Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Supriya Pai"'
Autor:
Samantha E Wilner, Brian Wengerter, Keith Maier, Maria de Lourdes Borba Magalhães, David Soriano Del Amo, Supriya Pai, Felipe Opazo, Silvio O Rizzoli, Amy Yan, Matthew Levy
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 1, Iss C (2012)
The transferrin receptor, CD71, is an attractive target for drug development because of its high expression on a number of cancer cell lines and the blood brain barrier. To generate serum-stabilized aptamers that recognize the human transferrin recep
Externí odkaz:
https://doaj.org/article/f49eee81e2054e35bc941fe8c69cbbd6
Autor:
Kapaettu Satyamoorthy, Manoj K. Bhat, Manjunath B. Joshi, Aswath Balakrishnan, Supriya Pai, Podila Satya Venkata Narasimha Sharma, Ananthapadmanabha Kotambail
Publikováno v:
Psychiatry research. 273
Bipolar disorder (BD) is multifactorial mood disorder characterized by alternating episodes of hyperactive mania and severe depression. Lithium is one of the most preferred drug used as mood stabilizer in treating BD. In this study, we examined the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8805b74589c44f9c1d82a528668af28
https://pubmed.ncbi.nlm.nih.gov/30658210
https://pubmed.ncbi.nlm.nih.gov/30658210
Publikováno v:
Bioremediation Journal. 17:79-85
The objective of the present study is to investigate the caffeine-degrading abilities of different fungi and to apply this knowledge to environmental remediation and industrial decaffeination process. Chrysosporium keratinophilum, Gliocladium roseum,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::adfa11c7413d65368e4d87c16a2e92fd
https://doi.org/10.1080/10889868.2012.751960
https://doi.org/10.1080/10889868.2012.751960
Autor:
Supriya Pai, Alena M Calm, Heather Welsh, Candice Warner, Christien Kluwe, James Carney, Aroop Sircar, R. E. Hughes, Vlad Codrea, Jianqing Xu, Aleksandr E. Miklos, Patricia E. Buckley, Brian Kuhlman, Monica Berrondo, Andrew D. Ellington, George Georgiou, Bryan S. Der, Jeffrey J. Gray, Melody Zacharko
Publikováno v:
Chemistry & Biology. 19(4):449-455
Summary Mutation of surface residues to charged amino acids increases resistance to aggregation and can enable reversible unfolding. We have developed a protocol using the Rosetta computational design package that "supercharges" proteins while consid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2b8755377c997ee93da22b3947ba0c8
Publikováno v:
Nature Reviews. Drug Discovery
Key Points Aptamers are single-stranded oligonucleotides that fold into defined architectures and bind to targets such as proteins.In binding proteins they often inhibit protein–protein interactions and thereby may elicit therapeutic effects such a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68450413a61d103c78bd0e38ff70900a
https://doi.org/10.1038/nrd3141
https://doi.org/10.1038/nrd3141
Publikováno v:
Expert opinion on medical diagnostics. 2(12)
Aptamers are selected nucleic acids that bind their targets with affinities and specificities that are often comparable to those of monoclonal antibodies.Although aptamers have been adapted to a wide variety of assay formats, the fact that they are n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6021290b7d9781ce03a305a01f646c04
https://pubmed.ncbi.nlm.nih.gov/23496781
https://pubmed.ncbi.nlm.nih.gov/23496781
Autor:
Andrew D. Ellington, Supriya Pai
Publikováno v:
Biosensors and Biodetection ISBN: 9781603275682
The detection and typing of tumor cells based on differentially or similarly expressed antigens (biomarkers) have proven to be increasingly important for the diagnosis and treatment of various cancers. Sensitive techniques for the detection of cell s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59eb9b33bc67f252405f1bf62f77cb24
https://doi.org/10.1007/978-1-60327-569-9_21
https://doi.org/10.1007/978-1-60327-569-9_21
Autor:
Keith E. Maier, Matthew Levy, Amy Yan, Felipe Opazo, David Soriano del Amo, Silvio O. Rizzoli, Samantha E. Wilner, Maria de Lourdes Borba Magalhães, Brian Wengerter, Supriya Pai
Publikováno v:
Molecular Therapy. Nucleic Acids
Molecular Therapy: Nucleic Acids, Vol 1, Iss C (2012)
Molecular Therapy: Nucleic Acids, Vol 1, Iss C (2012)
The transferrin receptor, CD71, is an attractive target for drug development because of its high expression on a number of cancer cell lines and the blood brain barrier. To generate serum-stabilized aptamers that recognize the human transferrin recep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd6ede6a3fc1bf72423a98fb0e335f85
https://doi.org/10.1038/mtna.2012.14
https://doi.org/10.1038/mtna.2012.14
Publikováno v:
Nature Reviews Drug Discovery. 9:660-660
Nature Reviews Drug Discovery 9, 537–550 (2010) The address provided for Anthony D. Keefe was incorrect. The correct address is: X-Chem Incorporated, 100 Beaver Street, Waltham, Massachusetts 02453, USA.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6651f0c96d515105696de23b6c6f7251
https://doi.org/10.1038/nrd3249
https://doi.org/10.1038/nrd3249
Publikováno v:
Nucleic Acids Research
The proximity ligation assay (PLA) has previously been used for the sensitive and specific detection of single proteins. In order to adapt PLA methods for the detection of cell surfaces, we have generated multivalent peptide–oligonucleotide–phyco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b7124aded74d7e763904bac3ce40330
http://europepmc.org/articles/PMC1258177
http://europepmc.org/articles/PMC1258177