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Akademický článek

Virtual Screening of Alkaloid and Terpenoid Inhibitors of SMT Expressed in Naegleria sp.

Autor: Jason Abraham, Neha Chauhan, Supriyo Ray

Publikováno v: Molecules, Vol 27, Iss 17, p 5727 (2022)

The pathogenic form of thermophilic Naegleria sp. i.e., Naegleria fowleri, also known as brain eating amoeba, causes primary amoebic encephalitis (PAM) with a >97% fatality rate. To date, there are no specific drugs identified to treat this disease s

Externí odkaz: https://doaj.org/article/b727cea926224e13a7f5ac1318c947d3

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Akademický článek

Synthetic, Photosynthetic, and Chemical Strategies to Enhance Carbon Dioxide Fixation

Autor: Supriyo Ray, Jason Abraham, Nyiah Jordan, Mical Lindsay, Neha Chauhan

Publikováno v: C, Vol 8, Iss 1, p 18 (2022)

The present human population is more than three times what it was in 1950. With that, there is an increasing demand for the consumption of fossil fuels for various anthropogenic activities. This consumption is the major source of carbon dioxide emiss

Externí odkaz: https://doaj.org/article/5ea1648d219247d585ec29129ada91eb

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Akademický článek

Development of an In Vitro Membrane Model to Study the Function of EsxAB Heterodimer and Establish the Role of EsxB in Membrane Permeabilizing Activity of Mycobacterium tuberculosis

Autor: Salvador Vazquez Reyes, Supriyo Ray, Javier Aguilera, Jianjun Sun

Publikováno v: Pathogens, Vol 9, Iss 12, p 1015 (2020)

EsxA and EsxB are secreted as a heterodimer and have been shown to play critical roles in phagosome rupture and translocation of Mycobacterium tuberculosis into the cytosol. Recent in vitro studies have suggested that the EsxAB heterodimer is dissoci

Externí odkaz: https://doaj.org/article/89fc558222a642a38a831321366aa59b

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Akademický článek

Neurotransmitter Specific, Cellular-Resolution Functional Brain Mapping Using Receptor Coated Nanoparticles: Assessment of the Possibility.

Autor: Ebrahim Forati, Abas Sabouni, Supriyo Ray, Brian Head, Christian Schoen, Dan Sievenpiper

Publikováno v: PLoS ONE, Vol 10, Iss 12, p e0145852 (2015)

Receptor coated resonant nanoparticles and quantum dots are proposed to provide a cellular-level resolution image of neural activities inside the brain. The functionalized nanoparticles and quantum dots in this approach will selectively bind to diffe

Externí odkaz: https://doaj.org/article/df86215e1dcb44eb8a03790ee377fc24

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Akademický článek

Substrate-induced unfolding of protein disulfide isomerase displaces the cholera toxin A1 subunit from its holotoxin.

Autor: Michael Taylor, Helen Burress, Tuhina Banerjee, Supriyo Ray, David Curtis, Suren A Tatulian, Ken Teter

Publikováno v: PLoS Pathogens, Vol 10, Iss 2, p e1003925 (2014)

To generate a cytopathic effect, the catalytic A1 subunit of cholera toxin (CT) must be separated from the rest of the toxin. Protein disulfide isomerase (PDI) is thought to mediate CT disassembly by acting as a redox-driven chaperone that actively u

Externí odkaz: https://doaj.org/article/635581e0a8714f3580cebb72c43a5663

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Akademický článek

Grape extracts inhibit multiple events in the cell biology of cholera intoxication.

Autor: Srikar Reddy, Michael Taylor, Mojun Zhao, Patrick Cherubin, Sandra Geden, Supriyo Ray, David Francis, Ken Teter

Publikováno v: PLoS ONE, Vol 8, Iss 9, p e73390 (2013)

Vibrio cholerae produces cholera toxin (CT), an AB5 protein toxin that is primarily responsible for the profuse watery diarrhea of cholera. CT is secreted into the extracellular milieu, but the toxin attacks its Gsα target within the cytosol of a ho

Externí odkaz: https://doaj.org/article/589855db24614226a75aa9bdc1d8ef87

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Akademický článek

Modulation of toxin stability by 4-phenylbutyric acid and negatively charged phospholipids.

Autor: Supriyo Ray, Michael Taylor, Mansfield Burlingame, Suren A Tatulian, Ken Teter

Publikováno v: PLoS ONE, Vol 6, Iss 8, p e23692 (2011)

AB toxins such as ricin and cholera toxin (CT) consist of an enzymatic A domain and a receptor-binding B domain. After endocytosis of the surface-bound toxin, both ricin and CT are transported by vesicle carriers to the endoplasmic reticulum (ER). Th

Externí odkaz: https://doaj.org/article/669231b3f8074b73bff052cd952f0df3

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Co-sputtered Antibacterial and Biocompatible Nanocomposite Titania-Zinc Oxide thin films on Si substrates for Dental Implant applications

Autor: R. Jayaganthan, Supriyo Ray, P. Dubey, Shreya Goel, Ramesh Chandra, Aditya Bhusan Pant

Publikováno v: Materials Technology. 34:32-42

The present work explores the possible applications of co-sputtered titania(Ti)-zinc(Zn)-oxide nanocomposite-(nC) thin films to improve the bonding of metallic fixture with bone. As a proof of principle study, the nC-titania-zinc-oxide thin films hav

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::29f93e5fcab1e69db445c8c52a2f65ba
https://doi.org/10.1080/10667857.2018.1488924

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Deletion of caveolin scaffolding domain alters cancer cell migration

Autor: Aayush Boddu, Yousuke T. Horikawa, Jonathan Okerblom, Sunaho Okada, Sadaf Azad Raja, Fiona Murray, Hideshi Okada, Itta Kawamura, Supriyo Ray, Yoshiteru Murofushi, Hemal H. Patel

Publikováno v: Cell Cycle

Caveolin-1 (Cav-1) is an integral membrane protein that plays an important role in proliferative and terminally differentiated cells. As a structural component of Caveolae, Cav-1 interacts with signaling molecules via a caveolin scaffolding domain (C

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ce4518b0773b4a751b34386865ee766
https://pubmed.ncbi.nlm.nih.gov/31116089

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