Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Suraj B Sable"'
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e113951 (2014)
Mycobacterium bovis bacille Calmette-Guérin (BCG) is the most widely used live attenuated vaccine. However, the correlates of protection and waning of its immunity against tuberculosis is poorly understood. In this study, we correlated the longitudi
Externí odkaz:
https://doaj.org/article/bff73c20e3a44bfcbc667e41adf8b321
Autor:
Subhadra Nandakumar, Sunil Kannanganat, Karen M Dobos, Megan Lucas, John S Spencer, Sunan Fang, Melissa A McDonald, Jan Pohl, Kristin Birkness, Venkateswarlu Chamcha, Melissa V Ramirez, Bonnie B Plikaytis, James E Posey, Rama Rao Amara, Suraj B Sable
Publikováno v:
PLoS Pathogens, Vol 9, Iss 10, p e1003705 (2013)
Glycosylation is the most abundant post-translational polypeptide chain modification in nature. Although carbohydrate modification of protein antigens from many microbial pathogens constitutes important components of B cell epitopes, the role in T ce
Externí odkaz:
https://doaj.org/article/fcf78577f37e4cc6977ecb1867a11d5d
Autor:
Suraj B Sable, Mani Cheruvu, Subhadra Nandakumar, Sunita Sharma, Kakali Bandyopadhyay, Kathryn L Kellar, James E Posey, Bonnie B Plikaytis, Rama Rao Amara, Thomas M Shinnick
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22718 (2011)
BACKGROUND: The identification of Mycobacterium tuberculosis vaccines that elicit a protective immune response in the lungs is important for the development of an effective vaccine against tuberculosis. METHODS AND PRINCIPAL FINDINGS: In this study,
Externí odkaz:
https://doaj.org/article/6e29d37e692a44a4b165617b0b79b2b9
Publikováno v:
Clin Microbiol Rev
Tuberculosis (TB) is the leading killer among all infectious diseases worldwide despite extensive use of the Mycobacterium bovis bacille Calmette-Guerin (BCG) vaccine. A safer and more effective vaccine than BCG is urgently required. More than a doze
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cb51f72fe589622380079b0ade56631
https://pubmed.ncbi.nlm.nih.gov/31666281
https://pubmed.ncbi.nlm.nih.gov/31666281
Autor:
Karen M. Dobos, Sunil Kannanganat, John S. Spencer, Bonnie B. Plikaytis, Megan Lucas, Subhadra Nandakumar, Rama Rao Amara, Suraj B. Sable, James E. Posey
Publikováno v:
Scientific Reports
Heterologous prime–boosting has emerged as a powerful vaccination approach against tuberculosis. However, optimal timing to boost BCG-immunity using subunit vaccines remains unclear in clinical trials. Here, we followed the adhesin Apa-specific T-c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49b91bbe530e00fa309511cc6bc38b4e
https://doi.org/10.1038/srep25837
https://doi.org/10.1038/srep25837
Autor:
Larry S. Schlesinger, Suraj B. Sable, Rama Rao Amara, Vijayakumar Velu, Fatoumata B. Sow, Thomas M. Shinnick, Subhadra Nandakumar, Kathryn L. Kellar, William P. Lafuse
Publikováno v:
Tuberculosis. 91:314-321
Summary We investigated the in vitro production of the antimicrobial peptide hepcidin by cells of the innate immune system that harbor Mycobacterium tuberculosis . Stimulation of mouse lung macrophages with M. tuberculosis or IFN-γ + M. tuberculosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::092838a01909d897bf3b0679756a59a0
https://doi.org/10.1016/j.tube.2011.03.003
https://doi.org/10.1016/j.tube.2011.03.003
Autor:
Suraj B. Sable, James E. Posey, Jeong Woo Lee, Mark R. Prausnitz, Yeu-Chun Kim, Seong-O Choi, Yasuhiro Hiraishi, Subhadra Nandakumar
Publikováno v:
Vaccine. 29:2626-2636
Tuberculosis (TB) caused by Mycobacterium tuberculosis continues to be a leading cause of mortality among bacterial diseases, and the bacillus Calmette-Guerin (BCG) is the only licensed vaccine for human use against this disease. TB prevention and co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3506ee537f18e956449ad969f561ff47
https://doi.org/10.1016/j.vaccine.2011.01.042
https://doi.org/10.1016/j.vaccine.2011.01.042
Autor:
Neena Mehta, Suraj B. Sable, Digambar Behera, Pawan Sharma, Jaspreet Singh, Jaspreet Kaur, Indu Verma, Gopal K. Khuller, Ajay Grover, Mamta Kalra
Publikováno v:
Clinical Immunology. 125:173-183
Different combinations of ESAT-6, CFP-10, CFP-21, MPT-64, encoded by RD1 and RD2 of Mycobacterium tuberculosis were evaluated on the basis of antigenicity in PPD positive TB contacts and immunogenicity in C57BL/6J mice immunized with the combination
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e10d0cec244a49c7fb4d62e844f76ac8
https://doi.org/10.1016/j.clim.2007.07.007
https://doi.org/10.1016/j.clim.2007.07.007
Publikováno v:
Clinical Immunology. 122:239-251
The attempts to find an effective antituberculous subunit vaccine are based on the assumption that it must drive a Th1 response. In the absence of effective correlates of protection, a vast array of mycobacterial components are being evaluated worldw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4325460f3bd5136661ce50d34f83a1cc
https://doi.org/10.1016/j.clim.2006.10.010
https://doi.org/10.1016/j.clim.2006.10.010
Publikováno v:
Vaccine. 25:1553-1566
Tuberculosis caused by Mycobacterium tuberculosis continues to be one of the major public health problems in the world. The eventual control of this disease will require the development of a safe and effective vaccine. One of the approaches receiving
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86c55dcb5cddaa38ab436a519bf40800
https://doi.org/10.1016/j.vaccine.2006.11.014
https://doi.org/10.1016/j.vaccine.2006.11.014