Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Supriya G. Prasanth"'
Publikováno v:
Biology, Vol 13, Iss 3, p 152 (2024)
In all eukaryotes, the initiation of DNA replication requires a stepwise assembly of factors onto the origins of DNA replication. This is pioneered by the Origin Recognition Complex, which recruits Cdc6. Together, they bring Cdt1, which shepherds MCM
Externí odkaz:
https://doaj.org/article/207e7829b2934a53a3e904c19a0055c3
Autor:
Rosaline Y.C. Hsu, Yo-Chuen Lin, Christophe Redon, Qinyu Sun, Deepak K. Singh, Yating Wang, Vasudha Aggarwal, Jaba Mitra, Abhijith Matur, Branden Moriarity, Taekjip Ha, Mirit I. Aladjem, Kannanganattu V. Prasanth, Supriya G. Prasanth
Publikováno v:
iScience, Vol 23, Iss 5, Pp - (2020)
Summary: Telomeres are maintained by telomerase or in a subset of cancer cells by a homologous recombination (HR)-based mechanism, Alternative Lengthening of Telomeres (ALT). The mechanisms regulating telomere-homeostasis in ALT cells remain unclear.
Externí odkaz:
https://doaj.org/article/ffd7c76cb510474a8bfbcdf73ec5267e
Autor:
Yo-Chuen Lin, Dazhen Liu, Arindam Chakraborty, Virgilia Macias, Eileen Brister, Jay Sonalkar, Linyuan Shen, Jaba Mitra, Taekjip Ha, Andre Kajdacsy-Balla, Kannanganattu V. Prasanth, Supriya G. Prasanth
Publikováno v:
Molecular and Cellular Biology. 43:143-156
Autor:
Qinyu Hao, Xinying Zong, Qinyu Sun, Yo-Chuen Lin, You Jin Song, Seyedsasan Hashemikhabir, Rosaline YC Hsu, Mohammad Kamran, Ritu Chaudhary, Vidisha Tripathi, Deepak Kumar Singh, Arindam Chakraborty, Xiao Ling Li, Yoon Jung Kim, Arturo V Orjalo, Maria Polycarpou-Schwarz, Branden S Moriarity, Lisa M Jenkins, Hans E Johansson, Yuelin J Zhu, Sven Diederichs, Anindya Bagchi, Tae Hoon Kim, Sarath C Janga, Ashish Lal, Supriya G Prasanth, Kannanganattu V Prasanth
Publikováno v:
eLife, Vol 9 (2020)
Cell cycle is a cellular process that is subject to stringent control. In contrast to the wealth of knowledge of proteins controlling the cell cycle, very little is known about the molecular role of lncRNAs (long noncoding RNAs) in cell-cycle progres
Externí odkaz:
https://doaj.org/article/6d53b6080b7048e8ae1613e0cfdb4673
Autor:
Fredy, Kurniawan, Supriya G, Prasanth
Publikováno v:
Transcription. 13:82-87
Transcription regulation is an important mechanism that controls pluripotency and differentiation. Transcription factors dictate cell fate decisions by functioning cooperatively with chromatin regulators. We have recently demonstrated that BEND3 (BAN
Autor:
Mahdieh Jadaliha, Omid Gholamalamdari, Wei Tang, Yang Zhang, Ana Petracovici, Qinyu Hao, Aamira Tariq, Tae Gyoon Kim, Sarah E Holton, Deepak K Singh, Xiao Ling Li, Susan M Freier, Stefan Ambs, Rohit Bhargava, Ashish Lal, Supriya G Prasanth, Jian Ma, Kannanganattu V Prasanth
Publikováno v:
PLoS Genetics, Vol 14, Iss 11, p e1007802 (2018)
The human genome encodes thousands of long noncoding RNA (lncRNA) genes; the function of majority of them is poorly understood. Aberrant expression of a significant number of lncRNAs is observed in various diseases, including cancer. To gain insights
Externí odkaz:
https://doaj.org/article/a0328846c8c04517aa1e82a87eb95ca4
Publikováno v:
BioEssays. 45
Autor:
Qinyu Hao, Minxue Liu, Swapna Vidhur Daulatabad, Saba Gaffari, Rajneesh Srivastava, You Jin Song, Shivang Bhaskar, Anurupa Moitra, Hazel Mangan, Elizabeth Tseng, Rachel B. Gilmore, Susan M. Freier, Xin Chen, Chengliang Wang, Sui Huang, Stormy Chamberlain, Hong Jin, Jonas Korlach, Brian McStay, Saurabh Sinha, Sarath Chandra Janga, Supriya G. Prasanth, Kannanganattu V. Prasanth
Out of the several hundred copies of rRNA genes that are arranged in the nucleolar organizing regions (NOR) of the five human acrocentric chromosomes, ∼50% remain transcriptionally inactive. NOR-associated sequences and epigenetic modifications con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::853f0f42a95598355aebac8008687fdc
https://doi.org/10.1101/2022.07.04.498693
https://doi.org/10.1101/2022.07.04.498693
Autor:
Yo-Chuen Lin, Dazhen Liu, Arindam Chakraborty, Lyudmila Y. Kadyrova, You Jin Song, Qinyu Hao, Jaba Mitra, Rosaline Y. C. Hsu, Mariam K. Arif, Sneha Adusumilli, Ting-Wei Liao, Taekjip Ha, Farid A. Kadyrov, Kannanganattu V. Prasanth, Supriya G. Prasanth
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(22)
In eukaryotes, the origin recognition complex (ORC) is required for the initiation of DNA replication. The smallest subunit of ORC, Orc6, is essential for prereplication complex (pre-RC) assembly and cell viability in yeast and for cytokinesis in met
Autor:
Fredy Kurniawan, Neha Chetlangia, Mohammad Kamran, Christophe E. Redon, Lorinc Pongor, Qinyu Sun, Yo-Chuen Lin, Vijay Mohan, Oways Shaqildi, Darya Asoudegi, Qinyu Hao, Abid Khan, Mirit I. Aladjem, Kannanganattu V. Prasanth, Supriya G. Prasanth
Publikováno v:
Proceedings of the National Academy of Sciences. 119
BEN domain-containing proteins are emerging rapidly as an important class of factors involved in modulating gene expression, yet the molecular basis of how they regulate chromatin function and transcription remains to be established. BEND3 is a quadr