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Akademický článek

Experimental Carbonic Anhydrase Inhibitors for the Treatment of Hypoxic Tumors

Autor: Supuran CT

Publikováno v: Journal of Experimental Pharmacology, Vol Volume 12, Pp 603-617 (2020)

Claudiu T Supuran Neurofarba Department, Pharmaceutical and Nutraceutical Section, University of Florence, Florence 50019, ItalyCorrespondence: Claudiu T SupuranNeurofarba Department, Pharmaceutical and Nutraceutical Section, University of Florence,

Externí odkaz: https://doaj.org/article/a3a92275d97e478ebd9ad6ee019aec58

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Novel Indole-Based Hydrazones as Potent Inhibitors of the α-class Carbonic Anhydrase from Pathogenic Bacterium Vibrio cholerae

Autor: Demir-Yazıcı, K, Güzel-Akdemir, Ö, Angeli, A, Supuran, Ct, Akdemir, Atilla

Due to the increasing resistance of currently used antimicrobial drugs, there is an urgent problem for the treatment of cholera disease, selective inhibition of the α-class carbonic anhydrases (CA, EC 4.2.1.1) from the pathogenic bacterium Vibrio ch

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______9651::2c0d52848a0cc893d5d1930871cf3f2c
https://hdl.handle.net/20.500.12645/17995

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Activation studies of the ?-carbonic anhydrases from Malassezia restricta with amines and amino acids' in 'Activation studies of the beta-carbonic anhydrases from Malassezia restricta with amines and amino acids'

Autor: Angeli A, Prete SD, Ghobril C, Hitce J, Clavaud C, Marrat X, Donald WA, Capasso C, Supuran CT

Publikováno v: Journal of enzyme inhibition and medicinal chemistry (Online) (2020). doi:10.1080/14756366.2020.1743284
info:cnr-pdr/source/autori:Angeli A, Prete SD, Ghobril C, Hitce J, Clavaud C, Marrat X, Donald WA, Capasso C, Supuran CT/titolo:Activation studies of the ?-carbonic anhydrases from Malassezia restricta with amines and amino acids" in "Activation studies of the beta-carbonic anhydrases from Malassezia restricta with amines and amino acids"/doi:10.1080%2F14756366.2020.1743284/rivista:Journal of enzyme inhibition and medicinal chemistry (Online)/anno:2020/pagina_da:/pagina_a:/intervallo_pagine:/volume

The ?- and ?-class carbonic anhydrases (CAs, EC 4.2.1.1) from the pathogenic bacterium Vibrio cholerae, VchCA?, and VchCA?, were investigated for their activation with natural and non-natural amino acids and amines. The most effective VchCA? activato

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=cnr_________::992c38f15db72b6246e5cec0958df8e1
https://publications.cnr.it/doc/419058

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Identification and characterization of the a-CA in the outer membrane vesicles produced by Helicobacter pylori

Autor: Ronci M, Del Prete S, Puca V, Carradori S, Carginale V, Muraro R, Mincione G, Aceto A, Sisto F, Supuran CT, Grande R, Capasso C.

Publikováno v: Journal of enzyme inhibition and medicinal chemistry (Online) (2019). doi:10.1080/14756366.2018.1539716.
info:cnr-pdr/source/autori:Ronci M, Del Prete S, Puca V, Carradori S, Carginale V, Muraro R, Mincione G, Aceto A, Sisto F, Supuran CT, Grande R, Capasso C./titolo:Identification and characterization of the a-CA in the outer membrane vesicles produced by Helicobacter pylori/doi:10.1080%2F14756366.2018.1539716./rivista:Journal of enzyme inhibition and medicinal chemistry (Online)/anno:2019/pagina_da:/pagina_a:/intervallo_pagine:/volume

The genome of Helicobacter pylori encodes for carbonic anhydrases (CAs, EC 4.2.1.1) belonging to the ?- and ?-CA classes, which together with urease, have a pivotal role in the acid acclimation of the microorganism within the human stomach. Recently,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=cnr_________::97982054a8c6cb04ea08f6915b40a148
http://www.cnr.it/prodotto/i/406214

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BRAIN CARBONIC ANHYDRASES INHIBITION IMPAIRS FEAR MEMORY EXTINCTION IN RATS

Autor: Provensi, G, Schmidt, Sd, Rani, B, Costa, A, Carta, F, de Carvalho Myskiw, J., Passani, Mb, Izquierdo, I, Supuran, Ct, Blandina, P

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______310::8ae5bb6b4892aadd0294d45deea55e91
http://hdl.handle.net/2158/1135475

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Characterization of carbonic anhydrase in interactome reveals proteins assisting its nuclear localization in hypoxic cells

Autor: Buanne P, Renzone G, Monteleone F, Vitale M, Monti SM, Sandomenico A, Garbi C, Montanaro D, Troncone G, Zaticova M, Csaderova L, Supuran CT, Pastorekova S, Scaloni A, De Simone G, zambrano N., ACCARDO, Marina

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3977::1837cc2475cce10722a603d5693832ed
http://hdl.handle.net/11591/217027

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Crystal structure of human carbonic anhydrase XIII and its complex with the inhibitor acetazolamide

Autor: Di Fiore A, Monti SM, Hilvo M, Parkkila S, Romano V, Scaloni A, Scozzafava A, Supuran CT, De Simone G., PEDONE, CARLO

The cytosolic isoform XIII is a recently discovered member of the human carbonic anhydrase (hCA, EC 4.2.1.1) family. It is selectively expressed among other tissues in the reproductive organs, where it may control pH and ion balance regulation, ensur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3730::ab6bfd8f725efe138f3a4fdccca48d33
http://hdl.handle.net/11588/348329

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An overview of the alpha-, beta- and gamma-carbonic anhydrases from Bacteria: can bacterial carbonic anhydrases shed new light on evolution of bacteria?

Autor: Capasso C, Supuran CT

Publikováno v: Journal of enzyme inhibition and medicinal chemistry
(2014).
info:cnr-pdr/source/autori:Capasso C, Supuran CT/titolo:An overview of the alpha-, beta-and gamma-carbonic anhydrases from Bacteria: can bacterial carbonic anhydrases shed new light on evolution of bacteria?/doi:/rivista:Journal of enzyme inhibition and medicinal chemistry (Print)/anno:2014/pagina_da:/pagina_a:/intervallo_pagine:/volume

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=cnr_________::b89d3f30f6b462524307fd47c331222b
https://publications.cnr.it/doc/285507

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Biochemical characterization of the delta-carbonic anhydrase from the marine diatom Thalassiosira weissflogii, TweCA

Autor: Del Prete S, Vullo D, De Luca V, Supuran CT, Capasso C.

Publikováno v: Journal of enzyme inhibition and medicinal chemistry
(2014).
info:cnr-pdr/source/autori:Del Prete S, Vullo D, De Luca V, Supuran CT, Capasso C./titolo:Biochemical characterization of the delta-carbonic anhydrase from the marine diatom Thalassiosira weissflogii, TweCA/doi:/rivista:Journal of enzyme inhibition and medicinal chemistry (Print)/anno:2014/pagina_da:/pagina_a:/intervallo_pagine:/volume

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=cnr_________::621179656db119be882adacede985b50
https://publications.cnr.it/doc/285500

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Biochemical characterization of recombinant beta-carbonic anhydrase (PgiCAb) identified in the genome of the oral pathogenic bacterium Porphyromonas gingivalis

Autor: Del Prete S, Vullo D, De Luca V, AlOthman Z, Osman SM, Supuran CT, Capasso C.

Publikováno v: Journal of enzyme inhibition and medicinal chemistry
(2014).
info:cnr-pdr/source/autori:Del Prete S, Vullo D, De Luca V, AlOthman Z, Osman SM, Supuran CT, Capasso C./titolo:Biochemical characterization of recombinant beta-carbonic anhydrase (PgiCAb) identified in the genome of the oral pathogenic bacterium Porphyromonas gingivalis./doi:/rivista:Journal of enzyme inhibition and medicinal chemistry (Print)/anno:2014/pagina_da:/pagina_a:/intervallo_pagine:/volume

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=cnr_________::4d3998cf990901121e7dc22417fae5ba
https://publications.cnr.it/doc/285501

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