Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Surachet, Imlimthan"'
Autor:
Jelena Matović, Juulia Järvinen, Iris K. Sokka, Surachet Imlimthan, Olli Aitio, Mirkka Sarparanta, Jarkko Rautio, Filip S. Ekholm
Publikováno v:
Molecules, Vol 29, Iss 17, p 4263 (2024)
Boron Neutron Capture Therapy (BNCT) is a cancer treatment which combines tumor-selective boron delivery agents with thermal neutrons in order to selectively eradicate cancer cells. In this work, we focus on the early-stage development of carbohydrat
Externí odkaz:
https://doaj.org/article/9c47b19bd5b341ce9b2e8aff4ce2ab60
Autor:
Tilman Läppchen, Adrianna Bilinska, Eirinaios Pilatis, Elena Menéndez, Surachet Imlimthan, Euy Sung Moon, Ali Afshar-Oromieh, Frank Rösch, Axel Rominger, Eleni Gourni
Publikováno v:
Molecules, Vol 29, Iss 13, p 3093 (2024)
Background: FAP radiopharmaceuticals show promise for cancer diagnosis; however, their limited tumor residency hinders treatment. This study compared two FAPi derivatives, DOTA.SA.FAPi and DOTAGA.(SA.FAPi)2, labeled with gallium-68 and lutetium-177,
Externí odkaz:
https://doaj.org/article/285d4217cb994469b1b11d23d67b90fa
Autor:
Surachet Imlimthan, Euy Sung Moon, Hendrik Rathke, Ali Afshar-Oromieh, Frank Rösch, Axel Rominger, Eleni Gourni
Publikováno v:
Pharmaceuticals, Vol 14, Iss 10, p 1023 (2021)
Over the past decade, the tumor microenvironment (TME) has become a new paradigm of cancer diagnosis and therapy due to its unique biological features, mainly the interconnection between cancer and stromal cells. Within the TME, cancer-associated fib
Externí odkaz:
https://doaj.org/article/c92b212da1a04611a9f34e3bc1ee26ea
Autor:
Elisavet Lambidis, Dave Lumén, Elina Koskipahta, Surachet Imlimthan, Brianda B. Lopez, Ana Isabel Fraguas Sánchez, Mirkka Sarparanta, R. Holland Cheng, Anu J. Airaksinen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::062fff7657fa3ba3192b47cb006b90b0
http://hdl.handle.net/10138/356061
http://hdl.handle.net/10138/356061
Autor:
Sofia Otaru, Surachet Imlimthan, Mirkka Sarparanta, Kerttuli Helariutta, Kristiina Wähälä, Anu J. Airaksinen
Publikováno v:
Molecules, Vol 25, Iss 5, p 1208 (2020)
Fluorine-18 is the most widely used positron emission tomography (PET) radionuclide currently in clinical application, due to its optimal nuclear properties. The synthesis of 18F-labeled radiotracers often requires harsh reaction conditions, limiting
Externí odkaz:
https://doaj.org/article/3761c67f6f47490b89366babef7a14ef
Autor:
Mirkka Sarparanta, Surachet Imlimthan, Iris Katariina Sokka, Filip S. Ekholm, Mikael P. Johansson, Hannu Maaheimo
Publikováno v:
Sokka, I K, Imlimthan, S, Sarparanta, M, Maaheimo, H, Johansson, M P & Ekholm, F S 2021, ' Halogenation at the phenylalanine residue of monomethyl auristatin f leads to a favorable cis/ trans equilibrium and retained cytotoxicity ', Molecular Pharmaceutics, vol. 18, no. 8, pp. 3125-3131 . https://doi.org/10.1021/acs.molpharmaceut.1c00342
Molecular Pharmaceutics
Molecular Pharmaceutics
Halogenation can be utilized for the purposes of labeling and molecular imaging, providing a means to, e.g., follow drug distribution in an organism through positron emission tomography (PET) or study the molecular recognition events unfolding by nuc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d95f58ef077c9074a6334b247722d50d
https://doi.org/10.1021/acs.molpharmaceut.1c00342
https://doi.org/10.1021/acs.molpharmaceut.1c00342
Autor:
Jelena Matović, Juulia Järvinen, Iris K. Sokka, Philipp Stockmann, Martin Kellert, Surachet Imlimthan, Mirkka Sarparanta, Mikael P. Johansson, Evamarie Hey-Hawkins, Jarkko Rautio, Filip S. Ekholm
Glucose-and sodium-dependent glucose transporters (GLUTs and SGLTs) play vital roles in human biology. Of the 14 GLUTs and 12 SGLTs, the GLUT1 transporter has gained t h e most widespread recognition because GLUT1 is overexpressed in several cancers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f817c06505986eb7aff16321321477a
http://hdl.handle.net/10138/350550
http://hdl.handle.net/10138/350550
Autor:
Elisavet Lambidis, Chun-Chieh Chen, Mo Baikoghli, Surachet Imlimthan, You Cheng Khng, Mirkka Sarparanta, R. Holland Cheng, Anu J. Airaksinen
Publikováno v:
Molecular pharmaceutics, vol 19, iss 8
Targeted delivery of diagnostics and therapeutics offers essential advantages over nontargeted systemic delivery. These include the reduction of toxicity, the ability to reach sites beyond biological barriers, and the delivery of higher cargo concent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ec029a75cf9f769673d985d0572f142
https://escholarship.org/uc/item/0p13w9sh
https://escholarship.org/uc/item/0p13w9sh
Autor:
Elisavet, Lambidis, Chun-Chieh, Chen, Mo, Baikoghli, Surachet, Imlimthan, You Cheng, Khng, Mirkka, Sarparanta, R Holland, Cheng, Anu J, Airaksinen
Publikováno v:
Molecular pharmaceutics. 19(8)
Targeted delivery of diagnostics and therapeutics offers essential advantages over nontargeted systemic delivery. These include the reduction of toxicity, the ability to reach sites beyond biological barriers, and the delivery of higher cargo concent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ab6ff829a5444742b7cccc2d294d7586
https://pubmed.ncbi.nlm.nih.gov/35857429
https://pubmed.ncbi.nlm.nih.gov/35857429
Autor:
Sofia Otaru, Andreas Paulus, Surachet Imlimthan, Iida Kuurne, Helena Virtanen, Heidi Liljenbäck, Tuula Tolvanen, Tatsiana Auchynnikava, Anne Roivainen, Kerttuli Helariutta, Mirkka Sarparanta, Anu J. Airaksinen
Radiolabeled peptides have emerged as highly specific agents for targeting receptors expressed in tumors for therapeutic and diagnostic purposes. Peptides developed for positron emission tomography (PET) are typically radiolabeled using prosthetic gr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38ea03a5f333a8fa1eacb5931a96b6c6
http://hdl.handle.net/10138/347098
http://hdl.handle.net/10138/347098