mauger, Edward A. Sausville, Perumal Yogeeswari
Publikováno v:
Arzneimittelforschung. 52:103-108
4-Bromophenyl semicarbazone derivatives have been synthesized and their chemical structures have been confirmed by means of their IR, 1H-NMR data and by elemental analyses. The in vitro evaluation in the 3-cell line, one dose primary anticancer assay
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc809fc538514d056d48b4c597d37633
https://doi.org/10.1055/s-0031-1299864
https://doi.org/10.1055/s-0031-1299864
Publikováno v:
Medicinal Chemistry Research. 21:2428-2442
A series of 2-[2-(substituted)hydrazinyl]-1,3-benzothiazole and 2-(1,3-benzothiazol-2-ylsulfanyl)-N′-(substituted)acetohydrazide were designed and synthesized keeping in view the structural requirement of pharmacophore and evaluated for anticonvuls
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f79736b6de746d81a8cb3f8496bb888d
https://doi.org/10.1007/s00044-011-9768-0
https://doi.org/10.1007/s00044-011-9768-0
Publikováno v:
Scientia Pharmaceutica
Volume 76
Issue 4
Pages 621-636
Volume 76
Issue 4
Pages 621-636
A series of N-methyl/acetyl 5-(un)-substituted isatin-3-semicarbazones were screened for anticonvulsant and sedative-hypnotic activities. The results revealed that protection was obtained in all the screens i.e., Maximal electroshock, (MES) subcutane
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9662be4987e10a8f89c6ce31761791af
https://doi.org/10.3797/scipharm.0806-14
https://doi.org/10.3797/scipharm.0806-14
Publikováno v:
Pharmaceutical Chemistry Journal. 41:302-307
Several semicarbazones of acetophenone and p-chloroacetophenone Mannich bases were designed and synthesized to meet the pharmacophore requirements essential for anticonvulsant activity. Mannich bases of acetophenone and p-chloroacetophenone were prep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6fedb3a3e35130a3cd9748e05afe0ce5
https://doi.org/10.1007/s11094-007-0068-4
https://doi.org/10.1007/s11094-007-0068-4
Autor:
Md. Faiz Arshad, Suroor A. Khan, Arpana Rana, James P. Stables, Surendra N. Pandeya, Nadeem Siddiqui, Mahfuz Alam, Mashooq A. Bhat
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 17:255-259
A series of sulphonamide derivatives (1-11) were synthesized in good yield and evaluated for their possible anticonvulsant activity and neurotoxic study. The structures of the synthesized compounds were confirmed on the basis of their spectral data a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::005dd7e50974efaaffe2c371a50c6acd
https://doi.org/10.1016/j.bmcl.2006.09.053
https://doi.org/10.1016/j.bmcl.2006.09.053
Publikováno v:
European Journal of Medicinal Chemistry. 35:249-255
Mannich bases of norfloxacin were synthesized by reacting them with formaldehyde and several isatin derivatives. Their chemical structures have been confirmed by means of their IR, 1H-NMR data and by elemental analysis. Investigation of in vitro anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::274c2bf60531462245729989c32dcc8c
https://doi.org/10.1016/s0223-5234(00)00125-2
https://doi.org/10.1016/s0223-5234(00)00125-2
Autor:
Surendra N. Pandeya, Perumal Yogeeswari, Dharmarajan Sriram, Myriam Witvrouw, Christophe Pannecouque, E. De Clercq
Publikováno v:
Chemotherapy. 45:192-196
The effect of about 12 new compounds of Mannich bases of isatin against HIV-1 (IIIB) and HIV-2 (ROD) strains in MT 4 cells was studied. The screening method employed was MTT. In initial studies, one compound has shown maximum protection of 16% in sub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f50e3d39d1c997713fe7d38f735b7b7c
https://doi.org/10.1159/000007182
https://doi.org/10.1159/000007182
Autor:
Rajeev Kumar, Surendra N. Pandeya, Ramji Yadav, R. Roy, Hariram Singh, T.S. Sirohi, Anurag Chaudhary
Publikováno v:
Scopus-Elsevier
1,2,4-Triazine nucleus is a prominent structural core system present in numerous pharmacologically active compounds. Till date, various 1,2,4-triazine analogs, possesing a wide range of potent pharmacological activities, have been reported. This revi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5711f17a80e4a3a93a5c6b11edeadb38
https://pubmed.ncbi.nlm.nih.gov/24479860
https://pubmed.ncbi.nlm.nih.gov/24479860
Autor:
U. Pugazhenthi, Jonathan R. Dimmock, Jan Balzarini, G. Y. Kao, J. W. Quail, Erik Declercq, Surendra N. Pandeya, Theresa M. Allen
Publikováno v:
European Journal of Medicinal Chemistry. 30:303-314
Summary A number of aryl alicyclic ketones were converted to their corresponding semicarbazones, thiosemicarbazones and bis-carbohydrazones. Anticonvulsant activity was displayed by most of the compounds in the maximal electroshock (MES) and subcutan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0079d43431e1960177b9e00801a15738
https://doi.org/10.1016/0223-5234(96)88238-9
https://doi.org/10.1016/0223-5234(96)88238-9