Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Supriya Srinivasan"'
Autor:
Chung-Chih Liu, Ayub Khan, Nicolas Seban, Nicole Littlejohn, Aayushi Shah, Supriya Srinivasan
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract In C. elegans mechanisms by which peripheral organs relay internal state information to the nervous system remain unknown, although strong evidence suggests that such signals do exist. Here we report the discovery of a peptide of the ancestr
Externí odkaz:
https://doaj.org/article/afe4309e689c4935b4b944910d3258c5
Autor:
Supriya Srinivasan
Publikováno v:
eLife, Vol 10 (2021)
Making choices about food affects the metabolism and lifespan of fruit flies.
Externí odkaz:
https://doaj.org/article/0a334bee11394e32ad7fa968f3bd838a
Publikováno v:
eLife, Vol 9 (2020)
The relationship between lipid metabolism and longevity remains unclear. Although fat oxidation is essential for weight loss, whether it remains beneficial when sustained for long periods, and the extent to which it may attenuate or augment lifespan
Externí odkaz:
https://doaj.org/article/877867efdcda47e99bf2a3c8b7c3d972
Autor:
Bernard P. Kok, Andrea Galmozzi, Nicole K. Littlejohn, Verena Albert, Cristina Godio, Woojoo Kim, Sean M. Kim, Jeffrey S. Bland, Neile Grayson, Mingliang Fang, Wolfgang Meyerhof, Gary Siuzdak, Supriya Srinivasan, Maik Behrens, Enrique Saez
Publikováno v:
Molecular Metabolism, Vol 16, Iss , Pp 76-87 (2018)
Objectives: Extracts of the hops plant have been shown to reduce weight and insulin resistance in rodents and humans, but elucidation of the mechanisms responsible for these benefits has been hindered by the use of heterogeneous hops-derived mixtures
Externí odkaz:
https://doaj.org/article/13cb3da1ba1b47f5b449b4d9690f02b2
Autor:
Aude D Bouagnon, Lin Lin, Shubhi Srivastava, Chung-Chih Liu, Oishika Panda, Frank C Schroeder, Supriya Srinivasan, Kaveh Ashrafi
Publikováno v:
PLoS Biology, Vol 17, Iss 12, p e3000242 (2019)
The ability to coordinate behavioral responses with metabolic status is fundamental to the maintenance of energy homeostasis. In numerous species including Caenorhabditis elegans and mammals, neural serotonin signaling regulates a range of food-relat
Externí odkaz:
https://doaj.org/article/d8903361c0df4454997764a6cd0684c9
Autor:
Lavinia Palamiuc, Tallie Noble, Emily Witham, Harkaranveer Ratanpal, Megan Vaughan, Supriya Srinivasan
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Serotonin is a potent stimulator of fat loss and energy expenditure in several species, includingC. elegans. Here, Palamiuc et al. identify the neuropeptide, FP-7, and its receptor in the intestine, NRP-22 as mediators of serotonergic body fat loss i
Externí odkaz:
https://doaj.org/article/6730459c83d44b3b82d15e60b1cc4677
Autor:
Rosalind Hussey, Nicole K Littlejohn, Emily Witham, Erik Vanstrum, Jaleh Mesgarzadeh, Harkaranveer Ratanpal, Supriya Srinivasan
Publikováno v:
PLoS Genetics, Vol 14, Iss 3, p e1007305 (2018)
The mechanisms by which the sensory environment influences metabolic homeostasis remains poorly understood. In this report, we show that oxygen, a potent environmental signal, is an important regulator of whole body lipid metabolism. C. elegans oxyge
Externí odkaz:
https://doaj.org/article/9e2216e2b95b40b8ad237f780129a9c8
Autor:
Rosalind Hussey, Jon Stieglitz, Jaleh Mesgarzadeh, Tiffany T Locke, Ying K Zhang, Frank C Schroeder, Supriya Srinivasan
Publikováno v:
PLoS Genetics, Vol 13, Iss 5, p e1006806 (2017)
It is now established that the central nervous system plays an important role in regulating whole body metabolism and energy balance. However, the extent to which sensory systems relay environmental information to modulate metabolic events in periphe
Externí odkaz:
https://doaj.org/article/deb18dd8de53439c93d1d5b5ab9440e3
Publikováno v:
PLoS Biology, Vol 9, Iss 12, p e1001219 (2011)
Bardet-Biedl syndrome, BBS, is a rare autosomal recessive disorder with clinical presentations including polydactyly, retinopathy, hyperphagia, obesity, short stature, cognitive impairment, and developmental delays. Disruptions of BBS proteins in a v
Externí odkaz:
https://doaj.org/article/c9223a293a194ff4a3ecb7521ce7c698
Publikováno v:
PLoS ONE, Vol 2, Iss 7, p e668 (2007)
The molecular and functional diversity of G protein-coupled receptors is essential to many physiological processes. However, this diversity presents a significant challenge to understanding the G protein-mediated signaling events that underlie a spec
Externí odkaz:
https://doaj.org/article/651effe1cb9b418da36ada77c626fdf2