Estrogen receptor activation reduces lipid synthesis in pancreatic islets and prevents β cell failure in rodent models of type 2 diabetes

Autor: Franck Mauvais-Jarvis, Meenakshi Kaw, Cédric Le May, Saja S. Khuder, Sonia M. Najjar, Kenneth S. Korach, Martin G. Latour, Viviane Delghingaro-Augusto, Marc Prentki, Suhuan Liu, Surabhi A. Bhatt, Joseph P. Tiano

Publikováno v: Journal of Clinical Investigation
Journal of Clinical Investigation, American Society for Clinical Investigation, 2011, 121 (8), pp.3331-3342. ⟨10.1172/JCI44564⟩

The failure of pancreatic β cells to adapt to an increasing demand for insulin is the major mechanism by which patients progress from insulin resistance to type 2 diabetes (T2D) and is thought to be related to dysfunctional lipid homeostasis within

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed6417ca53b022651a13e772cc625af5
https://doi.org/10.1172/jci44564