Výsledky vyhledávání - "Surender M. Kharbanda"

Abstract 2718: Co-loading of a novel PI3-Kdelta/HDAC6 dual inhibitor and navitoclax into QuatramerTM biodegradable polymeric nanoparticles synergistically inhibit growth of ER+breast cancer

Autor: Surender M. Kharbanda, Sachchidanand Tiwari, Harshdeep Kaur, Anees Mohammad, Priya Gupta, Harpal Singh

Publikováno v: Cancer Research. 83:2718-2718

Progression and metastasis of ER+ breast cancer depends on multiple signaling cascades. The available conventional treatment options have limited efficacy in ER+ breast cancer. Simultaneous targeting and inhibition of multiple pathways in ER+ cancer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cb9853c928134db30921f2955b74fa3e
https://doi.org/10.1158/1538-7445.am2023-2718

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Abstract 5406: Novel quatramer nano-formulation of dual-targeted PI3-Kδ/HDAC6 inhibitor, HSB-510, suppresses growth of triple negative breast cancer

Autor: Sachchidanand Tiwari, Suiyang Liu, Mohammad Anees, Neha Mehrotra, Ashish Thakur, Gregory Tawa, Gurmit Grewal, Richard M. Stone, Surender M. Kharbanda, Harpal Singh

Publikováno v: Cancer Research. 82:5406-5406

Triple negative breast cancer (TNBC) is an aggressive subtype with limited treatment options and a worse clinical outcome as compared with other breast cancer subtypes. Multiple studies have shown that progression of TNBC depends on more than one sig

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::229b6e7367dcc555fffd8fe9796da299
https://doi.org/10.1158/1538-7445.am2022-5406

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