Zobrazeno 1 - 2
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pro vyhledávání: '"Supriya V. Gaitonde"'
Publikováno v:
Carcinogenesis. 22:957-964
Bile acids, principally deoxycholic acid (DCA), have been implicated in the promotion of colon tumorigenesis in both animals and humans. Increasing evidence suggests that bile acids may exert their tumor promoting activity by modulating intracellular
Publikováno v:
Oncogene. 19:4042-4049
P53 is inactivated in tumors by mechanisms other than mutations in the p53 gene itself. To gain insight into the mechanisms by which this inactivation occurs, we chemically mutagenized A1-5 cells expressing high levels of temperature sensitive p53val