Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Suraj Mukatira"'
Autor:
Suraj Mukatira, David Finkelstein, Ashley Interiano, Ying Yang, R. Sathish Srinivasan, Miriam E. Dillard, Harri Nurmi, Hyea Jin Gil, Noelia Escobedo, Guillermo Oliver, Kari Alitalo
Publikováno v:
Genes & Development. 28:2175-2187
The mammalian lymphatic vasculature is important for returning fluids from the extracellular tissue milieu back to the blood circulation. We showed previously that Prox1 dosage is important for the development of the mammalian lymphatic vasculature.
Autor:
James R. Downing, Kerri Ochoa, Michael Rusch, Jacqueline Flores-Otero, Jinghui Zhang, Anatoly Ulyanov, Jianmin Wang, Stanley Pounds, Sheila A. Shurtleff, Pankaj Gupta, Gang Wu, Justina McEvoy, Xiang Chen, David H. Ellison, Xin Hong, Richard K. Wilson, Li Ding, Amity L. Manning, David J. Dooling, Lucinda Fulton, Geoff Neale, Suraj Mukatira, Charles Lu, Matthew W. Wilson, David Zhao, Nicholas J. Dyson, Armita Bahrami, Elaine R. Mardis, Clayton W. Naeve, John Easton, Robert S. Fulton, Charles G. Mullighan, Michael A. Dyer, Rachel C. Brennan, Jing Ma, Claudia A. Benavente
Publikováno v:
Nature, vol 481, iss 7381
Retinoblastoma is an aggressive childhood cancer of the developing retina that is initiated by the biallelic loss of RB1. Tumours progress very quickly following RB1 inactivation but the underlying mechanism is not known. Here we show that the retino
Autor:
David B. Finkelstein, Perdeep K. Mehta, Robert G. Webster, John C. Obenauer, Clayton W. Naeve, Xiaoping Su, Suraj Mukatira
Publikováno v:
Journal of Virology. 81:10292-10299
Avian influenza viruses have adapted to human hosts, causing pandemics in humans. The key host-specific amino acid mutations required for an avian influenza virus to function in humans are unknown. Through multiple-sequence alignment and statistical
Autor:
Scott Krauss, Yiping Fan, Karen M. Rakestraw, Perdeep K. Mehta, David B. Finkelstein, Clayton W. Naeve, Jing Ma, Jinhua Wang, Xiaoping Su, Jackie Denson, John C. Obenauer, Jie Zheng, Ziwei Zhang, Erich Hoffmann, Suraj Mukatira, Xiequn Xu, Robert G. Webster
Publikováno v:
Science. 311:1576-1580
The spread of H5N1 avian influenza viruses (AIVs) from China to Europe has raised global concern about their potential to infect humans and cause a pandemic. In spite of their substantial threat to human health, remarkably little AIV whole-genome inf
Autor:
Cheng Cheng, J Pfeffer, C H Pui, A Bogni, Wenjian Yang, Mary V. Relling, W Liu, Deborah L. French, Suraj Mukatira, James R. Downing
Publikováno v:
Leukemia. 20:239-246
Using a target gene approach, only a few host genetic risk factors for treatment-related myeloid leukemia (t-ML) have been defined. Gene expression microarrays allow for a more genome-wide approach to assess possible genetic risk factors for t-ML. We
Autor:
Suraj Mukatira, Stephan W. Morris, Umar Akbar, Xiaoping Du, Silva H. Hanissian, Anne Hoffmann, Zorica Janjetovic, Norman N. Iscove, Johann Hitzler, Jon H. Robertson, Kristin M. Hamre, Bin Teng, Yiai Tong
Publikováno v:
Oncogene. 23:3700-3707
Myelodysplasia/acute myeloid leukemia (MDS/AML) is characterized by a t(3;5)(q25.1;q34) chromosomal translocation that forms a fusion gene between nucleophosmin (NPM) and MDS/myeloid leukemia factor 1 (MLF1). We identified a novel protein, MLF1-inter
Autor:
Clayton W. Naeve, Karen M. Rakestraw, Martin U. Kuefer, Susana C. Raimondi, Vandana Chinwalla, Frederick G. Behm, Nancy J. Zeleznik-Le, Suraj Mukatira, Stephan W. Morris
Publikováno v:
Oncogene. 22:1418-1424
Translocations interrupting the mixed lineage leukemia gene (MLL) occur in 7–10% of acute lymphoblastic leukemia (ALL) and 5–6% of acute myeloid leukemia (AML) cases. One of these translocations, t(11;15)(q23;q14), occurs rarely in both ALL and A
Autor:
James R. Downing, Suraj Mukatira, Jennifer Moore, Robert B. Lorsbach, Susan Mathew, Susana C. Raimondi
Publikováno v:
Leukemia. 17:637-641
TET1, a member of a novel protein family, is fused to MLL in acute myeloid leukemia containing the t(10;11)(q22;q23)
Autor:
Suraj Mukatira, Ying Yang, Oleg Lagutin, R. Sathish Srinivasan, Yingdi Wang, Xin Geng, Marianna P.R. Porto, Guillermo Oliver, Michèle Studer
The homeobox gene Prox1 is crucial for mammalian lymphatic vascular development. In the absence of Prox1, lymphatic endothelial cells (LECs) are not specified. The maintenance of LEC identity also requires the constant expression of Prox1. However, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e42c0aed5ba3d2f9fb1deb3a3d6181cd
https://europepmc.org/articles/PMC2849126/
https://europepmc.org/articles/PMC2849126/
Publikováno v:
The 2003 Congress on Evolutionary Computation, 2003. CEC '03..
The paper presents a genetic mining approach to discover highly conserved motifs amongst upstream sequences of co-regulated genes. These motifs represent putative cis-regulatory elements that could play an important role in the co-ordinated expressio