Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Suraj B. Teegala"'
Autor:
Suraj B. Teegala, Pallabi Sarkar, Dashiel M. Siegel, Zhenyu Sheng, Lihong Hao, Nicholas T. Bello, Luis De Lecea, Kevin D. Beck, Vanessa H. Routh
Publikováno v:
Molecular Metabolism, Vol 76, Iss , Pp 101788- (2023)
Objective: The present study tests the hypothesis that changes in the glucose sensitivity of lateral hypothalamus (LH) hypocretin/orexin glucose-inhibited (GI) neurons following weight loss leads to glutamate plasticity on ventral tegmental area (VTA
Externí odkaz:
https://doaj.org/article/3e3e5feead66492db315da933d2eb502
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Hypoglycemia is a profound threat to the brain since glucose is its primary fuel. As a result, glucose sensors are widely located in the central nervous system and periphery. In this perspective we will focus on the role of hypothalamic glucose-inhib
Externí odkaz:
https://doaj.org/article/319a4ec3e36147b59ab4b9b613a73255
Autor:
Vishwendra Patel, Pallabi Sarkar, Dashiel M. Siegel, Suraj B. Teegala, Pamela R. Hirschberg, Hamad Wajid, Omar Itani, Vanessa H. Routh
Publikováno v:
Diabetes.
Perifornical hypothalamus (PFH) orexin glucose-inhibited (GI) neurons that facilitate arousal have been implicated in hypoglycemia awareness. Mice lacking orexin exhibit narcolepsy and orexin mediates the effect of the anti-narcolepsy drug, modafinil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75ac21cdfd53390c036d6459f3cac11a
https://doi.org/10.2337/db22-0639
https://doi.org/10.2337/db22-0639
Autor:
Vanessa H. Routh, Gwyndolin M. Vail, Pallabi Sarkar, Suraj B. Teegala, Dashiel M. Siegel, Pamela R. Hirschberg, Stephanie M. Garcia
Publikováno v:
Journal of Neuroendocrinology. 33
Subsequent to the discovery of insulin 100 years ago, great strides have been made in understanding its function, especially in the brain. It is now clear that insulin is a critical regulator of the neuronal circuitry controlling energy balance and g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88822d6e790b89701a5c1a2efd995c29
https://doi.org/10.1111/jne.12937
https://doi.org/10.1111/jne.12937
Autor:
Vanessa H. Routh, Pamela R. Hirschberg, Stephanie M. Garcia, Dashiel M. Siegel, Pallabi Sarkar, Gwyndolin M. Vail, Suraj B. Teegala
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86eb6704dba48aaf8cd870ef4ff49206
https://doi.org/10.1111/jne.12937/v2/response1
https://doi.org/10.1111/jne.12937/v2/response1
Publikováno v:
Journal of neuroendocrinology. 32(1)
The ventromedial hypothalamus (VMH) plays a complex role in glucose and energy homeostasis. The VMH is necessary for the counter-regulatory response to hypoglycaemia (CRR) that increases hepatic gluconeogenesis to restore euglycaemia. On the other ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9016990442cf42816838eacdc3d3bbb
https://pubmed.ncbi.nlm.nih.gov/31329314
https://pubmed.ncbi.nlm.nih.gov/31329314
Autor:
Zhenyu Sheng, Miloni S. Dalal, Vanessa H. Routh, Suraj B. Teegala, Pamela R. Hirschberg, Kevin D. Beck
Publikováno v:
Brain Res
Glucose inhibits ~60% of lateral hypothalamic (LH) orexin neurons. Fasting increases the activation of LH orexin glucose-inhibited (GI) neurons in low glucose. Increases in spontaneous glutamate excitatory postsynaptic currents (sEPSCs) onto putative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8b3a30fa2750dd1c0afae83a55edf6d
https://pubmed.ncbi.nlm.nih.gov/29787770
https://pubmed.ncbi.nlm.nih.gov/29787770
Publikováno v:
Frontiers in Physiology
Frontiers in Physiology, Vol 9 (2018)
Frontiers in Physiology, Vol 9 (2018)
Hypoglycemia is a profound threat to the brain since glucose is its primary fuel. As a result, glucose sensors are widely located in the central nervous system and periphery. In this perspective we will focus on the role of hypothalamic glucose-inhib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65b039787b6fb5e801e1bafc12c411ec
https://pubmed.ncbi.nlm.nih.gov/29593556
https://pubmed.ncbi.nlm.nih.gov/29593556